
Patients VIH/TB-MR sous régime court de tuberculose multiresistante (Paperback)
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Patients VIH/TB-MR sous régime court de tuberculose multiresistante (Paperback)
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- Book formatPaperback
- Fiction/nonfictionNon-Fiction
- GenreMedical/General
- Pages52
- EditionStandard Edition
- PublisherKS Omniscriptum Publishing
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Une étude rétrospective à visée descriptive a été mené chez des patients atteints de TBMR dans les CAT, les services de pneumo-phytisiologie de Cocody et Treichville, de novembre 2013 à décembre 2015. Les expectorations des patients inclus ont été mises en culture mensuellement pendant 9 mois. Sur 132 patients mis sous régime court de 9 mois, 22 (16,66%) étaient infectés par le VIH dont 6 cas de rechute et 4 perdus de vue. A la phase de consolidation du traitement court de TBMR, les cultures ont été négatives pour 14/18 (77,77%) et positives pour 4/18 (22,22%). La mutation D516V dans le gène rpoB était la plus fréquente parmi les guéris avec 42,85%. Un échec a été observé chez un patient infecté par une souche doublement mutée (L511P, S522T). Parmi les échecs, 2 patients étaient XDR. L'Odd ratio estimé selon le type de mutation dans gène rpoB et la catégorie clinique était respectivement 0,81 IC 95% [0,13;20,57] et 0,27 IC 95% [0,002; 2,82]. Le type de mutation dans gène rpoB et la catégorie clinique n'influeraient pas le devenir thérapeutique des patients co-infectés VIH/TBMR.
Patients VIH/TB-MR sous régime court de tuberculose multiresistante (Paperback)
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Specifications
Book format
Paperback
Fiction/nonfiction
Non-Fiction
Genre
Medical/General
Pages
52
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