

Similac Pro-Total Comfort Powder Baby Formula for Delicate Tummies with 2'-FL HMO for Immune Support, 22.5-oz Tub
Key item features
- Partially hydrolyzed whey protein promotes easy digestion
- Our most gentle formula with prebiotic for immune support
- Has DHA and lutein to support brain & eye development
- No palm olein oil supports excellent calcium absorption for strong bones
- Similac is the #1 infant formula brand fed in hospitals
- No artificial growth hormones§ & non-GMO‖
Specs
- Age range0 - 12 Months
- Primary ingredientWater
- Product linePro-Total Comfort HMO
- Rec. useComfort
- Food formPowders
- SizeTrial
Reviews summary
- : Formula contains ingredients that support immune system development.
- : Formula promotes comfortable digestion.
- : Offers great value for size and quantity.
- : Can be gentle, but may cause gassiness in some users.
- : Can reduce gas, but may not work for all or even increase it in some cases.
How do you want your item?
Popular items in this category
Best selling items that customers love
Similac Pro-Total Comfort Powder Baby Formula, 20.1-oz Tub $32.68
2 optionsAvailable in additional 2 options$3268current price $32.68Options from $32.68 – $133.01Similac Pro-Total Comfort Powder Baby Formula, 20.1-oz Tub
6794.5 out of 5 Stars. 679 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac 360 Total Care Sensitive Baby Formula Powder, Has 5 HMO Prebiotics, 20.1-oz Tub $34.98
4 optionsAvailable in additional 4 options$3498current price $34.98Options from $34.98 – $209.88Similac 360 Total Care Sensitive Baby Formula Powder, Has 5 HMO Prebiotics, 20.1-oz Tub
9864.7 out of 5 Stars. 986 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Pro-Total Comfort Powder Baby Formula, 29.8-oz Value Can $44.98
4 optionsAvailable in additional 4 options$4498current price $44.98Options from $44.98 – $269.88Similac Pro-Total Comfort Powder Baby Formula, 29.8-oz Value Can
22774.4 out of 5 Stars. 2277 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Total Comfort Powder Baby Formula, 12.6-oz Can, Pack of 6 $119.48
$11948current price $119.48Similac Total Comfort Powder Baby Formula, 12.6-oz Can, Pack of 6
834.8 out of 5 Stars. 83 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac Alimentum With 2'-FL HMO, Baby Formula Powder, 12.1-oz Can $38.38
4 optionsAvailable in additional 4 options$3838current price $38.38Options from $38.38 – $230.28Similac Alimentum With 2'-FL HMO, Baby Formula Powder, 12.1-oz Can
20354.3 out of 5 Stars. 2035 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Pro-Total Comfort Ready-to-Feed Baby Formula, 32-fl-oz Bottle $9.79
4 optionsAvailable in additional 4 options$979current price $9.79Options from $9.79 – $58.74Similac Pro-Total Comfort Ready-to-Feed Baby Formula, 32-fl-oz Bottle
2644.7 out of 5 Stars. 264 reviewsSave withShipping, arrives tomorrowSNAP EBT eligibleSimilac Alimentum With 2'-FL HMO, Baby Formula Powder, 12.1-oz Can, Pack of 6 $209.00 $4.32/ea
$20900current price $209.00$4.32/eaSimilac Alimentum With 2'-FL HMO, Baby Formula Powder, 12.1-oz Can, Pack of 6
8004.1 out of 5 Stars. 800 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac Total Comfort Powder Baby Formula, 12.6-oz Can $21.58
4 optionsAvailable in additional 4 options$2158current price $21.58Options from $21.58 – $129.48Similac Total Comfort Powder Baby Formula, 12.6-oz Can
26074.6 out of 5 Stars. 2607 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligible100+ bought since yesterday Similac Total Comfort Powder Baby Formula, 29.8-oz Can $38.97
100+ bought since yesterday
4 optionsAvailable in additional 4 options$3897current price $38.97Options from $38.97 – $233.82Similac Total Comfort Powder Baby Formula, 29.8-oz Can
14024.6 out of 5 Stars. 1402 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 32-fl-oz Bottle, Pack of 6 $95.28
$9528current price $95.28Similac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 32-fl-oz Bottle, Pack of 6
11924.3 out of 5 Stars. 1192 reviewsSave withShipping, arrives in 3+ daysSNAP EBT eligibleSimilac Sensitive Powder Baby Formula, 29.8-oz Can, Pack of 6 $232.82
4 optionsAvailable in additional 4 options$23282current price $232.82More options from $77.94Similac Sensitive Powder Baby Formula, 29.8-oz Can, Pack of 6
