

Desitin Daily Defense Baby Diaper Rash Cream, Butt Paste with 13% Zinc Oxide, 16 oz
Key item features
- Desitin Daily Defense Diaper Rash Healing Cream to soothe, treat & prevent baby diaper rash
- The fast-acting formula of this infant diaper rash cream prevents diaper rash from the first use
- #1 choice for diaper rash relief by pediatricians & parents, it is both easy to apply and remove
- It instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
- Made with 13% zinc oxide, it is hypoallergenic and specially formulated for babies' tender skin
- Dermatologist- & Pediatrician-tested, it is clinically shown to provide diaper rash relief
- Paraben-, phthalate-, fragrance and dye-free so it's gentle enough to use at every diaper change
- This skin barrier cream helps seal out wetness to treat diaper rash from the first signs
Specs
- Active ingredientsZinc Oxide 13%
- Active ingredient percentage40
- FormCream
- Ingredient preferenceParaben-Free
- Ingredient propertiesHypoallergenic
- ScentFragrance Free
Reviews summary
- : Offers good value for the amount.
- : Spreads evenly without being too thick.
- : Has a faint or no scent.
- : Has a smooth consistency that spreads evenly.
- : Protects and treats delicate skin with daily use.
- : Prevents and relieves rashes with gentle formulation.
Free 90-day returns
How do you want your item?
More seller options (2)
Similar items you might like
Based on what customers bought
Best seller Boudreaux's Butt Paste Maximum Strength Diaper Rash Cream, Ointment for Infant, 4 oz Tube $6.97 $1.74/oz
Best seller
Sponsored$697current price $6.97$1.74/ozBoudreaux's Butt Paste Maximum Strength Diaper Rash Cream, Ointment for Infant, 4 oz Tube
42074.7 out of 5 Stars. 4207 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowDesitin Maximum Strength Baby Diaper Rash Cream with Zinc Oxide, 16 oz $19.48 Was $22.19 $1.22/oz
Now$1948current price Now $19.48, Was $22.19$22.19$1.22/ozDesitin Maximum Strength Baby Diaper Rash Cream with Zinc Oxide, 16 oz
93814.8 out of 5 Stars. 9381 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowIn 200+ people's carts Aquaphor Baby Healing Ointment, Baby Skin Care and Diaper Rash, 14 oz $18.37
In 200+ people's carts
2 optionsAvailable in additional 2 optionsSponsored$1837current price $18.37Options from $18.37 – $28.21Aquaphor Baby Healing Ointment, Baby Skin Care and Diaper Rash, 14 oz
23844.8 out of 5 Stars. 2384 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow100+ bought since yesterday Equate Diaper Rash Ointment with 40% Zinc Oxide, 16 oz, Compare to Desitin® Maximum Strength 40% Zinc Oxide Diaper Rash Paste $8.94
100+ bought since yesterday
2 optionsAvailable in additional 2 options$894current price $8.94Options from $8.94 – $17.88Equate Diaper Rash Ointment with 40% Zinc Oxide, 16 oz, Compare to Desitin® Maximum Strength 40% Zinc Oxide Diaper Rash Paste
23924.6 out of 5 Stars. 2392 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Desitin Maximum Strength Baby Diaper Rash Cream with Zinc Oxide, 4 oz $6.98
Best seller
2 optionsAvailable in additional 2 options$698current price $6.98Options from $6.98 – $20.94Desitin Maximum Strength Baby Diaper Rash Cream with Zinc Oxide, 4 oz
100414.8 out of 5 Stars. 10041 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Desitin Maximum Strength Baby Diaper Rash Cream, Zinc Oxide, 4.8 oz $7.97
Best seller
2 optionsAvailable in additional 2 options$797current price $7.97Options from $7.97 – $23.91Desitin Maximum Strength Baby Diaper Rash Cream, Zinc Oxide, 4.8 oz
92944.8 out of 5 Stars. 9294 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBoogie Maximum Strength Diaper Rash Cream, Fragrance-Free, 4 fl oz with Spatula Applicator $9.97
2 optionsAvailable in additional 2 optionsSponsored$997current price $9.97Options from $9.97 – $19.94Boogie Maximum Strength Diaper Rash Cream, Fragrance-Free, 4 fl oz with Spatula Applicator
984.7 out of 5 Stars. 98 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Desitin Maximum Strength Baby Diaper Rash Cream, Travel Size, 2 oz $4.98 Was $6.43
