Enfamil Optimum (Enspire) Gentlease Powder Baby Formula, Our Closest to Breast Milk 19.5 oz Tub
Enfamil Optimum (Enspire) Gentlease Powder Baby Formula, Our Closest to Breast Milk 19.5 oz Tub
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Enfamil Optimum (Enspire) Gentlease Powder Baby Formula, Our Closest to Breast Milk 19.5 oz Tub

1,425 ratings
Enfamil Optimum (Enspire) Gentlease Powder Baby Formula, Our Closest to Breast Milk 19.5 oz TubEnfamil Optimum Enspire Gentlease Powder Baby Formula Our Closest to Breast Milk 19 5 oz Tub2 pack Enfamil Optimum Enspire Gentlease Powder Baby Formula Our Closest to Breast Milk 19 5 oz Tub3 pack Enfamil Optimum Enspire Gentlease Powder Baby Formula Our Closest to Breast Milk 19 5 oz Tub4 pack Enfamil Optimum Enspire Gentlease Powder Baby Formula Our Closest to Breast Milk 19 5 oz Tub
Pack SizeSingle

Key item features

  • NEW LOOK, UPDATED FORMULA: Enfamil Optimum Gentlease, formerly Enspire Gentlease, has a fresh new look and an improved formula designed for your little one’s comfort 
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum Gentlease is the first and only leading brand with lactoferrin (also found in colostrum and breast milk) and has dual HMOs for optimal immune support
  • EASY-TO-DIGEST PROTEINS: Gentle formula, specially formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • PREMIUM IMMUNE BLEND: Now has a dual prebiotic blend (2'FL & LnNT), key ingredients naturally present in breastmilk to support baby's developing immune system
  • PEACE OF MIND: Optimum contains NO artificial growth hormones, NO artificial colors or flavors, and is NON-GMO, offering complete nutrition for babies through 12 months
  • TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Trusted Brand for Brain-Building & Immune Support
  • SNAP ELIGIBLE: Eligible for purchase with Supplemental Nutrition Assistance Program (SNAP) benefits, providing greater accessibility for caring caretakers

Specs

Brand, EnfamilAge range, 0Product line, Enspire GentleaseRec. use, Immune SupportFood form, PowdersSize, 19.5 oz

About this item

Product details

Introducing Enfamil Optimum, formerly known as Enfamil Enspire Optimum—now with a fresh new look but the same trusted nutrition for your little one. Enfamil Optimum is designed to be our closest formula to breast milk, it has lactoferrin, a key protein also found in colostrum and breast milk, and a premium immune blend. Perfect for combo feeding, Enfamil Optimum is ideal for supplementing breastfeeding, ensuring your baby gets essential nutrients while providing parents with convenience and peace of mind. Optimum has 2'FL & LnNT, two of the most abundant HMOs that are naturally present in breastmilk, to nourish their immune health. With NO artificial growth hormones, NO artificial colors or flavors, and a NON-GMO† formula, Enfamil Optimum has complete nutrition for babies through 12 months. Give your baby the best start with Enfamil—trusted by parents*, backed by science. †Not made with genetically modified ingredients, but trace amounts of genetically engineered materials may be present in the product from manufacturing environments and process sources. *Among those who have a preference; Based on the 2023 survey by AMC Global.
  • NEW LOOK, UPDATED FORMULA: Enfamil Optimum Gentlease, formerly Enspire Gentlease, has a fresh new look and an improved formula designed for your little one’s comfort 
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum Gentlease is the first and only leading brand with lactoferrin (also found in colostrum and breast milk) and has dual HMOs for optimal immune support
  • EASY-TO-DIGEST PROTEINS: Gentle formula, specially formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • PREMIUM IMMUNE BLEND: Now has a dual prebiotic blend (2'FL & LnNT), key ingredients naturally present in breastmilk to support baby's developing immune system
  • PEACE OF MIND: Optimum contains NO artificial growth hormones, NO artificial colors or flavors, and is NON-GMO, offering complete nutrition for babies through 12 months
  • TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Trusted Brand for Brain-Building & Immune Support
  • SNAP ELIGIBLE: Eligible for purchase with Supplemental Nutrition Assistance Program (SNAP) benefits, providing greater accessibility for caring caretakers
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.  

Specifications

Brand

Enfamil

Age range

0

Product line

Enspire Gentlease

Rec. use

Immune Support

Directions

Instructions

Your baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor. Ask your baby's doctor which formula is appropriate for your baby. Ask your baby's doctor whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.1) Wash hands thoroughly with soap and water before preparing formula.2) Pour desired amount of water into bottle. Add powder.3) Cap bottle and SHAKE WELL.Use chart on product label for correct amounts of water and powder. Use scoop in tub or can to measure powder. Store DRY scoop in lid holder in tub or in can.

Safe Handling Instructions

Do not use a microwave oven to warm formula. Serious burns may result. Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

Ingredients

Warnings

Customer ratings & reviews

4.7 out of 5 stars
stars
1,425 ratings1,072 reviews
How item rating is calculated
  1. 5 stars84% (1,202)
  2. 4 stars10% (142)
  3. 3 stars2% (30)
  4. 2 stars1% (14)
  5. 1 star3% (37)

Reviews summary

Pros

  • : Suitable for infants with sensitive stomachs.
  • : Formula is gentle on baby's stomach.
  • : Reduces gas and discomfort in infants.
  • : Reduces gas and discomfort in babies.
  • : The formula lessens abdominal pain and fussiness from bloating.

Cons

  • : Formula's high cost may deter some buyers due to limited budget.
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Showing 1-3 of 1,072 reviews

Sep 21, 2026
Reviewer name: abbster
5 out of 5 stars
5 out of 5 stars review

Wonderful for gentle tummies

[This review was collected as part of a promotion.] worked really good on my baby when switching her formula it was just too gentle for her after while, she needed something a little more so we went to the neuro pro gold can and shes handling it all well

Review from Enfamil
Helpful?2LM6WL6P5I4H588698782
reply from Consumer Care Nutrition

Hello abbster! We are glad to hear that you have been enjoying using our Enfamil Optimum Gentlease! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #9139492. Thanks! - Maria, Enfamil Expert

Aug 25, 2026
Reviewer name: Enfamil Optimim
5 out of 5 stars
5 out of 5 stars review

Excellent for growth and development

[This review was collected as part of a promotion.] Given that I'm not producing much breast milk it is important for me that my son receive a quality formula to help with his growing and development, and Enfamil Optimum Gentlease does just that. Our son is less fussy/gassy and overall enjoys drinking this formula.

Review from Enfamil
Helpful?2LM6WL6P5I4H588698782
reply from Enfamil Customer Care

Hello! We are glad to hear that you have been enjoying using our Enfamil® Optimum™ Gentlease®! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #8957454. Thanks! - Ashley, Enfamil Expert

Sep 2, 2026
Reviewer name: WeeWee73
5 out of 5 stars
5 out of 5 stars review

Gentle on my baby's stomach

I bought this formula for my first baby and he did so well on it. My second baby is due this week and I will use this formula to feed her. The formula is gentle and I know I can rely on the brand.

Review from Enfamil
Helpful?2LM6WL6P5I4H588698782
reply from Customer Care

We truly appreciate you choosing Enspire Gentlease for each of your babies. It means so much to us! We’re so glad you’re part of our Enfamil family! — Tasha, Enfamil Expert

Current price is $49.96$2.56/oz
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