

Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 30 oz Refill, 4 count
Key item features
- NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
- OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
- SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
- COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
- TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
- NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
- PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
- JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase.
- CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Specs
- Age groupInfant, Newborn
- Rec. useComplete Nutrition
- Shelf life550 days
- Size30 oz
- Count2
- Food formPowders
Reviews summary
Pros
- : Formula's composition mimics breast milk's nutritional profile.
- : Works well as a supplement to breast milk.
- : Suitable for supplementing breast milk or formula transition.
- : Formula is easy to digest.
- : Formula reduces spit-up in most babies.
Cons
- : Formula's high cost is a significant drawback.
- Free shipping
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About this item
Product details
- NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
- OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
- SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
- COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
- TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
- NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
- PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
- JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase.
- CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Specifications
Age group
Rec. use
Shelf life
Size
Directions
Instructions
Safe Handling Instructions
Ingredients
Ingredients
Nonfat milk, lactose, vegetable oil (palm olein, coconut, soy and high oleic sunflower oils), whey protein-lipid concentrate¶ (milk), whey protein concentrate and less than 2%: lactoferrin, galactooligosaccharides#, polydextrose#, Mortierella alpina oil**, Crypthecodinium cohnii oil††, potassium citrate, calcium carbonate, calcium phosphate, sodium chloride, potassium chloride, ferrous sulfate, magnesium oxide, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, soy lecithin, choline chloride, ascorbic acid, niacinamide, calcium pantothenate, riboflavin, thiamin hydrochloride, vitamin D3, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, inositol, vitamin E acetate, vitamin A palmitate, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.¶ A source of MFGM (milk fat globule membrane).# A type of prebiotic.** A source of arachidonic acid (ARA).†† A source of docosahexaenoic acid (DHA).
Warnings
State Chemical Disclosure
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Customer ratings & reviews
Reviews summary
Pros
- : Formula's composition mimics breast milk's nutritional profile.
- : Works well as a supplement to breast milk.
- : Suitable for supplementing breast milk or formula transition.
- : Formula is easy to digest.
- : Formula reduces spit-up in most babies.
Cons
- : Formula's high cost is a significant drawback.
Customer photos






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Showing 1-3 of 3,699 reviews
Verified Purchase
very good milk, I transition my son to this milk when he was two months from breastfeeding. I still breastfed him, my milk supply was just low this was a substitute. He took it with ease no digestive problems or crankiness. the other formula he didn't do so well.
We are so happy you chose us to help you supplement feedings for your little one, Jennifer! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert
Closest thing to breast milk
[This review was collected as part of a promotion.] I used this in unison with breast feeding and my baby could hardly tell the difference. I had a hard time producing the amount of breast milk that I wanted to produce and wanted to make sure that my baby still got all the nutrients he deserved and this formula came in clutch.
We work hard to bring you the very best products. Thanks for leaving us a review! — Tasha, Enfamil Expert
Best for newborns
[This review was collected as part of a promotion.] My 7month old baby had this for their first 5 months and it works just as good as breast milk. Our doctor says she's ahead of her development. She's 2 months ahead of her age. I recommend this product 100%
What a great review, Angel24! Thanks! — Marcy, Enfamil Expert
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