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Prilosec OTC Omeprazole 20mg Acid Reducer, Frequent Heartburn Medicine, Unflavored, 42 Count

4.8 stars out of 3911 reviews
(4.8)|
3,911 ratings

Key item features

  • BLOCKS HEARTBURN BEFORE IT STARTS. Starts working on Day 1* to prevent excess acid production, tackling the root cause of your heartburn instead of just masking the symptoms
  • SIMPLE, EFFECTIVE HEARTBURN RELIEF. Just 1 pill each morning is all it takes for 24 hour relief. No more juggling multiple doses or treatments
  • ZERO HEARTBURN* FOR 24 HOURS WITH 1 PILL A DAY. Each pill contains active ingredient omeprazole 20mg, an acid reducer that provides long-lasting, heartburn relief*
  • ALL-DAY & ALL-NIGHT HEARTBURN PROTECTION so you can live life heartburn-free*, unlike Antacids which only last 1 - 3 hours**. **Use all heartburn medications as directed.
Current price is $22.9854.7 ¢/count
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Columbus, 43215
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Customer ratings & reviews

4.8 out of 5 stars
stars3,911 ratings826 reviews
How item rating is calculated

Reviews summary

Pros
  • : Provides relief from heartburn for a full day.
  • : Effective with one dose in the morning.
  • : Effectively alleviates acid indigestion and heartburn symptoms.
  • : Allows for normal eating without discomfort.
  • : Available at multiple retailers.
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Showing 1-3 of 826 reviews

Aug 6, 2024
Ray
5 out of 5 stars review

Verified Purchase

It works.

I've tried them all Prilosec OTC HEARTBURN RELIEF is the one that has worked for me.

Helpful?3ZUAIPC5CPON10312057
Dec 13, 2025
Dewilynn
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

You don't need a prescription to get relief!

I have a prescription for the SAME thing and they want way more at the pharmacy, yet this is the exact ingredient for cheaper. Tried BOTH RX %26 OTC %26 this is Better by far!

Helpful?3ZUAIPC5CPON10312057
Feb 5, 2022
Claire
5 out of 5 stars review

Verified Purchase

Favorable

Prilosec gives me relief from GERD like no other OTC product can. However, it does not give me instant relief, like a chewable antacid can sometimes provide. I take Prilosec every day, at the same time, to keep it in my system; and my GERD is totally kept in check!

Helpful?3ZUAIPC5CPON10312057

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