An unprecedented review of our current knowledge of the neuroinflammatory mediators and cells involved in neurodegenerative diseases. Beginning with a detailed review of our current concepts of which biochemical mediators are involved in neuronal loss and the mechanisms of cell death the distinguished contributors critically examine those areas of current research involved in the design of specific pharmacological agents to inhibit at defined points in the neuroinflammatory cascade. They also address the molecular cellular and disease model actions of first-generation agents as well as the potential clinical relevance to AIDS-related dementia Alzheimer's disease amyotropic lateral sclerosis (ALS) Down's syndrome Huntington's disease multiple sclerosis Parkinson's disease and stroke. CONDITION – USED: Books sold are in GOOD or better condition. Good Condition: Minimal damage to the cover, dust jacket may not be included, minimal wear to binding, most of the pages undamaged(e.g., minimal creases or tears), highlighting / underlining acceptable on books as long as the text is readable and markings are not excessive, no missing pages. May be a former library book, with usual treatments(e.g., mylar covers, call stickers, stamps, card pockets, barcodes, or remainder marks). Extra components, such as CDs, DVDs, figurines, or access codes are not included. ISBN: 9780896034167 ISBN10: 089603416X Contributors: Wood, Paul L.,