Best seller
2 optionsAvailable in additional 2 optionsNow$498current price Now $4.98, Was $6.43$6.43Options from $4.98 – $9.96Desitin Maximum Strength Baby Diaper Rash Cream, Travel Size, 2 oz
62244.7 out of 5 Stars. 6224 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow(2 pack) A+D Treat & Heal Diaper Rash Cream, Zinc Oxide 10%, Easy Spreading Diaper Rash Cream for Baby, 16 oz $28.94
$2894current price $28.94More options from $14.47(2 pack) A+D Treat & Heal Diaper Rash Cream, Zinc Oxide 10%, Easy Spreading Diaper Rash Cream for Baby, 16 oz
744.7 out of 5 Stars. 74 reviewsSave withBest seller Parent's Choice Maximum Strength Diaper Rash Ointment with Zinc Oxide, 4 oz $1.98
Best seller
3 optionsAvailable in additional 3 options$198current price $1.98Options from $1.98 – $7.92Parent's Choice Maximum Strength Diaper Rash Ointment with Zinc Oxide, 4 oz
31594.7 out of 5 Stars. 3159 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowA+D Original Diaper Rash Ointment, 1lb Tub, All Skin Types $14.47
2 optionsAvailable in additional 2 options$1447current price $14.47Options from $14.47 – $28.94A+D Original Diaper Rash Ointment, 1lb Tub, All Skin Types
20074.8 out of 5 Stars. 2007 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowFrida Baby Silicone Diaper Rash Cream Booty Brush, Blue $7.98
$798current price $7.98Frida Baby Silicone Diaper Rash Cream Booty Brush, Blue
1754.7 out of 5 Stars. 175 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBoudreaux's Butt Paste Maximum Strength, Baby Diaper Rash Cream, Infant Ointment, 14 oz Flip-Top $16.97
2 optionsAvailable in additional 2 options$1697current price $16.97Boudreaux's Butt Paste Maximum Strength, Baby Diaper Rash Cream, Infant Ointment, 14 oz Flip-Top
42074.7 out of 5 Stars. 4207 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowA+D Antimicrobial Hydrogel Spray with Hypochlorous Acid - Removes Germs, Helps Heal Rashes & Irritations, Reduces Itch & Pain, Alcohol-Free, Non-Sting Formula, Safe for All Ages, 4oz $6.97
2 optionsAvailable in additional 2 options$697current price $6.97Options from $6.97 – $13.94A+D Antimicrobial Hydrogel Spray with Hypochlorous Acid - Removes Germs, Helps Heal Rashes & Irritations, Reduces Itch & Pain, Alcohol-Free, Non-Sting Formula, Safe for All Ages, 4oz
3114.7 out of 5 Stars. 311 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowAquaphor Baby Diaper Rash Paste, Maximum Strength 40% Zinc Oxide, Diaper Rash Cream, Diaper Rash Ointment, 3.5 oz $7.87
3 optionsAvailable in additional 3 options$787current price $7.87Options from $7.87 – $23.61Aquaphor Baby Diaper Rash Paste, Maximum Strength 40% Zinc Oxide, Diaper Rash Cream, Diaper Rash Ointment, 3.5 oz
10994.7 out of 5 Stars. 1099 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow(2 pack) Parent's Choice Advanced Healing Baby Ointment, 7 oz, Diaper Rash Treatment $11.94
$1194current price $11.94More options from $5.97(2 pack) Parent's Choice Advanced Healing Baby Ointment, 7 oz, Diaper Rash Treatment
774.8 out of 5 Stars. 77 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowAquaphor Baby Diaper Rash Cream with Zinc Oxide, Hypoallergenic, Paraben and Fragrance Free, 3.5 oz $7.47 Was $8.37
3 optionsAvailable in additional 3 optionsNow$747current price Now $7.47, Was $8.37$8.37Options from $7.47 – $22.41Aquaphor Baby Diaper Rash Cream with Zinc Oxide, Hypoallergenic, Paraben and Fragrance Free, 3.5 oz
10604.5 out of 5 Stars. 1060 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBoudreaux's Butt Paste Butt Barrier Diaper Rash Prevention Cream, Ointment for Infant, 4 oz $7.97
2 optionsAvailable in additional 2 options$797current price $7.97Options from $7.97 – $15.94Boudreaux's Butt Paste Butt Barrier Diaper Rash Prevention Cream, Ointment for Infant, 4 oz
354.5 out of 5 Stars. 35 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowA+D Medicated Diaper Rash Cream with Zinc, 4oz $5.47
2 optionsAvailable in additional 2 options$547current price $5.47Options from $5.47 – $10.94A+D Medicated Diaper Rash Cream with Zinc, 4oz
8804.7 out of 5 Stars. 880 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow100+ bought since yesterday Boogie No-Rub Liquid Diaper Rash Spray with Zinc Oxide, 1.7 fl oz $9.97
100+ bought since yesterday
3 optionsAvailable in additional 3 options$997current price $9.97Options from $9.97 – $29.91Boogie No-Rub Liquid Diaper Rash Spray with Zinc Oxide, 1.7 fl oz
13274.7 out of 5 Stars. 1327 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow
About this item
Product details
- Desitin Daily Defense Diaper Rash Healing Cream to soothe, treat & prevent baby diaper rash
- The fast-acting formula of this infant diaper rash cream prevents diaper rash from the first use
- #1 choice for diaper rash relief by pediatricians & parents, it is both easy to apply and remove
- It instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
- Made with 13% zinc oxide, it is hypoallergenic and specially formulated for babies' tender skin
- Dermatologist- & Pediatrician-tested, it is clinically shown to provide diaper rash relief
- Paraben-, phthalate-, fragrance and dye-free so it's gentle enough to use at every diaper change
- This skin barrier cream helps seal out wetness to treat diaper rash from the first signs
Specifications
Active ingredients
Active ingredient percentage
Form
Ingredient preference
Indications
Stop Use Indications
Health Concern
Skin Care Concern
Directions
Instructions
Warranty
Warranty information
Ingredients
Inactive Ingredients
Inactive Ingredients: Water, Mineral Oil, Petrolatum, Beeswax, Dimethicone, Sorbitan Sesquioleate, Microcrystalline Wax, Peg-30 Dipolyhydroxystearate, Aloe Barbadensis Leaf Extract, Glycerin, Tropolone, Tocopheryl Acetate, 1,2-Hexanediol, Caprylyl Glycol, Magnesium Sulfate, Potassium Hydroxide, Phenoxyethanol
Ingredients
Active Ingredient: Zinc Oxide 13% Purpose Skin Protectant Inactive Ingredients: water, mineral oil, petrolatum, beeswax, dimethicone, sorbitan sesquioleate, microcrystalline wax, PEG-30 dipolyhydroxystearate, aloe barbadensis leaf extract, glycerin, tropolone, tocopheryl acetate, 1,2-hexanediol, caprylyl glycol, magnesium sulfate, potassium hydroxide, phenoxyethanol
Active Ingredients
Zinc Oxide 13%
Active Ingredient Name
Zinc Oxide
Warnings
Warning Text
State Chemical Disclosure
Frequently bought together
Desitin Daily Defense Baby Diaper Rash Cream, Butt Paste with 13% Zinc Oxide, 16 oz $15.98 Was $20.97 99.9 ¢/oz

Desitin Daily Defense Baby Diaper Rash Cream, Butt Paste with 13% Zinc Oxide, 16 oz
Dr. Talbot's Silicone Diaper Rash Cream Brush with Suction Base $4.85
Dr. Talbot's Silicone Diaper Rash Cream Brush with Suction Base
Best seller Safety 1st Nursery Care Health & Grooming Kit, Seafoam $21.74

Safety 1st Nursery Care Health & Grooming Kit, Seafoam
Philips Avent Natural Baby Bottle with Natural Response Nipple Newborn Gift Set, SCD837/03 $29.76

Philips Avent Natural Baby Bottle with Natural Response Nipple Newborn Gift Set, SCD837/03
More items to consider
Based on what customers bought
Rollback WaterWipes Sensitive Newborn & Baby Wipes, 3-In-1 Cleans, Cares, Protects, 99.9% Water, Unscented & Hypoallergenic, 12 Packs (720 Wipes) $34.27
Rollback
5 optionsAvailable in additional 5 optionsSponsored$3427current price $34.27More options from $7.47WaterWipes Sensitive Newborn & Baby Wipes, 3-In-1 Cleans, Cares, Protects, 99.9% Water, Unscented & Hypoallergenic, 12 Packs (720 Wipes)
106294.7 out of 5 Stars. 10629 reviewsSave withShipping, arrives tomorrowBest seller Aquaphor Baby Healing Ointment for Teething, Drool and Diaper Rash, Hypoallergenic, 7 oz $12.97
Best seller
Sponsored$1297current price $12.97Aquaphor Baby Healing Ointment for Teething, Drool and Diaper Rash, Hypoallergenic, 7 oz
41484.8 out of 5 Stars. 4148 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Parents Choice Fragrance-Free Baby Wipes, 1200 Count (Select for More Options) $23.38
Best seller
5 optionsAvailable in additional 5 options$2338current price $23.38More options from $0.98Parents Choice Fragrance-Free Baby Wipes, 1200 Count (Select for More Options)
472054.7 out of 5 Stars. 47205 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Huggies Natural Care Sensitive Baby Wipes, Unscented, 6 Pack, 288 Total Count (Select for More) $11.33
Best seller
7 optionsAvailable in additional 7 options$1133current price $11.33More options from $2.27Huggies Natural Care Sensitive Baby Wipes, Unscented, 6 Pack, 288 Total Count (Select for More)
349694.8 out of 5 Stars. 34969 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Johnson's Baby Shampoo with Aloe & Vitamin B5, Tear-Free, 20.3 fl. oz $5.88 Was $9.02 29.0 ¢/fl oz
Best seller
Now$588current price Now $5.88, Was $9.02$9.0229.0 ¢/fl ozJohnson's Baby Shampoo with Aloe & Vitamin B5, Tear-Free, 20.3 fl. oz
55724.6 out of 5 Stars. 5572 reviewsSave withIn 100+ people's carts Eucerin Baby Eczema Relief Moisturizing Body Cream 5 oz $9.78
In 100+ people's carts
2 optionsAvailable in additional 2 options$978current price $9.78Options from $9.78 – $26.41Eucerin Baby Eczema Relief Moisturizing Body Cream 5 oz
10624.7 out of 5 Stars. 1062 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowIn 100+ people's carts Aquaphor Baby Wash & Shampoo, Fragrance Free and Tear Free for Baby's Sensitive Skin, 16.9 fl oz $9.97
In 100+ people's carts
2 optionsAvailable in additional 2 optionsSponsored$997current price $9.97Options from $9.97 – $17.95Aquaphor Baby Wash & Shampoo, Fragrance Free and Tear Free for Baby's Sensitive Skin, 16.9 fl oz
20414.7 out of 5 Stars. 2041 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowCetaphil Baby Moisturizing Aloevera Body Wash and Shampoo, Organic Calendula, 7.8 fl oz $5.87
2 optionsAvailable in additional 2 optionsSponsored$587current price $5.87Options from $5.87 – $11.74Cetaphil Baby Moisturizing Aloevera Body Wash and Shampoo, Organic Calendula, 7.8 fl oz
11154.7 out of 5 Stars. 1115 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowAveeno Baby Eczema Therapy Moisturizing Cream Body Lotion with Oatmeal, 5 oz $9.78 Was $11.44
2 optionsAvailable in additional 2 optionsNow$978current price Now $9.78, Was $11.44$11.44Options from $9.78 – $19.56Aveeno Baby Eczema Therapy Moisturizing Cream Body Lotion with Oatmeal, 5 oz
80734.7 out of 5 Stars. 8073 reviewsSave withShipping, arrives tomorrow500+ bought since yesterday Huggies Natural Care Cucumber, Aloe and Vitamin E Baby Wipes, Scented, 10 Flip-Top Packs, 560 Total Count (Select for More) $16.97
500+ bought since yesterday
3 optionsAvailable in additional 3 options$1697current price $16.97More options from $6.77Huggies Natural Care Cucumber, Aloe and Vitamin E Baby Wipes, Scented, 10 Flip-Top Packs, 560 Total Count (Select for More)
180564.8 out of 5 Stars. 18056 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Aveeno Baby Daily Moisture Body Lotion for Baby and Toddler with Colloidal Oatmeal, 12 fl oz $8.98 74.8 ¢/fl oz
Best seller
$898current price $8.9874.8 ¢/fl ozAveeno Baby Daily Moisture Body Lotion for Baby and Toddler with Colloidal Oatmeal, 12 fl oz
75724.7 out of 5 Stars. 7572 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowJohnson's Baby Bedtime Lotion, NaturalCalm Aromas, 27.1 fl. oz $9.98 36.8 ¢/fl oz
$998current price $9.9836.8 ¢/fl ozJohnson's Baby Bedtime Lotion, NaturalCalm Aromas, 27.1 fl. oz
11454.7 out of 5 Stars. 1145 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowAveeno Baby Daily Moisture Body Lotion, Sensitive Skin, Prebiotic Oatmeal, 18 fl. oz $11.97
2 optionsAvailable in additional 2 options$1197current price $11.97Options from $11.97 – $36.84Aveeno Baby Daily Moisture Body Lotion, Sensitive Skin, Prebiotic Oatmeal, 18 fl. oz
75724.7 out of 5 Stars. 7572 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowJohnson's Moisturizing Bedtime Baby Lotion, Paraben-Free, 27.1 fl. oz $10.98 40.5 ¢/fl oz
$1098current price $10.9840.5 ¢/fl ozJohnson's Moisturizing Bedtime Baby Lotion, Paraben-Free, 27.1 fl. oz
