Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 30 oz Refill, 4 count
Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 30 oz Refill, 4 count
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Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 30 oz Refill, 4 count

4.8 stars out of 3685 reviews
(4.8)|
3,685 ratings

Key item features

  • NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
  • SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
  • COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
  • TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
  • NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
  • PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
  • JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase. 
  • CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Current price is $251.93$2.10/oz
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Customer ratings & reviews

4.8 out of 5 stars
stars3,685 ratings3,652 reviews
How item rating is calculated
  1. 5 stars87% (3,214)
  2. 4 stars9% (329)
  3. 3 stars2% (71)
  4. 2 stars1% (25)
  5. 1 star1% (46)

Reviews summary

Pros
  • : Formula produces little to no regurgitation.
  • : Formula causes minimal spit up or fussing.
  • : Formula is easy to digest.
  • : Formula allows for seamless switch from breast milk.
  • : Formula is easily absorbed.
Cons
  • : Formula's high cost may be a drawback for some users.
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Showing 1-3 of 3,652 reviews

Jan 19, 2025
anonymous
5 out of 5 stars review

Verified Purchase

very good milk, I transition my son to this milk when he was two months from breastfeeding. I still breastfed him, my milk supply was just low this was a substitute. He took it with ease no digestive problems or crankiness. the other formula he didn't do so well.

Helpful?7EX43PM9GR6Q549319528
reply from Enfamil Customer Care

We are so happy you chose us to help you supplement feedings for your little one, Jennifer! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert

Jan 2, 2026
Angel24
5 out of 5 stars review

Best for newborns

[This review was collected as part of a promotion.] My 7month old baby had this for their first 5 months and it works just as good as breast milk. Our doctor says she's ahead of her development. She's 2 months ahead of her age. I recommend this product 100%

Review from Enfamil
Helpful?7EX43PM9GR6Q549319528
reply from Customer Care

What a great review, Angel24! Thanks! — Marcy, Enfamil Expert

Nov 27, 2025
garabrats
5 out of 5 stars review

The best

This is the first formula we tried, and after trying a few other different ones after, it's the one we ended up going back to. Due to the higher dollar value, we wanted to try other options to see what else might work for our little one who is combination breast/formula, but after one very long month of an upset stomach, we now know that the enfamil inspire is worth every penny. Looking back, we should have never tried anything else!

Review from Enfamil
Helpful?7EX43PM9GR6Q549319528
reply from Customer Care

We are so happy you chose us to help you supplement feedings for your little one, garabrats! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert