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Prilosec OTC Omeprazole 20mg Acid Reducer, Frequent Heartburn Medicine, Unflavored, 42 Count

4.8 stars out of 3861 reviews
(4.8)|
3,861 ratings

Key item features

  • BLOCKS HEARTBURN BEFORE IT STARTS. Starts working on Day 1* to prevent excess acid production, tackling the root cause of your heartburn instead of just masking the symptoms
  • SIMPLE, EFFECTIVE HEARTBURN RELIEF. Just 1 pill each morning is all it takes for 24 hour relief. No more juggling multiple doses or treatments
  • ZERO HEARTBURN* FOR 24 HOURS WITH 1 PILL A DAY. Each pill contains active ingredient omeprazole 20mg, an acid reducer that provides long-lasting, heartburn relief*
  • ALL-DAY & ALL-NIGHT HEARTBURN PROTECTION so you can live life heartburn-free*, unlike Antacids which only last 1 - 3 hours**. **Use all heartburn medications as directed.
Current price is $22.9854.7 ¢/count
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Prilosec OTC Omeprazole 20mg Acid Reducer, Frequent Heartburn Medicine, Unflavored, 42 Count $22.98 54.7 ¢/count

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Customer ratings & reviews

4.8 out of 5 stars
stars3,861 ratings826 reviews
How item rating is calculated

Reviews summary

Pros
  • : Provides relief from heartburn for a full day.
  • : Effective with one dose in the morning.
  • : Effectively alleviates acid indigestion and heartburn symptoms.
  • : Allows for normal eating without discomfort.
  • : Available at multiple retailers.
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Showing 1-3 of 826 reviews

Aug 6, 2024
Ray
5 out of 5 stars review

Verified Purchase

It works.

I've tried them all Prilosec OTC HEARTBURN RELIEF is the one that has worked for me.

Helpful?3ZUAIPC5CPON10312057
Dec 13, 2025
Dewilynn
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

You don't need a prescription to get relief!

I have a prescription for the SAME thing and they want way more at the pharmacy, yet this is the exact ingredient for cheaper. Tried BOTH RX %26 OTC %26 this is Better by far!

Helpful?3ZUAIPC5CPON10312057
Jan 2, 2013
AcidityJane
5 out of 5 stars review

Verified Purchase

The majority of generic OTC products are just as good as the original product, but in this case, that is not so. I have tried the generic brand that is quite a bit less expensive, but it didn't work as well. So I dusted off my billfold and pay the extra price, which is difficult in this day and age. I think the price is too high, it could be reduced by a dollar or two. That would help my billfold and WalMart and Proctor and Gamble would still be making a fortune.

Helpful?3ZUAIPC5CPON10312057