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Differin Acne Treatment Gel with 0.1% Adapalene, Prescription-Strength Retinoid Clears & Prevents Acne, Fragrance-Free, 1.6 oz (45g) Pump ​

Key item features

  • Acne Targeting: Clears existing breakouts deep in pores and prevents new acne from forming, restoring skin's texture and tone.
  • Unique Mechanism: Normalizes skin cell turnover, effectively targeting clogged pores and inflammation, which are primary causes of acne.
  • Potent Retinoid: Contains 0.1% adapalene, a prescription-strength retinoid created for superior tolerability compared to other retinoid products.
  • Dermatologist Recommended: Features a water-based, oil-free, alcohol-free, fragrance-free, and non-comedogenic formula that helps reduce scarring and hyperpigmentation.
  • Proven Efficacy: Clinical studies show up to an 87% reduction in acne breakouts after 12 weeks, with continued improvement with further use.
  • Versatile Treatment: Effectively treats and prevents breakouts, blackheads, whiteheads, blemishes, and clogged pores, including acne caused by face masks.
  • Rapid Results: Users may start to see results in as little as 1 week when used as directed, with significant reduction in acne within 12 weeks.
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Current price is $23.97$14.98/oz
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4.6 out of 5 stars
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461 ratings66 reviews
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Showing 1-3 of 66 reviews

Jun 10, 2026
koren
Item details
Count: 1
Size: 2.8"L x 1.69"W x 7"H
5 out of 5 stars review

Verified Purchase

The small one cost me $20 on Amazon, that's three times more material, $30, very satisfied

Helpful?458FLPNM4ZA9725073812
Oct 10, 2024
Lisa
5 out of 5 stars review

Verified Purchase

The BEST Retinoid I've ever used

Many retinols or retinoids I've tried leave my skin feeling oily which I despise. I LOVE not only the texture of this formula, but also the ingredients! I'm up to using this daily and my skin has never looked and felt better!! Try the smaller version first to see if your skin agrees with it(follow directions %26 DO NOT use daily when first starting). If your skin does well, get the larger version. I'm in love with it! I cannot go more than a day without using mine. Also love other products from the Differing Line!

Helpful?458FLPNM4ZA9725073812
Feb 18, 2026
WalmartCustomer
Item details
Count: 1
Size: 2.8"L x 1.69"W x 7"H
5 out of 5 stars review

Verified Purchase

0.1% Adapalene is the same everywhere, and in my experience, Differin is of transparent quality and competitive. Walmart priced it very reasonably compared to MRSP, and housed it in a shipping box that allowed the product to not be destroyed before opening.

Incentivized Review
Helpful?458FLPNM4ZA9725073812