Hero image 0 of THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 5mg, 0 of 9
THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 5mg
Key item features
- Healthy Methylation: Provides essential nutritional support in the form of bioactive, methylated folate (vitamin B9) to promote the body's methylation cycle*
- Cognitive Support: Supports the production of key neurotransmitters like serotonin, melatonin, dopamine, and other natural brain chemicals that regulate mood*
- Nerves & Circulation: Supports healthy blood vessel and nerve function*
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Specs
- Vitamin & supplement typeVitamin Supplements
- Primary ingredientFolate
- Health concernHeart Health
- Serv per cont60
- Dosage1 capsule
- Serving size1 capsule
Current price is USD$68.00
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About this item
Product details
5-MTHF is an active, tissue-ready form of folate. It’s an essential B vitamin that supports healthy methylation, fetal development, and cardiovascular and nerve function.* Since 1984, Thorne has set the standard for the exceptional formulation and quality manufacturing of nutritional supplements. Thorne delivers premium, science-based products, a health diagnostics technology platform, and the latest in medical education. With more than 350 products, Thorne is the most dispensed brand by 30-to 40-year-old healthcare practitioners. Thorne is dedicated to improving the health of our community as well as increasing the knowledge of nutritional health and wellness. Since 2012, Thorne has partnered with educational institutes and local charities to donate more than 1M in products and profits. Thorne products do not contain any unnecessary binders, coatings, disintegrants, fillers, or lubricants (including magnesium stearate) that could impair absorption. Thorne adheres to the current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which test for more than 200 banned substances for elite athletic competitions.
- Healthy Methylation: Provides essential nutritional support in the form of bioactive, methylated folate (vitamin B9) to promote the body's methylation cycle*
- Cognitive Support: Supports the production of key neurotransmitters like serotonin, melatonin, dopamine, and other natural brain chemicals that regulate mood*
- Nerves & Circulation: Supports healthy blood vessel and nerve function*
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
info:
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Specifications
Brand
Thorne
Size
60 Count (Pack of 1)
Enteral medication form
Capsules
Primary ingredient
Folate
Indications
Stop Use Indications
If pregnant, consult your health-care practitioner before using this product. Interactions: 5-methyl-tetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the activity of methotrexate.
Health Concern
Heart Health
Directions
Dosage
1 capsule
Warranty
Warranty information
Please be aware that the warranty terms on items offered for sale by third party Marketplace sellers may differ from those displayed in this section (if any). To confirm warranty terms on an item offered for sale by a third party Marketplace seller, please use the 'Contact seller' feature on the third party Marketplace seller's information page and request the item's warranty terms prior to purchase.
Ingredients
Ingredients
One Capsule Contains: Folate (5 mg as L-5-Methyltetrahydrofolate) 8.3 mg DFE, Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Warnings
Warning Text
legal:*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.,safety:If pregnant, consult your health-care practitioner before using this product. INTERACTIONS: 5-methyl-tetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate.
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Aug 25, 2025
Linda
5 out of 5 stars review
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I will be better able to review when I've taken it 30 days. So far this agrees with my system complete lly.
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Jan 12, 2026
Edgar
5 out of 5 stars review
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Good
Great product. Thank you.
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Apr 1, 2026
Carla
5 out of 5 stars review
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Good for your body.
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