Neutrogena On-The-Spot Acne Treatment. Benzoyl Peroxide Cream 2.5%, Pimple Cream, 0.75 oz
Neutrogena On-The-Spot Acne Treatment. Benzoyl Peroxide Cream 2.5%, Pimple Cream, 0.75 oz
Hero image 0 of Neutrogena On-The-Spot Acne Treatment. Benzoyl Peroxide Cream 2.5%, Pimple Cream, 0.75 oz, 0 of 8
100+ bought since yesterday, try a subscriptionOverall pick
Visit the Neutrogena Store

Neutrogena On-The-Spot Acne Treatment. Benzoyl Peroxide Cream 2.5%, Pimple Cream, 0.75 oz

2,022 ratings

Key item features

  • Neutrogena On-The-Spot Acne Spot Treatment with 2.5% benzoyl peroxide acne medicine
  • Clinically proven acne treatment for face helps skin start getting clearer from day 1
  • Vanishing acne cream formula absorbs quickly, works invisibly, and dries clear on skin
  • Benzoyl peroxide spot treatment penetrates pores to kill acne bacteria that cause pimples
  • Helps clear acne breakouts and helps prevent new pimples from forming
  • Helps relieve redness of acne pimples without over-drying, stinging, or burning
  • Fast-working pimple cream provides long-lasting acne protection all day
  • Lightweight benzoyl peroxide cream for targeted acne treatment and blemish control

Specs

Active ingredient name, Benzoyl PeroxideAcne cream type, Acne Spot TreatmentSkin care concern, AcneForm, GelBrand, NeutrogenaPrimary ingredient, Benzoyl Peroxide

About this item

Product details

Neutrogena On-The-Spot Acne Spot Treatment Cream with benzoyl peroxide 2.5%, is a clinically proven acne treatment for face that helps clear breakouts fast without over-drying, stinging, or burning. This gentle vanishing cream formula absorbs quickly, works invisibly, and is designed for acne-prone skin. The lightweight acne cream penetrates deep into pores to kill acne bacteria that cause pimples and helps prevent new ones from forming. Clinically proven to help skin start getting clearer from day 1, this pimple spot treatment helps relieve the redness of acne pimples while remaining gentle on skin. The fast-working formula provides long-lasting acne treatment protection and can be applied up to three times daily to affected areas. The 0.75 oz tube is ideal for targeted application and on-the-go use. Neutrogena Acne Spot Treatment Cream is an essential addition to your acne care routine for targeted acne control while supporting your skin care goals.
  • Neutrogena On-The-Spot Acne Spot Treatment with 2.5% benzoyl peroxide acne medicine
  • Clinically proven acne treatment for face helps skin start getting clearer from day 1
  • Vanishing acne cream formula absorbs quickly, works invisibly, and dries clear on skin
  • Benzoyl peroxide spot treatment penetrates pores to kill acne bacteria that cause pimples
  • Helps clear acne breakouts and helps prevent new pimples from forming
  • Helps relieve redness of acne pimples without over-drying, stinging, or burning
  • Fast-working pimple cream provides long-lasting acne protection all day
  • Lightweight benzoyl peroxide cream for targeted acne treatment and blemish control
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.  

Specifications

Active ingredient name

Benzoyl Peroxide

Acne cream type

Acne Spot Treatment

Skin care concern

Acne

Form

Gel

Indications

Directions

Instructions

• Clean the skin thoroughly before applying this product. • Cover the entire affected area with a thin layer one to three times daily. • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or directed by a doctor. • If bothersome dryness or peeling occurs, reduce application to once a day or every other day. • If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor. Other Information Store at 20°C-25°C (68°F-77°F). Questions? Call toll-free 800-582-4048 or 215-273-8755 (collect). www.neutrogena.com

Warranty

Warranty information

Please be aware that the warranty terms on items offered for sale by third party Marketplace sellers may differ from those displayed in this section (if any). To confirm warranty terms on an item offered for sale by a third party Marketplace seller, please use the 'Contact seller' feature on the third party Marketplace seller's information page and request the item's warranty terms prior to purchase.

Ingredients

Warnings

Refine your search

Customer ratings & reviews

4.3 out of 5 stars
stars
2,022 ratings1,320 reviews
Includes global ratings and reviews
How item rating is calculated
  1. 5 stars67% (1,355)
  2. 4 stars17% (342)
  3. 3 stars6% (122)
  4. 2 stars3% (55)
  5. 1 star7% (148)

Reviews summary

Pros

  • : Quickly reduces and eliminates pimples.
  • : Reduces acne and inflammation by morning.
  • : Minimizes inflammation associated with breakouts.
  • : The formula emits little to no fragrance and dissipates quickly.
  • : Enables convenient daily application.

Neutral

  • : Can be drying, but also gentle on some skin types.
Generated by AI
Filtered and sorted results would be available on the new 'Customer ratings & reviews' page.
Sort by |

Showing 1-3 of 1,320 reviews

Nov 20, 2025
Reviewer name: evgeniiav5_287
5 out of 5 stars
5 out of 5 stars review

Fast, gentle, and surprisingly effective for calmi

I've been really impressed with the Neutrogena On-the-Spot Acne Treatment. It works fast, absorbs quickly, and feels very lightweight on the skin. I love that it's effective without being too harsh — it didn't dry out my skin or cause irritation like many other acne treatments do. Every time I get a breakout, this product calms it down noticeably overnight and reduces redness within a day. It's definitely become a must-have in my skincare routine. Simple, gentle, and super effective — highly recommend!

Review from influenster.com
Helpful?478VBG3LCZY810849651
Jan 26, 2026
Reviewer name: christinal590_1455
5 out of 5 stars
5 out of 5 stars review

Helps spot treat!

I've been using this for over a year, this is my third bottle. I have acne prone skin and I spot treat with this. This will dry out acne overnight! I also apply it on top of acne throughout the day to keep it drying and honestly, works way better than pimple patches for me. Doesn't cause any irritation.

Review from influenster.com
Helpful?478VBG3LCZY810849651
Sep 19, 2025
Reviewer name: spitza_2034
5 out of 5 stars
5 out of 5 stars review

Effective, affordable, and fast-acting acne treatm

Effective and fast-acting acne treatment. Gentle 2.5% benzoyl peroxide lotion. I do not experience any peeling with this treatment. The lotion blends into the skin easily. There is no white paste left on the skin. It has a minimal scent that quickly dissipates. The tube is pliable and product comes out easily. For acne and pimples that do not require a trip to the dermatologist, this is a great treatment that works and doesn't cost a lot of money.

Review from influenster.com
Helpful?478VBG3LCZY810849651
Current price is $8.97$11.96/oz
Price when purchased online
  • Free 90-day returns
Subscribe, Your usuals, on your schedule, Save time and stay stocked!, $8.97
Your usuals, on your schedule
Save time and stay stocked!
One-time purchase $8.97

How do you want your item?

Try 30 days for just $1! Choose a plan at checkout.
How do you want your item?
Ships to
Arrives by Tomorrow
Sold and shipped by Walmart.com
Free 90-day returns
This item is gift eligible
Benefits eligible (FSA/HSA) 

More seller options (3)

Starting from $15.41
walmart plus

Try 30 days of Walmart+ for just $1!

T&C apply.