Prilosec OTC Omeprazole 20mg Acid Reducer, Frequent Heartburn Medicine, Unflavored, 42 Count

Key item features

  • BLOCKS HEARTBURN BEFORE IT STARTS. Starts working on Day 1* to prevent excess acid production, tackling the root cause of your heartburn instead of just masking the symptoms
  • SIMPLE, EFFECTIVE HEARTBURN RELIEF. Just 1 pill each morning is all it takes for 24 hour relief. No more juggling multiple doses or treatments
  • ZERO HEARTBURN* FOR 24 HOURS WITH 1 PILL A DAY. Each pill contains active ingredient omeprazole 20mg, an acid reducer that provides long-lasting, heartburn relief*
  • ALL-DAY & ALL-NIGHT HEARTBURN PROTECTION so you can live life heartburn-free*, unlike Antacids which only last 1 - 3 hours**. **Use all heartburn medications as directed.
Current price is Now $22.00
You save $15.00
was $37.00
52.4 ¢/count
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Sold by meirqbllc
Fulfilled by Walmart
4.405629139072848 stars out of 5, based on 608 seller reviews(4.4)
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Customer ratings & reviews

4.8 out of 5 stars
stars4,095 ratings838 reviews
How item rating is calculated
4.9
5.0
4.1

Reviews summary

Pros

  • : Relieves digestive issues and heartburn symptoms.
  • : Provides extended relief from heartburn symptoms.
  • : Provides 24-hour heartburn relief with one pill.
  • : Offers lower prices than similar retailers.
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Showing 1-3 of 838 reviews

Jun 2, 2026
Patti
Item details
Multipack quantity: 1
Sold and shipped byCornerstone
5 out of 5 stars review

Verified Purchase

This product has saved me from me ftom the misery and pain of terrible heartburn I highly recommend this product. Take it every morning for 2 weeks and after that I would take it once a week and it kept me from suffering

Helpful?3ZUAIPC5CPON10312057
Aug 6, 2024
Ray
5 out of 5 stars review

Verified Purchase

It works.

I've tried them all Prilosec OTC HEARTBURN RELIEF is the one that has worked for me.

Helpful?3ZUAIPC5CPON10312057
Dec 13, 2025
Dewilynn
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

You don't need a prescription to get relief!

I have a prescription for the SAME thing and they want way more at the pharmacy, yet this is the exact ingredient for cheaper. Tried BOTH RX %26 OTC %26 this is Better by far!

Helpful?3ZUAIPC5CPON10312057