Differin Acne Treatment Gel, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 1.6 OZ
Key item features
- Acne Targeting: Clears existing breakouts deep within pores and prevents new acne from forming, ultimately restoring the skin's texture and tone.
- Advanced Treatment: Works by normalizing skin cell turnover, effectively targeting clogged pores and inflammation, which are primary causes of acne.
- Potent Retinoid: Contains 0.1% Adapalene, an RX-strength retinoid created for superior tolerability compared to other prescription retinoid products.
- Gentle Formulation: A dermatologist-recommended, water-based formula that is oil-free, alcohol-free, fragrance-free, and non-comedogenic, helping to reduce scarring and hyperpigmentation.
- Proven Efficacy: Clinical studies show up to an 87% reduction in acne breakouts after 12 weeks, with results potentially visible in as little as one week.
- Travel-Friendly Size: Packaged in a 1.6 oz container, making it suitable for travel and easy to carry on trips.
Specs
- Ingredient preferenceOil-Free
- Ingredient propertiesNon-Comedogenic
- ScentUnscented
- Net content statement45 g Tube
Reviews summary
Pros
- : Offers great value for the cost.
- : Helps to dry out and clear up pimples rapidly.
- : Helps to clear and prevent breakouts.
- : Convenient to apply with minimal effort.
Neutral
- : Can be drying, but gentle and non-irritating for others.
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About this item
Product details
Differin Adapalene Gel 0.1% Acne Treatment with Retinoid, It is a Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevent new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of a Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes, and clogged pores, and can be used to effectively treat acne, or mask acne, caused by wearing face masks or facial coverings. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories).
- TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
- RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
- DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating acne
- REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
- THE CREATORS OF ADAPALENE: A Retinoid that Fights Acne
- TRAVEL SIZE TOILETRIES: This product is under 3.4 fl oz, making it easy to take with you on your next vacation or trip
Specifications
Active ingredient name
Ingredient preference
Ingredient properties
Scent
Indications
Stop Use Indications
Skin Care Concern
Directions
Instructions
Ingredients
Inactive Ingredients
CARBOMER 940, EDETATE DISODIUM, METHYLPARABEN, POLOXAMER 182, PROPYLENE GLYCOL, PURIFIED WATER AND SODIUM HYDROXIDE. MAY CONTAIN HYDROCHLORIC ACID TO ADJUST PH.
Ingredients
Active Ingredient: Adapalene 0.1% (retinoid)Inactive ingredients: carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. May contain hydrochloric acid to adjust pH.
Active Ingredients
Adapalene
Active Ingredient Name
Active Ingredients: *Adapalene (Retinoid) (0.1 %), Acne Treatment. Inactive Ingredients: Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified Water, Sodium Hydroxide, May Contain Hydrochloric Acid to Adjust pH. *Read consumer information leaflet.
Warnings
State Chemical Disclosure
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Customer ratings & reviews
Reviews summary
Pros
- : Offers great value for the cost.
- : Helps to dry out and clear up pimples rapidly.
- : Helps to clear and prevent breakouts.
- : Convenient to apply with minimal effort.
Neutral
- : Can be drying, but gentle and non-irritating for others.
Customer photos






+360 images
Showing 1-3 of 5,148 reviews
Verified Purchase
This is the best adapalene out there. For me this works better for acne than a script for Tretonin but I don’t try tret gel so ymmv. This is not as harsh as tret and clears up my skin. Paired with a benzoyl peroxide wash this is a great product. Walmart was super fast shipping and has the best price.
Verified Purchase
Using for years and renews skin by peeling it.
Used Retin-A for many years, and more recently a more affordable OTC retinoid/adapalene. They both renew skin by accelerating cell turnover, peeling it. Causes dryness, redness and burning sensation when used too frequently on my older skin. I diminish the side effects by using only 2-3 times a week and frequent moisturizing. I've been told many times I look about 10 yrs younger than my actual age. If too strong for you, start with a lower concentration or use less frequently. Or mix a dot with a compatible serum or moisturizer. As with most acid-based treatments, night time use only!
Verified Purchase
looks good will wait 2 months to see results.
I’ve only been using the Differin Prescription-Strength Retinoid Acne Treatment Gel for a short time so far, but my initial experience has been positive. The quality of the product seems very good—the gel feels smooth and lightweight on the skin, and it absorbs well without leaving any heavy residue. The 15g tube is a convenient size and should last me more than two months with regular use, which makes it quite cost-effective compared to some other treatments I’ve tried. While I haven’t seen dramatic changes yet, I understand that this type of treatment requires patience. The packaging and instructions clearly state that visible results, especially for stubborn blackheads and acne scars, usually take about two months or more. I’m committed to continuing the treatment as directed and am hopeful that it will help clear and prevent acne over time. Overall, it’s a promising product so far—high-quality, fragrance-free, and with a prescription-strength formula that many people trust. I’ll update my review after I’ve used it longer and can see the full effects. For now, I’m encouraged by the initial experience and confident this gel could be a solid part of an acne care routine.
