Enfamil Enspire Optimum Powder Baby Formula, With Lactoferrin, Our Closest Formula to Breast Milk, 29 Oz Box, 4 Count
Enfamil Enspire Optimum Powder Baby Formula, With Lactoferrin, Our Closest Formula to Breast Milk, 29 Oz Box, 4 Count
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Enfamil Enspire Optimum Powder Baby Formula, With Lactoferrin, Our Closest Formula to Breast Milk, 29 Oz Box, 4 Count

4.7 stars out of 2631 reviews
(4.7)|
2,631 ratings

Key item features

  • FIRST AND ONLY FORMULA: With lactoferrin, also found in breast milk + colostrum, to support immune health
  • ALL IN ONE COMFORT: Enfamil Enspire Gentlease is scientifically formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • BRAIN BUILDING AND IMMUNE SUPPORT: DHA has been shown to support brain development and Lactoferrin is a protein found in Colostrum that supports the immune system
  • EASY-TO-DIGEST GENTLE PROTEINS: Designed to be easy for developing digestive systems to digest
  • NON-GMO: Enspire is a non-GMO baby formula that is designed to provide complete nutrition for babies through 12 months
  • #1 TRUSTED BRAND: Enfamil is the #1 Trusted Brand for Brain-building & Immune Support
  • PEDIATRICIAN RECOMMENDED: Enfamil is the #1 infant formula brand recommended by pediatricians
  • SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits
  • https://www.walmart.com/m/brands/enfamil
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Customer ratings & reviews

4.7 out of 5 stars
stars2,631 ratings2,623 reviews
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Reviews summary

Pros
  • : Helps babies sleep for extended durations.
  • : Eases stomach issues and aids digestion.
  • : Reduces spit-up and discomfort during feedings.
  • : Reduces gas and fussiness in babies.
Cons
  • : Formula's cost is a significant drawback for many users.
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Showing 1-3 of 2,623 reviews

Jan 7, 2026
VC2024
5 out of 5 stars review

Breastfed to Combo Fed Transition Made Easy

[This review was collected as part of a promotion.] As a mom who decided to breastfeed for my infants first 6 months I was really nervous and skeptical about starting to combo feed my baby with breast milk and formula. This formula was gifted to me by a friend and I am so thankful because my baby took to it so easily. She didn't have any of the typical symptoms like spit up, constipation, etc. This specific formula really put me at ease with the transition in my baby's diet.

Review from Enfamil
Helpful?1WIMZTX2QLHB534902257
reply from Customer Care

We work hard to bring you the very best products. Thanks for leaving us a review, VC2024! — Tasha, Enfamil Expert

Jan 13, 2026
Tate25
5 out of 5 stars review

Great for sensitive stomachs

[This review was collected as part of a promotion.] Started using this product to combo feed baby. It is the best product we could find for our baby with a sensitive stomach. This product helps with spit up, and tummy troubles. We live that it is the closest to breast milk you can find!

Review from Enfamil
Helpful?1WIMZTX2QLHB534902257
reply from Enfamil Costumer Care

Hello! We would love to speak with you directly about your experience with our Enfamil® Optimum™ (Enspire) Gentlease®! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7811611. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert

Dec 12, 2025
Brii
5 out of 5 stars review

Great formula !

[This review was collected as part of a promotion.] When I had my child I tried numerous formulas. She wasnt able to break down the milk without being fussy and having an insane amount of spit ups. The first time we tried the gentleease optimum blend she didnt fuss and had ZERO spit ups. I like that it has a similar protein that's found in breast milk. She loves her formula :)

Review from Enfamil
Helpful?1WIMZTX2QLHB534902257
reply from Customer Care

We are so happy your little one is loving Enfamil, Brii. Thank you for taking time to let us know! — Abby, Enfamil Expert