49764.6 out of 5 Stars. 4976 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 32-fl-oz Bottle $11.48
4 optionsAvailable in additional 4 options$1148current price $11.48Options from $11.48 – $68.88Similac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 32-fl-oz Bottle
9464.7 out of 5 Stars. 946 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 8-fl-oz Bottle, Pack of 6 $19.98
4 optionsAvailable in additional 4 options$1998current price $19.98Options from $19.98 – $119.88Similac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 8-fl-oz Bottle, Pack of 6
8484.7 out of 5 Stars. 848 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 8-fl-oz Bottle, Pack of 24 $71.88 37.4 ¢/fl oz
$7188current price $71.8837.4 ¢/fl ozSimilac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 8-fl-oz Bottle, Pack of 24
4234.7 out of 5 Stars. 423 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 2-fl-oz Bottle, Pack of 12 $9.88
4 optionsAvailable in additional 4 options$988current price $9.88Options from $9.88 – $59.28Similac 360 Total Care Sensitive Ready-to-Feed Baby Formula, Has 5 HMO Prebiotics, 2-fl-oz Bottle, Pack of 12
8874.7 out of 5 Stars. 887 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligible500+ bought since yesterday Similac Sensitive Powder Baby Formula, 12.5-oz Can $21.28
500+ bought since yesterday
2 optionsAvailable in additional 2 options$2128current price $21.28Options from $21.28 – $42.56Similac Sensitive Powder Baby Formula, 12.5-oz Can
47294.6 out of 5 Stars. 4729 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 8-fl-oz Can, Pack of 6 $15.88
4 optionsAvailable in additional 4 options$1588current price $15.88Options from $15.88 – $95.28Similac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 8-fl-oz Can, Pack of 6
8744.6 out of 5 Stars. 874 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleSimilac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 8-fl-oz Can, Pack of 24 $63.52 $2.65/ea
$6352current price $63.52$2.65/eaSimilac Alimentum With 2'-FL HMO, Ready-to-Feed Baby Formula, 8-fl-oz Can, Pack of 24
7884.1 out of 5 Stars. 788 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac Sensitive Powder Baby Formula, 12.5-oz Can, Pack of 6 $119.68 $9.97/fl oz
$11968current price $119.68$9.97/fl ozSimilac Sensitive Powder Baby Formula, 12.5-oz Can, Pack of 6
15054.5 out of 5 Stars. 1505 reviewsSave withShipping, arrives in 2 daysSNAP EBT eligibleSimilac Sensitive Ready-to-Feed Baby Formula, 32-fl-oz Bottle $9.18
4 optionsAvailable in additional 4 options$918current price $9.18Options from $9.18 – $55.08Similac Sensitive Ready-to-Feed Baby Formula, 32-fl-oz Bottle
20584.6 out of 5 Stars. 2058 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligible
About this item
Product details
- Partially hydrolyzed whey protein promotes easy digestion
- Our most gentle formula with prebiotic for immune support
- Has DHA and lutein to support brain & eye development
- No palm olein oil supports excellent calcium absorption for strong bones
- Similac is the #1 infant formula brand fed in hospitals
- No artificial growth hormones§ & non-GMO‖
Specifications
Brand
Age range
Primary ingredient
Product line
Directions
Instructions
Ingredients
Ingredients
CORN MALTODEXTRIN, WHEY PROTEIN HYDROLYSATE, HIGH OLEIC SAFFLOWER OIL, SUGAR, SOY OIL, COCONUT OIL; LESS THAN 2% OF: SCHIZOCHYTRIUM SP. OIL, M. ALPINA OIL, 2'-FUCOSYLLACTOSE, SHORT-CHAIN FRUCTOOLIGOSAC- CHARIDES, BETA-CAROTENE, LUTEIN, CALCIUM CITRATE, POTASSIUM PHOSPHATE, CALCIUM PHOSPHATE, SALT, MAGNESIUM CHLORIDE, ASCORBIC ACID, CHOLINE CHLORIDE, INOSITOL, POTASSIUM CHLORIDE, SODIUM CITRATE, CALCIUM HYDROXIDE, POTASSIUM CITRATE, CHOLINE BITARTRATE, FERROUS SULFATE, TAURINE, ZINC SULFATE, ASCORBYL PALMITATE, L-CARNITINE, NIACINAMIDE, MIXED TOCOPHEROLS, d-ALPHA-TOCOPHERYL ACETATE, CALCIUM PANTOTHENATE, COPPER SULFATE, VITAMIN A PALMITATE, THIAMINE HYDROCHLORIDE, RIBOFLAVIN, PYRIDOXINE HYDROCHLORIDE, FOLIC ACID, MANGANESE SULFATE, POTASSIUM IODIDE, PHYLLOQUINONE, BIOTIN, SODIUM SELENATE, VITAMIN D3, VITAMIN B12, POTASSIUM HYDROXIDE, AND NUCLEOTIDES (ADENOSINE 5'-MONOPHOSPHATE, CYTIDINE 5'-MONOPHOSPHATE, DISODIUM GUANOSINE 5'-MONOPHOSPHATE, DISODIUM URIDINE 5'-MONOPHOSPHATE), CONTAINS MILK INGREDIENTS.
