Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, (Hardcover)

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Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, (Hardcover)
Author: Springer
ISBN: 9780387767604
Format: Hardcover
Publication Date: 2008-06-23
Page Count: 443

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Book format
Hardcover
Fiction/nonfiction
Non-Fiction
Genre
Textbooks
Pub date
20080623
Pages
443
Subgenre
Neuroscience

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Reelin glycoprotein is a serine protease with important roles in embryogenesis and during adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and reelin signaling impairment in brain. Reelin abnormalities in several neurospychiatric disorders, such as autism, schizophrenia, mood disorders and lissencephaly, may provide mechanistic explanations for etiologies of these disorders. There is also emerging data indicating the feasibility of using various medications (valproic acid, olanzapine) to increase mRNA/protein levels for reelin and/or gene therapy to prevent or treat reelin deficiencies observed in the above-mentioned disorders.

This comprehensive and integrative book examines the role that reelin plays in the etiology of various neuropsychiatric disorders, including schizophrenia and autism.

Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, (Hardcover)
Author: Springer
ISBN: 9780387767604
Format: Hardcover
Publication Date: 2008-06-23
Page Count: 443

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Specifications

Book format

Hardcover

Fiction/nonfiction

Non-Fiction

Genre

Textbooks

Pub date

20080623

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