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Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub

4.8 stars out of 3946 reviews
(4.8)|
3,946 ratings

Key item features

  • NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
  • SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
  • COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
  • TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
  • NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
  • PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
  • JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase. 
  • CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Current price is $46.96$2.29/oz
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Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub $46.96 $2.29/oz

Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub
current price $46.96
$2.29/oz

Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub

4.8 out of 5 Stars. 3946 reviews

Philips Avent Natural Glass Baby Bottles with Natural Response Nipples (Medium Flow, Flow 3), 8oz, 3-Pack, SCY913/03 $37.98 $12.66/ea

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Items may be delivered on different dates

Customer ratings & reviews

4.8 out of 5 stars
stars3,946 ratings3,381 reviews
How item rating is calculated

Reviews summary

Pros
  • : Causes minimal spit up or fussing.
  • : Formula is easy to process without discomfort.
  • : Formula produces little to no regurgitation.
  • : Formula transition is smooth and easy to use.
  • : Formula is easy to digest.
Cons
  • : Formula's high cost may be a drawback for some users.
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Showing 1-3 of 3,381 reviews

May 21, 2025
Leticia
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

After breastfeeding for 11 months...

After breastfeeding for 11 months i need it to transition my baby to formula and was a struggle my baby was refusing every formula until i tried this one, i am so grateful for Enfamil Optimum thank you for creating a formula so similar to breastmilk my baby couldn't tell the difference.

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

Thank you for telling us about your experience, Leticia. We are grateful for such a wonderful review! — Marcy, Enfamil Expert

Aug 7, 2025
kaylie
Walmart Associate
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

i little on pricey side but my son was a bf baby and i worked alot and my supply wouldn't keep up with how much he wanted frist try useing and toke to it right away

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

We at Enfamil are so glad you're a part of our family, Kaylie! Thanks for taking time to leave a review! — Abby, Enfamil Expert

May 27, 2025
Sky
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Worth every penny

My son absolutely loves this formula after coming off of breastmilk for 10 months. The first bottle he took right down easily and has not had any sort of issues. Highly recommend this product worth the price.

Helpful?39T1BBBYVMGW49651194
reply from Enfamil Customer Care

We are so happy you chose us to supplement feedings for your little boy, Sky! Thank you for being part of our Enfamil family. — Tasha, Enfamil Expert