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Excedrin Extra Strength Pain Relief Caplets for Headache Relief, Acetaminophen 250Mg, Aspirin 250Mg, Caffeine 65Mg, Pain Reliever, 100 Count

4.8 stars out of 9793 reviews
(4.8)|
9,793 ratings

Key item features

  • One bottle of 100 Excedrin Extra Strength Caplets
  • Extra strength pain reliever that relieves pain associated with headache, colds, menstrual cramps, tooth pain, muscle pain and arthritis
  • Excedrin Extra Strength works in 3 ways: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance pain relief effect
  • Pain medicine that is a clinically proven headache pain reliever
  • Excedrin Extra Strength caplets contain two pain relievers and a booster for enhanced effect
  • Pain reliever available in convenient caplet form
  • For some, headache relief can start in 15 minutes
  • HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
Current price is $12.7812.8 ¢/count
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Customer ratings & reviews

4.8 out of 5 stars
stars9,793 ratings6,471 reviews
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Reviews summary

Pros
  • : Relieves headaches within 15-30 minutes.
  • : Offers large quantity at a reasonable cost.
  • : Provides quick relief from various types of pain.
  • : Pills are a comfortable size to swallow.
  • : Pill has no noticeable scent or odor.
  • : Has a notable amount of caffeine to enhance effectiveness.
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Showing 1-3 of 6,471 reviews

Oct 28, 2025
Mel
Item details
Count per pack: 24
5 out of 5 stars review

Verified Purchase

Wow! I rarely ever get headaches, but got a 2 day migraine out of nowhere. A friend suggested this and within the hour I could already feel relief. By my 2nd dose my severe migraine was completely gone. Great item at a reasonable price. Everyone is different; this was just my personal great experience.

Helpful?3RDVD0L61F4J10294261
Dec 9, 2025
Patricia
Item details
Count per pack: 200
5 out of 5 stars review

Verified Purchase

This combination of medications works better for my pain management than any other OTC or prescription medication I have ever used. Have had a lot of falls and injuries over the years (I am 77) and I have relied on it all of my adult life. It also works for headaches. I take it as prescribed and don't expect it to completely relieve pain…nothing does. But it enables me to do what I need to do and keep functioning better than without.

Helpful?3RDVD0L61F4J10294261
Sep 7, 2025
Kris
Item details
Count per pack: 100
5 out of 5 stars review

Verified Purchase

Excedrin doesn't disappoint

Nothing else on earth could come close to the power of excedrin. Knocked out headaches %26 body pains like no other. I've tried many different store brands to save a few dollars but ended up wasting money cuz they never work. The caffeine is also a pickup when I'm a bit sluggish.

Helpful?3RDVD0L61F4J10294261