Warnings
State Chemical Disclosure
More items to consider
Based on what customers bought
Rollback WaterWipes Sensitive Newborn & Baby Wipes, 3-In-1 Cleans, Cares, Protects, 99.9% Water, Unscented & Hypoallergenic, 12 Packs (720 Wipes) $44.97
Rollback
5 optionsAvailable in additional 5 optionsSponsored$4497current price $44.97More options from $7.47WaterWipes Sensitive Newborn & Baby Wipes, 3-In-1 Cleans, Cares, Protects, 99.9% Water, Unscented & Hypoallergenic, 12 Packs (720 Wipes)
106734.7 out of 5 Stars. 10673 reviewsSave withShipping, arrives tomorrow500+ bought since yesterday Huggies Natural Care Cucumber, Aloe and Vitamin E Baby Wipes, Scented, 10 Flip-Top Packs, 560 Total Count (Select for More) $16.97
500+ bought since yesterday
3 optionsAvailable in additional 3 optionsSponsored$1697current price $16.97More options from $6.77Huggies Natural Care Cucumber, Aloe and Vitamin E Baby Wipes, Scented, 10 Flip-Top Packs, 560 Total Count (Select for More)
181264.8 out of 5 Stars. 18126 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowIn 50+ people's carts Pampers Baby Dry Baby Diapers Size 3, 104 Count (Select for More Options) $29.97
In 50+ people's carts
27 optionsAvailable in additional 27 options$2997current price $29.97More options from $10.97Pampers Baby Dry Baby Diapers Size 3, 104 Count (Select for More Options)
364154.5 out of 5 Stars. 36415 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowBest seller Parents Choice Fragrance-Free Baby Wipes, 1200 Count (Select for More Options) $23.38
Best seller
5 optionsAvailable in additional 5 options$2338current price $23.38More options from $0.98Parents Choice Fragrance-Free Baby Wipes, 1200 Count (Select for More Options)
477904.7 out of 5 Stars. 47790 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowBest seller Pampers Pure Diapers Size 5, 132 Count (Select for More Options) $65.47
Best seller
21 optionsAvailable in additional 21 options$6547current price $65.47More options from $29.97Pampers Pure Diapers Size 5, 132 Count (Select for More Options)
46064.7 out of 5 Stars. 4606 reviewsSave withShipping, arrives in 2 daysEnfamil A.R. Powder Baby Formula, Designed to Reduce Frequent Spit-Up in 1 Week, 19.5 Oz Tub $38.88
8 optionsAvailable in additional 8 options$3888current price $38.88More options from $26.97Enfamil A.R. Powder Baby Formula, Designed to Reduce Frequent Spit-Up in 1 Week, 19.5 Oz Tub
94204.7 out of 5 Stars. 9420 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligible1000+ bought since yesterday Huggies Simply Clean Unscented Baby Wipes, 3 Pack, 192 Total Count (Select for More) $6.77
1000+ bought since yesterday
3 optionsAvailable in additional 3 options$677current price $6.77Options from $6.77 – $19.47Huggies Simply Clean Unscented Baby Wipes, 3 Pack, 192 Total Count (Select for More)
82494.7 out of 5 Stars. 8249 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowBest seller Nutramigen with Probiotic LGG Hypoallergenic Powder Baby Formula, 19.8 oz Can $54.48
Best seller
13 optionsAvailable in additional 13 options$5448current price $54.48More options from $41.97Nutramigen with Probiotic LGG Hypoallergenic Powder Baby Formula, 19.8 oz Can
108614.7 out of 5 Stars. 10861 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrowSNAP EBT eligibleRollback Pampers Sensitive Baby Wipes Unscented, 1 Pack, 56 Total Count (Select for More Options) $2.34
Rollback
6 optionsAvailable in additional 6 options$234current price $2.34Options from $2.34 – $39.97Pampers Sensitive Baby Wipes Unscented, 1 Pack, 56 Total Count (Select for More Options)
