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Differin Prescription-Strength Retinoid Acne Treatment Gel for Face with 0.1% Adapalene, Clears & Prevents Acne, Fragrance-Free, 15g Tube​

4.4 stars out of 7221 reviews
(4.4)|
7,221 ratings

Key item features

  • TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
  • CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
  • RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
  • DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
  • REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
  • THE CREATORS OF ADAPALENE: A Retinoid that Fights Acne
  • TRAVEL SIZE TOILETRIES: This product is under 3.4 fl oz, making it easy to take with you on your next vacation or trip
Current price is $13.48$26.96/oz
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Customer ratings & reviews

4.4 out of 5 stars
stars7,221 ratings5,124 reviews
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Reviews summary

Pros
  • : Offers great value for the cost.
  • : Helps to dry out and clear up pimples rapidly.
  • : Helps clear acne, dark spots, and hyperpigmentation.
  • : Helps to clear and prevent breakouts.
  • : Convenient to apply with minimal effort.
Neutral
  • : Can be drying, but gentle and non-irritating for others.
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Showing 1-3 of 5,124 reviews

Nov 10, 2020
Jenny
5 out of 5 stars review

Verified Purchase

Works better the longer you use it

I've been using this since February 2020 and it has cleared up my acne. I still have some acne scars but they're slowly fading away. I was mostly clear by the 3 month mark and it got better from there. I did not experience a purging period with this but I hear some people do. I've used benzoyl peroxide and retina before and I think this worked better and it doesn't bleach my sheets. I do still get the occasional premenstrual breakout but as long as I use this consistently it goes away pretty quickly. Some days my skin can feel a little dry so I skip applying it at night and just add extra moisturizer and continue the next day. You only need to apply a pea-sized amount at night. I find this tiny tube lasts me about 2 to 3 months before I need to get a refill. Highly recommend! See my before, 3 month and current photo.

Helpful?711f7520-4507-11f0-8d8f-136482466119127541271
Feb 25, 2026
katalinaB
5 out of 5 stars review

Dries out blemishes and renews the skin!

loveeee differn gel! Whenever I have a new pimple or blemishes I moisturize and then apply just a small amount, usually putting the tip and dispensing from that, over the area and re apply moisturizer! It has really helped get rid of my acne and it's super helpful! It will dry you out and might make your makeup look weird but Just keep moisturizing! I'd also advise to not pick at the dryed skin or area because it will make your skin worse and red!! It has no scent and I'd be careful if you have sensitive skin because this can be heavy duty depending on how much you put on !! 🤍

Review from influenster.com
Helpful?711f7520-4507-11f0-8d8f-136482466119127541271
May 6, 2024
Lauren
5 out of 5 stars review

Verified Purchase

Smoother, and more even skin.

So I i ve been using this for about a month and half now, and the main thing I notice is that I i dont break out as much, a lot of my dark spots are fading, and I think overall my skin is looking more even and healthy. Now i've read online that it takes about 3 months for you to see a HUGE difference so hopefully by that time my skin looks even better. I'll definitely be buying again

Helpful?711f7520-4507-11f0-8d8f-136482466119127541271