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100+ bought since yesterdayOverall pick
Equate Max Strength Severe Cold & Flu Relief Daytime and Nighttime Combo Pack, 12 fl oz
Key item features
- Compare this daytime and nighttime cold medicine to Vicks® DayQuil® Severe and Vicks NyQuil® Severe active ingredients
- Temporarily relieves nasal and sinus congestion and sinus pressure
- Soothes cough from minor throat and bronchial irritation
- Daytime contains Acetaminophen, Dextromethorphan HBr, Guaifenesin, and Phenylephrine HCl for effective relief
- Nighttime contains Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, and Phenylephrine HCl to help you rest
- Alcohol-free, gluten-free; day formula thins mucus, night formula reduces sneezing and runny nose for better sleep
Specs
- Health concernCold
- SymptomsCough, Cold, Flu
- Ingredient preferenceAlcohol-Free
- Medicine strength650 mg / 325 mg
- Age groupTeen, Adult
- FormLiquid
Reviews summary
Pros
- : Offers similar quality at lower cost.
- : Provides quick comfort for scratchy throats.
- : Relieves severe headaches to a bearable level.
- : Relieves nasal congestion and sinus pressure.
Neutral
- : Can be fruity, but also bitter or unpleasant.
- : Can be effective for some, but has an unpleasant taste for others.
Generated by AI
Current price is USD$11.6748.6 ¢/fl oz
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About this item
Product details
Get multi-symptom relief with Equate Max Strength Severe Cold & Flu Relief combo. Compare to Vicks® DayQuil®and NyQuil®* Severe active ingredients. The Daytime formula relieves nasal and sinus congestion, cough, headache, fever, sore throat, and chest congestion while thinning mucus for easier coughing. The Nighttime formula soothes aches, sneezing, runny nose, and helps you get the rest you need. Both are alcohol-free and gluten-free, relieving sinus pressure, minor pain, and cough from throat and bronchial irritation. Daytime is antihistamine free; Nighttime is sugar-free and mixed berry flavored. This combo pack offers trusted relief to keep you comfortable day and night with same active ingredients as the leading brands,at a lower price. * Vicks® NyQuil® and DayQuil® are registered trademarks of The Procter & Gamble Company
- Compare this daytime and nighttime cold medicine to Vicks® DayQuil® Severe and Vicks NyQuil® Severe active ingredients
- Temporarily relieves nasal and sinus congestion and sinus pressure
- Soothes cough from minor throat and bronchial irritation
- Daytime contains Acetaminophen, Dextromethorphan HBr, Guaifenesin, and Phenylephrine HCl for effective relief
- Nighttime contains Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, and Phenylephrine HCl to help you rest
- Alcohol-free, gluten-free; day formula thins mucus, night formula reduces sneezing and runny nose for better sleep
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Health concern
Cold
Symptoms
Cough, Cold, Flu
Ingredient preference
Alcohol-Free
Medicine strength
650 mg / 325 mg
Indications
Stop Use Indications
Nighttime Severe Cold & Flu: Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; heart disease; high blood pressure; thyroid disease; diabetes; glaucoma; cough that occurs with too much phlegm (mucus); a breathing problem such as emphysema or chronic bronchitis; trouble urinating due to an enlarged prostate gland; persistent or chronic cough such as occurs with smoking, asthma, or emphysema; a sodium-restricted diet. Ask a doctor or pharmacist before use if you are: taking sedatives or tranquilizers; taking the blood thinning drug warfarin. When using this product: do not use more than directed; excitability may occur, especially in children; marked drowsiness may occur; avoid alcoholic drinks; be careful when driving a motor vehicle or operating machinery; alcohol, sedatives, and tranquilizers may increase drowsiness. Stop use and ask a doctor if: you get nervous, dizzy or sleepless; pain, nasal congestion, or cough gets worse or lasts more than 7 days; fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. Daytime Severe Cold & Flu: Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if: adult takes more than 4,000 mg of acetaminophen in 24 hours; child takes more than 5 doses in 24 hours; taken with other drugs containing acetaminophen; adult has 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; heart disease; thyroid disease; diabetes; high blood pressure; trouble urinating due to an enlarged prostate gland; cough that occurs with too much phlegm (mucus); persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema. Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin. When using this product do not use more than directed. Stop use and ask a doctor if: you get nervous, dizzy or sleepless; pain, nasal congestion or cough gets worse or lasts more than 5 days (children) or 7 days (adults); fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Cold
Directions
Dosage
Nighttime: Active Pharmaceutical Ingredient: Acetaminophen 650 mg Dextromethorphan HBr 20 mg Doxylamine succinate 12.5 mg Phenylephrine HCl 10 mg Daytime: Active Pharmaceutical Ingredient: Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg
Instructions
Nighttime Severe Cold & Flu: Directions: Take only as directed – see Overdose warning; only use the dose cup provided; do not exceed 4 doses per 24 hrs. Adults & children 12 yrs & over: 30 mL every 4 hours; children 4 to under 12 yrs: ask a doctor; children under 4 yrs: do not use. Daytime Severe Cold & Flu: Directions: Take only as directed – see Overdose warning; only use the dose cup provided; do not exceed 4 doses per 24 hrs. Adults & children 12 yrs & over: 30 mL every 4 hours; children 6 to under 12 yrs: 15 mL every 4 hrs; children 4 to under 6 yrs: ask a doctor; children under 4 yrs: do not use.
