(4 pack) Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub

Key item features

  • OUR CLOSEST FORMULA TO BREAST MILK: Enspire Optimum is Enfamil’s closest formula to breast milk with lactoferrin, found in colostrum + breast milk, and Dual HMOs
  • PROTEIN YOUR BABY NEEDS: Enspire Optimum has lactoferrin; an important protein in breast milk + colostrum that aids in iron absorption and supports baby’s immune system
  • EXCLUSIVE HuMO6 IMMUNE BLEND: Formula designed from breast milk with key components, such as 2’-FL HMO, LNnT HMO, Vitamin C, Vitamin E, Zinc, and Selenium
  • PEACE OF MIND: Enspire Optimum has NO artificial growth hormones, NO artificial colors or flavors, and NON-GMO, designed for complete nutrition for babies through 12 months
  • TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Trusted Brand for Brain-Building & Immune Support
  • SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits
Current price is $187.84$2.29/oz
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This item includes:

  • 4-pack of Enfamil Optimum (Enspire) Powder Baby Formula, Our Closest to Breast Milk, 20.5 oz Tub
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Customer ratings & reviews

4.7 out of 5 stars
stars4,110 ratings3,424 reviews
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Reviews summary

Pros

  • : Formula's nutritional profile and consistency mirror breast milk's.
  • : Works as a supplement to breastmilk.
  • : Formula transition is smooth and easy.
  • : Formula causes minimal spit up and gas.
  • : Formula reduces spit-up in most babies.

Cons

  • : Formula's high cost is a significant drawback.
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Showing 1-3 of 3,424 reviews

Feb 14, 2026
Shelby
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Had to start supplementing and we chose this formula. I love the nutrition value and how close this formula is to breast milk. The transition was gentle on my little one's tummy. We will be using this formula permanently for supplementation.

Helpful?39T1BBBYVMGW16495664559
reply from Enfamil Customer Care

We are so happy you chose us to help you supplement feedings for your little one, Shelby! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert

Aug 7, 2025
kaylie
Walmart Associate
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

i little on pricey side but my son was a bf baby and i worked alot and my supply wouldn't keep up with how much he wanted frist try useing and toke to it right away

Helpful?39T1BBBYVMGW16495664559
reply from Enfamil Customer Care

We at Enfamil are so glad you're a part of our family, Kaylie! Thanks for taking time to leave a review! — Abby, Enfamil Expert

May 21, 2025
Leticia
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

After breastfeeding for 11 months...

After breastfeeding for 11 months i need it to transition my baby to formula and was a struggle my baby was refusing every formula until i tried this one, i am so grateful for Enfamil Optimum thank you for creating a formula so similar to breastmilk my baby couldn't tell the difference.

Helpful?39T1BBBYVMGW16495664559
reply from Enfamil Customer Care

Thank you for telling us about your experience, Leticia. We are grateful for such a wonderful review! — Marcy, Enfamil Expert