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Differin Acne Treatment Gel with 0.1% Adapalene, Prescription-Strength Retinoid Clears & Prevents Acne, Fragrance-Free, 1.6 oz (45g) Pump ​

4.5 stars out of 375 reviews
(4.5)|
375 ratings
Count:1
Size:2.8"L x 1.69"W x 7"H

Key item features

  • Acne Targeting: Features 0.1% adapalene, an Rx-strength retinoid that targets acne deep within pores in 5 minutes and prevents new breakouts.
  • Cellular Normalization: Normalizes skin cell turnover to address clogged pores and inflammation, two primary causes of acne, without requiring a prescription.
  • Rapid Results: Users may begin to see results in as little as one week, with continuous use potentially reducing acne by up to 87% in 12 weeks.
  • Tone Restoration: Helps restore the skin's natural tone and texture by effectively reducing acne.
  • Daily Application: Apply once daily after cleansing; do not rinse off. Use with SPF 30+ sunscreen during the day and a non-SPF moisturizer at night.
  • Broad Efficacy: Effectively treats and prevents various forms of acne, including blackheads, whiteheads, blemishes, and clogged pores, even those caused by face masks.
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was $29.99
$14.98/oz
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Columbus, 43215
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4.5 out of 5 stars
stars375 ratings70 reviews
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Showing 1-3 of 70 reviews

Feb 18, 2026
WalmartCustomer
Item details
Count: 1
Size: 2.8"L x 1.69"W x 7"H
5 out of 5 stars review

Verified Purchase

0.1% Adapalene is the same everywhere, and in my experience, Differin is of transparent quality and competitive. Walmart priced it very reasonably compared to MRSP, and housed it in a shipping box that allowed the product to not be destroyed before opening.

Incentivized Review
Helpful?458FLPNM4ZA9725073812
Feb 12, 2026
B
Item details
Count: 1
Size: 2.8"L x 1.69"W x 7"H
5 out of 5 stars review

Verified Purchase

It Works!

I am an older adult with cystic acne related to psoriasis. This product is very effective in preventing breakouts and also works as a wrinkle-preventative. Very little is required to cover one's entire face. It comes in several dispensers, be sure to choose the one you prefer, tube or pressurized container.

Helpful?458FLPNM4ZA9725073812
Oct 15, 2025
Mike
Top Reviewer
Item details
Count: 1
Size: 2.8"L x 1.69"W x 7"H
5 out of 5 stars review

Verified Purchase

Affordable Retinoid

This is an outstanding product at an affordable price. Differin (adapalene) is the only otc retinoid that I can recall, plus offered by Walmart at an affordable price.

Helpful?458FLPNM4ZA9725073812