Ingredients
Inactive Ingredients
Daytime: butylated hydroxyanisole, edetate disodium, FD&C yellow #6, flavor, glycerin, menthol, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum Nighttime: butylated hydroxyanisole, edetate disodium, FD&C blue #1, FD&C red #40, flavor, glycerin, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum
Ingredients
Nighttime Severe Cold & Flu: Active ingredients (in each 30 mL): Acetaminophen 650 mg; Dextromethorphan HBr 20 mg; Doxylamine succinate 12.5 mg; Phenylephrine HCl 10 mg. Inactive ingredients: anhydrous citric acid, edetate disodium, FD&C blue #1, FD&C red #40, flavor, glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol solution, sucralose, xanthan gum. Daytime Severe Cold & Flu: Active ingredients (in each 15 mL): Acetaminophen 325 mg; Dextromethorphan HBr 10 mg; Guaifenesin 200 mg; Phenylephrine HCl 5 mg. Inactive ingredients: butylated hydroxyanisole, edetate disodium, FD&C yellow #6, flavor, glycerin, menthol, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum.
Active Ingredients
Phenylephrine HCl 5 mg Guaifenesin HBr 10 mg Dextromethorphan HBr 10 mg Acetaminophen 325 mg
Active Ingredient Name
Acetaminophen Dextromethorphan HBr Doxylamine succinate Phenylephrine HCl
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Customer ratings & reviews
How item rating is calculated
4.8
5.0
5.0
5.0
2.1
3.3
Reviews summary
Pros
- : Offers similar quality at lower cost.
- : Provides quick comfort for scratchy throats.
- : Relieves severe headaches to a bearable level.
- : Relieves nasal congestion and sinus pressure.
Neutral
- : Can be fruity, but also bitter or unpleasant.
- : Can be effective for some, but has an unpleasant taste for others.
Generated by AI
Customer photos
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Showing 1-3 of 220 reviews
Apr 7, 2026
Scott
Top Reviewer
5 out of 5 stars review
Verified Purchase
Life saver for cold and flu
A much needed help for bad colds and flu. Starts working immediately
Helpful?15QWD15FNR7639661521
Oct 25, 2025
Alexis
5 out of 5 stars review
Verified Purchase
The relief was great.
I'm not a fan of most syrups of this type, but the cherry flavor was palatable for the time I used it. The soothing effect on my throat was immediate, and my coughing subsided in about 10 minutes. I would compare it well to its name brand counterpart. It helped me greatly through my serious fever.
Helpful?15QWD15FNR7639661521
Apr 9, 2026
Leeannder
Top Reviewer
5 out of 5 stars review
Verified Purchase
This Stuff works! Got rest/got well!
Was sick as a dog. (Wonder why they say that? Never had a very sick dog.) Anyway... until just an hour after I took my FIRST dose of the daytime relief, I thought I was going to go one of those Emergency Care Clinics, which I detest. AMAZING! Coughing til I lost my breath %26 my ribs hurt magically stopped. Constant nose blowing ended. Even the headache that hurt so much my eyes almost crossed ---- eased to bearable. When I took the Night Time stuff, I slept so hard, when I woke, my hair wasn't even messed up. That's some good rest! I was OVER IT completely, with more than a quarter of each bottle left! How's that for good medicine?
Helpful?15QWD15FNR7639661521