104974.7 out of 5 Stars. 10497 reviewsSave withShipping, arrives tomorrowEucerin Unscented Baby Shampoo and Body Wash, Tear-Free, 13.5 fl oz Pump Bottle $9.78 Was $12.99
2 optionsAvailable in additional 2 optionsNow$978current price Now $9.78, Was $12.99$12.99Options from $9.78 – $17.60Eucerin Unscented Baby Shampoo and Body Wash, Tear-Free, 13.5 fl oz Pump Bottle
7864.7 out of 5 Stars. 786 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow500+ bought since yesterday Huggies Wipes with Aloe & Vitamin E, Unscented, 3 Flip-Top Packs, 168 Total Count (Select for More) $6.77
500+ bought since yesterday
2 optionsAvailable in additional 2 options$677current price $6.77Options from $6.77 – $23.26Huggies Wipes with Aloe & Vitamin E, Unscented, 3 Flip-Top Packs, 168 Total Count (Select for More)
96344.7 out of 5 Stars. 9634 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Johnson's Cornstarch Unisex Powder for Baby and Toddler with Aloe & Vitamin E, 22 oz $6.78 30.8 ¢/oz
Best seller
Sponsored$678current price $6.7830.8 ¢/ozJohnson's Cornstarch Unisex Powder for Baby and Toddler with Aloe & Vitamin E, 22 oz
87134.6 out of 5 Stars. 8713 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowJohnson's Tear-Free Head-To-Toe Baby Body Wash & Shampoo, with Plant-Based Glycerin, 27.1 FL OZ $7.68
2 optionsAvailable in additional 2 optionsSponsored$768current price $7.68Options from $7.68 – $23.04Johnson's Tear-Free Head-To-Toe Baby Body Wash & Shampoo, with Plant-Based Glycerin, 27.1 FL OZ
34744.6 out of 5 Stars. 3474 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Aveeno Baby Daily Moisture Bath Body Wash & Shampoo, Oat Extract, 12 fl oz $8.98
Best seller
2 optionsAvailable in additional 2 options$898current price $8.98Options from $8.98 – $17.96Aveeno Baby Daily Moisture Bath Body Wash & Shampoo, Oat Extract, 12 fl oz
228904.7 out of 5 Stars. 22890 reviewsSave withShipping, arrives tomorrow1000+ bought since yesterday Huggies Natural Care Sensitive Baby Wipes, Unscented, 10 Pack, 560 Total Count (Select for More) $16.97
1000+ bought since yesterday
7 optionsAvailable in additional 7 options$1697current price $16.97More options from $2.27Huggies Natural Care Sensitive Baby Wipes, Unscented, 10 Pack, 560 Total Count (Select for More)
349694.8 out of 5 Stars. 34969 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow
Customer ratings & reviews
Reviews summary
- : Offers good value for the amount.
- : Spreads evenly without being too thick.
- : Has a faint or no scent.
- : Has a smooth consistency that spreads evenly.
- : Protects and treats delicate skin with daily use.
- : Prevents and relieves rashes with gentle formulation.
Customer images






+104 images
Showing 1-3 of 5,121 reviews
Verified Purchase
Walmart Delivery Personnel Steals 75" TV
Product ok. But you don't resolve this : Walmart Delivery Personnel Steals 75" TV in Indianapolis and Walmart Says It's Not Their Responsibility and Doesn't Want to Refund. (Feb 13, 2025 order - order number 2000128-26184814) See the video in YouTube : https://youtu.be/Rk4-ekOnSPQ
I love it because it protects my baby
Desitin Daily Defense is your daily ally to protect your baby's delicate skin and treat diaper rash from the first signs. With a fast-acting and proven formula, this cream instantly creates a protective barrier to relieve discomfort and seal moisture. Recommended by pediatricians and parents, it is ideal to use with each diaper change as a preventive and relief measure.
Destin diaper rush cream
For me it's very crucial to have such reliable cream to avoid diaper rush, especially when baby is newborn, I was using this cream and it's perfect , I used daily several times a day to protect my newborn from diaper rush , and it worked amazingly, my child never had a diaper rush or it was very small that you could not mentioned it , cream is fantastic . Highly recommended it . It does not have a scent and smell so it's so cool, if your newborn and child has an allergies too.