252104.8 out of 5 Stars. 25210 reviewsSave withPickup tomorrowDelivery todayBest seller Pampers Swaddlers Overnight Zzz Baby Diapers Size 4, 58 Count (Select for More Options) $29.97
Best seller
7 optionsAvailable in additional 7 options$2997current price $29.97Options from $29.97 – $42.47Pampers Swaddlers Overnight Zzz Baby Diapers Size 4, 58 Count (Select for More Options)
54414.6 out of 5 Stars. 5441 reviewsSave withPickup tomorrowDelivery todayShipping, arrives tomorrow1000+ bought since yesterday Gerber Stage 1 Baby Food, Baby Rice Cereal, Gerber Cereal For Baby, Infant Cereal 8 oz $3.48
1000+ bought since yesterday
4 optionsAvailable in additional 4 options$348current price $3.48Options from $3.48 – $20.88Gerber Stage 1 Baby Food, Baby Rice Cereal, Gerber Cereal For Baby, Infant Cereal 8 oz
25874.7 out of 5 Stars. 2587 reviewsSave withPickup tomorrowDelivery todaySNAP EBT eligibleMunchkin® Infant Powdered Formula Dispenser, Blue, Unisex $5.70
$570current price $5.70More options from $4.99Munchkin® Infant Powdered Formula Dispenser, Blue, Unisex
3554.6 out of 5 Stars. 355 reviewsSave withShipping, arrives in 2 daysDr. Brown's Natural Flow Bottle 3-Pack, 8 oz. $28.93
$2893current price $28.93More options from $28.85Dr. Brown's Natural Flow Bottle 3-Pack, 8 oz.
9434.2 out of 5 Stars. 943 reviewsShipping, arrives in 3+ days
Customer ratings & reviews
Reviews summary
- : Formula contains ingredients that support immune system development.
- : Formula promotes comfortable digestion.
- : Offers great value for size and quantity.
- : Can be gentle, but may cause gassiness in some users.
- : Can reduce gas, but may not work for all or even increase it in some cases.
Customer images






+5 images
Showing 1-3 of 756 reviews
Seller Verified Purchase
Great Quality and Excellent Price
Formula often gets negative reviews simply because it's not the right one for your baby!! I have twins with severe silent reflux, the ended up on Alimentum RTF which is fully hydrolocized. Total Comfort is partially hydrolocized - so as the boys have weaned off their reflux medication we've been able to switch to this with great success! Remember parents - IT TAKE 2 FULL WEEKS ON ANY FORMULA TO SEE TRUE RESULTS. Too many parents jump from one formula to another and it's extremely hard on your little ones GI system and you'll never see results.
Need to have
[This review was collected as part of a promotion.] We absolutely adore this product. Packaging is great very informative. Texture is just as any formula you do not need to mix with water. Ingredients are great for your infant. Once open you do need to refrigerate and all must be used within three days. This is great for on the go on vacation or a day over at the grandparents.
So convenient!
[This review was collected as part of a promotion.] We love the gentler formulas offered by Similac, and it's so convenient to have the formula in a ready-to-feed form. It's especially helpful on trips or with those sleepless newborn nights when I have no desire to measure out scoops of powdered formula.
Related pages
- Reguline Formula
- Similac Cans
- Enfamil Water
- Similac Milk
- Similac Sensitive Formula
- Similac Baby Formula
- Similac Routine Baby Formula (Advance, Pro-Advance, Supplementation)
- Enfamil Specialty Liquids
- Similac Baby Formula
- Enfamil Baby Formula
- Enfamil Gentlease, A.R., Reguline, ProSobee, Soy Ready to Use Liquids
- Enfamil Infant Liquid





