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Sudafed PE Day + Night Maximum Strength Sinus Decongestant, 20 Count
Key item features
- Sudafed PE Sinus Congestion Day + Night Maximum Strength Tablets for powerful symptom relief
- Multi-pack contains 12 Daytime and 8 Nighttime tablets for relief during the day & while you sleep
- The maximum strength medicine helps to temporarily alleviate sinus pressure and sinus congestion
- Relieves nasal congestion due to the common cold, hay fever, or upper respiratory allergies
- Nighttime tablets help relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose
- Both day and night formulas contains 10 mg of the nasal decongestant phenylephrine HCl per tablet
- Each nighttime dose also contains 25 mg of the antihistamine diphenhydramine HCl
- From the Number 1 pharmacist recommended brand among oral OTC decongestants; for adults and children 12+
Specs
- Active ingredient nameSuphedrine
- Over-the-counter medicine typeSinus Relief
- Count per pack20
- FormTablets
- Health concernCold
- Age groupAdult
Reviews summary
Pros
- : Helps users sleep throughout the night.
- : Relieves sinus pressure for a good amount of time.
- : Relieves painful headaches and sinus pressure.
- : Relieves sinus pressure and congestion quickly.
- : Reduces morning congestion and grogginess.
- : Relieves cold and common symptoms.
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Current price is USD$15.6578.3 ¢/count
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4.469767441860465 stars out of 5, based on 215 seller reviews(4.5)215 seller reviews
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$15.27
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About this item
Product details
Get powerful relief from sinus pressure and sinus congestion with Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Tablets. From the Number 1 pharmacist recommended brand among oral OTC decongestants, this multi-pack contains both daytime and nighttime tablets for effective multiple symptom relief. Both the day and night formulas contain 10 milligrams of the nasal decongestant phenylephrine HCl to temporarily relieve sinus congestion and pressure, as well as nasal congestion due to the common cold, hay fever, or upper respiratory allergies. The nighttime decongestant medicine also contains 25 mg of the antihistamine diphenhydramine HCl per tablet, which works to temporarily relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose to help you sleep at night. This maximum strength medicine can be used by adults and children 12 years and older for powerful sinus pressure and congestion relief.
- Sudafed PE Sinus Congestion Day + Night Maximum Strength Tablets for powerful symptom relief
- Multi-pack contains 12 Daytime and 8 Nighttime tablets for relief during the day & while you sleep
- The maximum strength medicine helps to temporarily alleviate sinus pressure and sinus congestion
- Relieves nasal congestion due to the common cold, hay fever, or upper respiratory allergies
- Nighttime tablets help relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose
- Both day and night formulas contains 10 mg of the nasal decongestant phenylephrine HCl per tablet
- Each nighttime dose also contains 25 mg of the antihistamine diphenhydramine HCl
- From the Number 1 pharmacist recommended brand among oral OTC decongestants; for adults and children 12+
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Active ingredient name
Suphedrine
Over-the-counter medicine type
Sinus Relief
Count per pack
20
Form
Tablets
Indications
Stop Use Indications
SUDAFED PE® Sinus Congestion Daytime Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have Heart disease High blood pressure Thyroid disease Diabetes Trouble urinating due to an enlarged prostate glandWhen using this product do not exceed recommended dose Stop use and ask a doctor if Nervousness, dizziness, or sleeplessness occur Symptoms do not improve within 7 days or occur with a feverIf pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) SUDAFED PE® Sinus Congestion Nighttime Do not use To make a child sleepy With any other product containing diphenhydramine, even one used on skin If you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.Ask a doctor before use if you have Heart disease High blood pressure Thyroid disease Diabetes Trouble urinating due to an enlarged prostate gland A breathing problem such as emphysema or chronic bronchitis GlaucomaAsk a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product Do not exceed recommended dose Marked drowsiness may occur Avoid alcoholic drinks Alcohol, sedatives, and tranquilizers may increase drowsiness Be careful when driving a motor vehicle or operating machinery Excitability may occur, especially in childrenStop use and ask a doctor if Nervousness, dizziness, or sleeplessness occur Symptoms do not improve within 7 days or occur with a feverIf pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Health Concern
Cold
Directions
Dosage
SUDAFED PE® Sinus Congestion Daytime Do not take the day and night tablets at the same time. Do not take more than a total of 6 tablets in a 24-hour period. Take only as directed. Important: Read all product information before using. Keep box for important information. Adults and children 12 years and over Take 1 tablet every 4 hours Do not take more than 6 tablets in 24 hoursChildren under 12 years Ask a doctor
Instructions
SUDAFED PE® Sinus Congestion Daytime Do not take the day and night tablets at the same time. Do not take more than a total of 6 tablets in a 24-hour period. Take only as directed. Important: Read all product information before using. Keep box for important information. Adults and children 12 years and over Take 1 tablet every 4 hours Do not take more than 6 tablets in 24 hoursChildren under 12 years Ask a doctor Other information Store between 20-25°C (68-77°F) SUDAFED PE® Sinus Congestion Nighttime Adults and children 12 years and over Take 1 tablet every 4 hours Do not take more than 6 tablets in 24 hoursChildren under 12 years Ask a doctor Other information Store between 20-25°C (68-77°F) Questions or comments? call 1-888-217-2117 (toll-free) or 215-273-8755 (collect)
Warranty
Warranty information
Please be aware that the warranty terms on items offered for sale by third party Marketplace sellers may differ from those displayed in this section (if any). To confirm warranty terms on an item offered for sale by a third party Marketplace seller, please use the 'Contact seller' feature on the third party Marketplace seller's information page and request the item's warranty terms prior to purchase.
