Overall pick

Enfamil Optimum (Enspire) Gentlease Powder Baby Formula, Our Closest to Breast Milk 19.5 oz Tub

Key item features

  • NEW LOOK, UPDATED FORMULA: Enfamil Optimum Gentlease, formerly Enspire Gentlease, has a fresh new look and an improved formula designed for your little one’s comfort 
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum Gentlease is the first and only leading brand with lactoferrin (also found in colostrum and breast milk) and has dual HMOs for optimal immune support
  • EASY-TO-DIGEST PROTEINS: Gentle formula, specially formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • PREMIUM IMMUNE BLEND: Now has a dual prebiotic blend (2'FL & LnNT), key ingredients naturally present in breastmilk to support baby's developing immune system
  • PEACE OF MIND: Optimum contains NO artificial growth hormones, NO artificial colors or flavors, and is NON-GMO, offering complete nutrition for babies through 12 months
  • TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Trusted Brand for Brain-Building & Immune Support
  • SNAP ELIGIBLE: Eligible for purchase with Supplemental Nutrition Assistance Program (SNAP) benefits, providing greater accessibility for caring caretakers
Current price is $49.96$2.56/oz
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Customer ratings & reviews

4.7 out of 5 stars
stars1,213 ratings955 reviews
How item rating is calculated
5.0
4.9
4.6
4.7
4.0
0.9

Reviews summary

Pros

  • : Suitable for infants with digestive issues.
  • : Formula is easy on baby's stomach.
  • : Formula's protein and ingredients closely match those found in breast milk.
  • : Formula is gentle on baby's stomach.
  • : Reduces gas and discomfort in babies.

Cons

  • : Formula's cost may be a barrier for some buyers.
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Showing 1-3 of 955 reviews

Apr 4, 2026
Wendy
5 out of 5 stars review

Verified Purchase

Enfamil formula

I ranked the taste a 5star because this is the ONLY formula my granddaughter would drink. She was strictly a breastfed baby and had to start supplementing on occasion. She seemed to enjoy the taste and not mind the bottle, easily switched back and forth from breast to bottle. She suffers from reflux and this is gentle on the stomach. It is a bit pricey but for a picky infant with a sensitive tummy it's been liquid gold. At times additional stirring or shaking (I prefer not to shake, it causes bubbles) is needed to prevent clumping of the powder while mixing.

Helpful?2LM6WL6P5I4H588698782
May 28, 2025
Tee93
5 out of 5 stars review

Verified Purchase

one of a kind

only milk my baby will drink besides breast milk. we tried 4 different kinds. it is expensive but he likes it. this definitely addressed he gassiness issues

Helpful?2LM6WL6P5I4H588698782
reply from Enfamil Customer Care

We are so happy you chose us to help you supplement feedings for your little one, Tee93! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert

May 7, 2026
Amber
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

wonderful product

does exactly what it says on the label and I would highly recommend this product to moms with baby's that have intolerance to the reg enfamil

Helpful?2LM6WL6P5I4H588698782