Enfamil Enspire Gentlease Infant Formula with Immune-Supporting Lactoferrin, Brain Building DHA, Helps Reduce Spit-up, Powder Refill Box, 29 oz
Enfamil Enspire Gentlease Infant Formula with Immune-Supporting Lactoferrin, Brain Building DHA, Helps Reduce Spit-up, Powder Refill Box, 29 oz
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Enfamil Enspire Gentlease Infant Formula with Immune-Supporting Lactoferrin, Brain Building DHA, Helps Reduce Spit-up, Powder Refill Box, 29 oz

4.7 stars out of 2640 reviews
(4.7)|
2,640 ratings

Key item features

  • EASY-TO-DIGEST GENTLE PROTEINS: Designed to be easy for developing digestive systems to digest
  • ALL IN ONE COMFORT: Enfamil Enspire Gentlease is scientifically formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • HELPS TO EASE COLIC: Clinically shown to ease fussiness, gas and crying in 24 hours
  • BRAIN BUILDING & IMMUNE SUPPORT: DHA has been shown to support brain development and Lactoferrin is a protein found in Colostrum that supports the immune system
  • PEDIATRICIAN RECOMMENDED: Enfamil is the #1 Infant Formula brand recommended by pediatricians**
  • NON-GMO: Enspire is a non-GMO baby formula that is designed to provide complete nutrition for babies through 12 months
  • SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits
  • https://www.walmart.com/m/brands/enfamil
Current price is $54.99$1.90/fl oz
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Customer ratings & reviews

4.7 out of 5 stars
stars2,640 ratings2,632 reviews
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Reviews summary

Pros
  • : Helps babies sleep for extended durations.
  • : Eases stomach issues and aids digestion.
  • : Reduces spit-up and discomfort during feedings.
  • : Reduces gas and fussiness in babies.
Cons
  • : Formula's cost is a significant drawback for many users.
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Showing 1-3 of 2,632 reviews

Jan 27, 2026
KyTor
5 out of 5 stars review

Best on the market when combo feeding!

I bought this about a month ago to give our baby a leg up. We are breastfeeding but his metabolism was burning through calories despite having breastmilk to spare! We started this formula and combo feeding and it's like he doesn't even notice the difference. The gentle ease version is great as well for overall gas.

Review from Enfamil
Helpful?1WIMZTX2QLHB327388827
reply from Customer Care

Thank you for sharing your experience using our product, KyTor! We appreciate your feedback! — Tasha, Enfamil Expert

Jan 19, 2026
Faiu
5 out of 5 stars review

Great formula

[This review was collected as part of a promotion.] The formula is easy to digest and does not cause too much gas or constipation. Since using Enfamil, my baby is growing well, gaining weight normally, and seems calmer. I like that it contains DHA and vitamins that support brain and body development. I am very satisfied and I highly recommend Enfamil for 4-month-old babies.

Review from Enfamil
Helpful?1WIMZTX2QLHB327388827
reply from Enfamil Customer Care

Hello! We would love to speak with you directly about your experience with our Enspire Optimum! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7847646. We look forward to speaking with you and seeing how we can help! -Bev, Enfamil Expert 

Nov 25, 2025
Kaylene
5 out of 5 stars review

Baby Loves

[This review was collected as part of a promotion.] I cannot say enough good things about this baby formula. As a new mom, finding something that's gentle on my baby's stomach and helps him feel full and happy has been such a relief. Since switching to this formula, my little one has had zero tummy troubles—no gas, no fussiness, just a content baby who sleeps better and eats consistently.

Review from Enfamil
Helpful?1WIMZTX2QLHB327388827
reply from Customer Care

Thank you for telling us about your experience, Kaylene. We are grateful for such a wonderful review! — Abby, Enfamil Expert