Ingredients
Inactive Ingredients
Inactive Ingredients Carnauba Wax, D&C Yellow No. 10 Aluminum Lake, Fd&C Red No. 40 Aluminum Lake, Fd&C Yellow No. 6 Aluminum Lake, Magnesium Stearate, Microcrystalline Cellulose, Modified Starch, Polyethylene Glycol, Polyvinyl Alcohol, Powdered Cellulose, Pregelatinized Starch, Sodium Starch Glycolate, Talc, Titanium Dioxide Sudafed Pe® Sinus Congestion Nighttime Active Ingredients (In Each Tablet) Diphenhydramine Hcl 25 Mg (Antihistamine) Phenylephrine Hcl 10 Mg (Nasal Decongestant) Inactive Ingredients Carnauba Wax, Fd&C Blue No. 1 Aluminum Lake, Magnesium Stearate, Microcrystalline Cellulose, Modified Starch, Polyethylene Glycol, Polyvinyl Alcohol, Powdered Cellulose, Pregelatinized Starch, Sodium Starch Glycolate, Talc, Titanium Dioxide
Ingredients
SUDAFED PE® Sinus Congestion Daytime Active ingredient (in each tablet) Phenylephrine HCl 10 mg (Nasal decongestant) Inactive ingredients carnauba wax, D&C yellow no. 10 aluminum lake, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polyvinyl alcohol, powdered cellulose, pregelatinized starch, sodium starch glycolate, talc, titanium dioxide SUDAFED PE® Sinus Congestion Nighttime Active ingredients (in each tablet) Diphenhydramine HCl 25 mg (Antihistamine) Phenylephrine HCl 10 mg (Nasal decongestant) Inactive ingredients carnauba wax, FD&C blue no. 1 aluminum lake, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polyvinyl alcohol, powdered cellulose, pregelatinized starch, sodium starch glycolate, talc, titanium dioxide
Active Ingredients
Diphenhydramine Phenylephrine
Active Ingredient Name
Suphedrine
Warnings
State Chemical Disclosure
None
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Customer ratings & reviews
How item rating is calculated
Reviews summary
Pros
- : Helps users sleep throughout the night.
- : Relieves sinus pressure for a good amount of time.
- : Relieves painful headaches and sinus pressure.
- : Relieves sinus pressure and congestion quickly.
- : Reduces morning congestion and grogginess.
- : Relieves cold and common symptoms.
Generated by AI
Customer photos
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Showing 1-3 of 132 reviews
Jan 13, 2026
TYWANDA
Top Reviewer
5 out of 5 stars review
Verified Purchase
Great choice
These work really good. i recommend these
Helpful?5QPUM1XNTKTC766306975
Nov 22, 2025
Yolanda
Top Reviewer
5 out of 5 stars review
Verified Purchase
Red or blue pills
Blue pills are best. Red pills are useless
Helpful?5QPUM1XNTKTC766306975
Mar 2, 2026
Marlene
Top Reviewer
5 out of 5 stars review
Verified Purchase
Does the job?
Helpful?5QPUM1XNTKTC766306975
