100+ bought since yesterday, try a subscriptionOverall pick
Visit the Enfamil Store

Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub

Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz TubEnfamil Enspire Optimum Baby Formula Immune Supporting Lactoferrin found Colostrum Our Closest Formula Breast Milk Dual Prebiotics Infant Formula Pow3 pack Enfamil Optimum Powder Baby Formula Our Closest to Breast Milk 20 5 oz Tub2 pack Enfamil Optimum Powder Baby Formula Our Closest to Breast Milk 20 5 oz Tub4 pack Enfamil Optimum Powder Baby Formula Our Closest to Breast Milk 20 5 oz Tub
Multipack Quantity:1

Key item features

  • NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
  • SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
  • COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
  • TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
  • NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
  • PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
  • JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase. 
  • CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Current price is $46.96$2.29/oz
Price when purchased online
  • Free shipping
  • Free 90-day returns
Subscribe, Your usuals, on your schedule, Save time and stay stocked!, $46.96
Your usuals, on your schedule
Save time and stay stocked!
One-time purchase $46.96

How do you want your item?

Try 30 days for just $1! Choose a plan at checkout.
How do you want your item?
Columbus, 43215
Arrives by Tomorrow
Low stock
Sold and shipped by Walmart.com
Free 90-day returns
This item is gift eligible
SNAP EBT eligible
walmart plus

Try 30 days of Walmart+ for just $1!

T&C apply.

About this item

Product details

Specifications

Indications

Directions

Warranty

Ingredients

Warnings

Refine your search

Customer ratings & reviews

4.7 out of 5 stars
stars4,072 ratings3,417 reviews
How item rating is calculated
  1. 5 stars86% (3,497)
  2. 4 stars9% (352)
  3. 3 stars2% (85)
  4. 2 stars1% (45)
  5. 1 star2% (93)

Reviews summary

Pros

  • : Formula is easy on baby's stomach.

Cons

  • : Formula's high cost is a significant drawback.
Generated by AI

Customer photos

  • +149 images
Filtered and sorted results would be available on the new 'Customer ratings & reviews' page.
Sort by |

Showing 1-3 of 3,417 reviews

Feb 14, 2026
Shelby
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Had to start supplementing and we chose this formula. I love the nutrition value and how close this formula is to breast milk. The transition was gentle on my little one's tummy. We will be using this formula permanently for supplementation.

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

We are so happy you chose us to help you supplement feedings for your little one, Shelby! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert

Aug 7, 2025
kaylie
Walmart Associate
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

i little on pricey side but my son was a bf baby and i worked alot and my supply wouldn't keep up with how much he wanted frist try useing and toke to it right away

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

We at Enfamil are so glad you're a part of our family, Kaylie! Thanks for taking time to leave a review! — Abby, Enfamil Expert

May 21, 2025
Leticia
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

After breastfeeding for 11 months...

After breastfeeding for 11 months i need it to transition my baby to formula and was a struggle my baby was refusing every formula until i tried this one, i am so grateful for Enfamil Optimum thank you for creating a formula so similar to breastmilk my baby couldn't tell the difference.

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

Thank you for telling us about your experience, Leticia. We are grateful for such a wonderful review! — Marcy, Enfamil Expert