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Equate

Equate Extra Strength Anti-Itch and Skin Protectant Cream Diphenhydramine HCl 2%, 1 oz, Compare to Extra Strength Benadryl® Cream Active Ingredient

Equate Extra Strength Anti-Itch and Skin Protectant Cream Diphenhydramine HCl 2%, 1 oz, Compare to Extra Strength Benadryl® Cream Active IngredientEquate Extra Strength Anti Itch and Skin Protectant Cream 1 oz3 pack Equate Extra Strength Anti Itch and Skin Protectant Cream 1 oz
Multipack Quantity:1

Key item features

  • Active Ingredients: This product contains diphenhydramine hydrochloride 2 percent (topical analgesic) and zinc acetate 0.1 percent (skin protectant), which compares to the active ingredients of Extra Strength Benadryl Itch Stopping Cream
  • Fast Relief: Provides fast relief for most outdoor itches due to bug bites, sunburn and rashes from poison ivy, poison oak or poison sumac
  • Extra Strength Itch Relief: Equate Extra Strength Anti-Itch and Skin Protectant Cream also treats minor skin irritations, such as minor burns, scrapes and cuts
  • Rash Relief: Use Equate Extra Strength Anti-Itch and Skin Protectant Cream on poison ivy, poison oak and poison sumac for fast relief
  • FIRST AID: First aid anti-itch and skin protectant will help to keep you from itching irritated skin
Current price is $2.84$2.84/oz
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Customer ratings & reviews

4.6 out of 5 stars
stars2,450 ratings454 reviews
How item rating is calculated
  1. 5 stars76% (1,870)
  2. 4 stars13% (330)
  3. 3 stars5% (120)
  4. 2 stars2% (41)
  5. 1 star4% (89)

Reviews summary

Pros

  • : Provides great amount at a low cost.
  • : Relieves itch and inflammation from rashes.
  • : Made with amazing materials and craftsmanship.
  • : Simple application process with minimal effort.
  • : Relieves itch and calms skin irritation.

Neutral

  • : Can be pleasant and long-lasting, but also unpleasant and overpowering.
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Showing 1-3 of 454 reviews

Apr 9, 2026
Dennis
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

This one worked for me!

When i was bed-ridden, I experienced intense itching and this brand was the only one of about 4 anti-itch drugs I tried that actually worked for me! It worked quickly within minutes %26 really stopped the itching. And no super harsh/questionable ingredients like some of the other anti-itch drugs. I went through a great number of these tubes and it always worked.

Helpful?3HZLJPA4B35L228680027
Apr 17, 2025
jill
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Calms My Itchy Skin, Fantastic ‘Equate Brand!!

nicely because any soap I use??? There's always a chance I'm going to itch! This does it what it says it does with a great price and no smell! skin rubbing against other skin! I'm very fair complected and this works nàcdxdddzfdzfdzfdfdzfddddddzxzddddzxdxzdxzdzxdddzfdzfddzfdzfdzfdfqicely because any soap I use there's always a chance I'm going to itch! It does it what it says it does with a great price and no smell! this cream does what it's supposed to do! It comes my skin from everything from soap irritation to just smaller bug bites! It's a fantastic price at the equate brand is marvelous! to just smaller bug bites! It's a fantastic price at the equate brand is marvelous!

Helpful?3HZLJPA4B35L228680027
Aug 24, 2025
Kathy
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Product works quickly; roll-on makes it easy for me to apply to myself (and easy for others to help when necessary); treatment lasts several hours; I have used this product for a long time and never built-up a resistance to it.

Helpful?3HZLJPA4B35L228680027