V monografii vpervye v otechestvennoy literature obobshchayutsya sovremennye literaturnye i sobstvennye dannye avtora o strukturno-funktsional'noy organizatsii izvestnykh signal'nykh sistem i sostavlyayushchikh ikh elementov u svobodnozhivushchikh i paraziticheskikh nizshikh eukariot. Rassmatrivayutsya fosfoinozitidnaya, adenilattsiklaznaya, tirozinkinaznaya sistemy vnutrikletochnoy signalizatsii, a takzhe uchastie v peredache signalov sensorov kletochnoy membrany i sdvigov membrannogo potentsiala. Osoboe vnimanie udelyaetsya analizu putey peredachi stressovykh signalov u eukarioticheskikh mikroorganizmov, issledovaniyu mekhanizmov posttranslyatsionnoy regulyatsii programmiruemykh kletochnykh protsessov, v tom chisle apoptoza. Detal'no rassmatrivayutsya mekhanizmy kal'tsievoy signalizatsii, puti formirovaniya kal'tsievogo signala, analiziruyutsya mekhanizmy vkhoda Sa2+ iz vneshney sredy i mobilizatsii Sa2+ iz vnutrikletochnykh depo.Kniga prednaznachena dlya fiziologov, biokhimikov, protistologov, zanimayushchikhsya problemami vnutrikletochnoy signalizatsii, a takzhe spetsialistov smezhnykh biologicheskikh i meditsinskikh distsiplin. Bibliogr. 1690 nazv. Il. 83. Tabl. 6.
