Hero image 0 of THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules, 0 of 9
THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
Key item features
- Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
- Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
- Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Specs
- Vitamin & supplement typeVitamin Supplements
- Primary ingredientVitamin B-Complex, Folate
- Health concernHeart Health, General Health & Wellness
- Serv per cont30
- Serving size3 Capsules
- Enteral medication formCapsules
Current price is USD$62.00
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About this item
Product details
More concentrated methylation support. Since 1984, Thorne has set the standard for the exceptional formulation and quality manufacturing of nutritional supplements. Thorne delivers premium, science-based products, a health diagnostics technology platform, and the latest in medical education. With more than 350 products, Thorne is the most dispensed brand by 30-to 40-year-old health-care practitioners. Thorne is dedicated to improving the health of our community as well as increasing the knowledge of nutritional health and wellness. Since 2012, Thorne has partnered with educational institutes and local charities to donate more than 1M in products and profits.Thorne products do not contain any unnecessary binders, coatings, disintegrants, fillers, or lubricants (including magnesium stearate) that could impair absorption. Thorne adheres to the current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which test for more than 200 banned substances for elite athletic competitions.
- Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
- Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
- Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Brand
Thorne
Size
90 Capsules
Enteral medication form
Capsules
Primary ingredient
Vitamin B-Complex, Folate
Indications
Stop Use Indications
If pregnant, consult your health-care practitioner before using this product. 5-methyl-tetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Health Concern
Heart Health General Health & Wellness
Skin Care Concern
Dryness
Directions
Dosage
Take 1-3 capsules daily or as recommended by a healthcare practitioner.
Warranty
Warranty information
None
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Please be aware that the warranty terms on items offered for sale by third party Marketplace sellers may differ from those displayed in this section (if any). To confirm warranty terms on an item offered for sale by a third party Marketplace seller, please use the 'Contact seller' feature on the third party Marketplace seller's information page and request the item's warranty terms prior to purchase.
Ingredients
Ingredients
Riboflavin (as Riboflavin 5'-Phosphate Sodium) 90 mg, Vitamin B6 (as Pyridoxal 5'-Phosphate) 45 mg, Folate (3 mg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 5 mg DFE, Vitamin B12 (as Methylcobalamin) 3 mg, Betaine Anhydrous (Trimethylglycine) 1.8 g Other Ingredients: Hypromellose (derived from cellulose) capsule, Calcium Citrate, Calcium Laurate.
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Showing 1-3 of 83 reviews
Dec 23, 2025
J
5 out of 5 stars review
Verified Purchase
Recommend Highly
Seller is Excellent. Product is just what my doctor ordered. Excellent Product %26 Seller. Will BUY AGAIN %26 I Highly recommended THORNE - Methyl-Guard Plus - Active folate (5-MTHF) to others. Tolerate this product well, no taste or fizziness.
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Jun 9, 2025
mary
5 out of 5 stars review
Verified Purchase
Because of MTHFR gene differenial, I must take methylated B vitamin complex 2x day per neuro doc. i have tried many brands over many years. in my humble opinion, Thorne digests easiest, thereby providing me w said B vitamins.
Helpful?6ZFU6103YF6O148311295
Jan 29, 2026
Elaine
5 out of 5 stars review
Verified Purchase
The recipient of my gift was very happy with the quality
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