Pain Relievers

Self-care up to 40% off
All your relaxation musts & more.Shop now
Excedrin and Tylenol pain relief meds.

Headache relief from trusted brands

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Aleve and Advil pain meds are shown alongside ThermaCare‘s heat therapy patches.

Ease neck & back pain

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Salonpas patches and Biofreeze gel for pain relief.

Soothe sore muscles

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Unisom sleep tabs and Vicks ZzzQuil in the flavor grape.

Calming sleep aids

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Tylenol’s pain meds and Voltaren topical pain relief gel.

Arthritis care, for less

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Flige’s portable massager is shown alongside pain relief supplements from Force Factor and NOW.

Relief for all kinds of pain

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Ease discomfort your way

Get supplements, massagers & more.

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TLC for your cycle

Find heating pads, meds & more.

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A red plush lobster, Pamprin multisymptom and Midol Complete pain relievers.

Support for that time of the month

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Similasan earache relief, Lipo Flavonoid relief drops and Hyland’s earache drops.

From ear drops to wax removal

Relief for ear pain & discomfort

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Everyday ear care

Treat aches, clogs & more.

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Comfytemp cold compress

Cold packs that cover the needs of all parts of the body

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Shop all pain management

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Equate Ibuprofen Pain Reliever and Fever Reducer Tablets, 200 mg, 500 Count
Equate Ibuprofen Pain Reliever and Fever Reducer Tablets, 200 mg, 500 Count
current price $7.98
1.6 ¢/count
Equate Ibuprofen Pain Reliever and Fever Reducer Tablets, 200 mg, 500 Count
4.8 out of 5 Stars. 41907 reviews
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AZO Cranberry Urinary Tract Health Supplement, Helps Cleanse & Protect for Reduced UTIs, 120 Count
AZO Cranberry Urinary Tract Health Supplement, Helps Cleanse & Protect for Reduced UTIs, 120 Count
current price $14.48
12.1 ¢/count
AZO Cranberry Urinary Tract Health Supplement, Helps Cleanse & Protect for Reduced UTIs, 120 Count
4.8 out of 5 Stars. 3243 reviews
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Equate Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, 500 Count (2x250 Count), Compare to Advil Tablets Active Ingredient
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Equate Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, 500 Count (2x250 Count), Compare to Advil Tablets Active Ingredient
current price $7.98
1.6 ¢/count
Equate Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, 500 Count (2x250 Count), Compare to Advil Tablets Active Ingredient
4.8 out of 5 Stars. 41907 reviews
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Tylenol Extra Strength 500mg Acetaminophen Caplets, Travel Size, 10 Count
Tylenol Extra Strength 500mg Acetaminophen Caplets, Travel Size, 10 Count
current price $2.00
20.0 ¢/count
Tylenol Extra Strength 500mg Acetaminophen Caplets, Travel Size, 10 Count
4.7 out of 5 Stars. 8916 reviews
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Tylenol Extra Strength 500 mg Acetaminophen Rapid Release Gels, 100 Count
Tylenol Extra Strength 500 mg Acetaminophen Rapid Release Gels, 100 Count
current price $12.47, Was $22.14
12.5 ¢/count
Tylenol Extra Strength 500 mg Acetaminophen Rapid Release Gels, 100 Count
4.8 out of 5 Stars. 29009 reviews
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Equate Extra Strength Acetaminophen Pain Reliever Caplets, 500 mg, 500 Count, 2 Pack
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Equate Extra Strength Acetaminophen Pain Reliever Caplets, 500 mg, 500 Count, 2 Pack
current price $14.96
1.5 ¢/count
Equate Extra Strength Acetaminophen Pain Reliever Caplets, 500 mg, 500 Count, 2 Pack
4.8 out of 5 Stars. 23323 reviews
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Equate Extra Strength Pain Reliever Acetaminophen Caplets, 500mg, Pain Reliever/Fever Reducer, 200 Count, Compare to Tylenol Extra Strength Active Ingredient
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Equate Extra Strength Pain Reliever Acetaminophen Caplets, 500mg, Pain Reliever/Fever Reducer, 200 Count, Compare to Tylenol Extra Strength Active Ingredient
current price $3.94
2.0 ¢/count
Equate Extra Strength Pain Reliever Acetaminophen Caplets, 500mg, Pain Reliever/Fever Reducer, 200 Count, Compare to Tylenol Extra Strength Active Ingredient
4.8 out of 5 Stars. 23323 reviews
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Children's Motrin Ibuprofen Kids Medicine, Berry Flavored, 8 fl. oz
Children's Motrin Ibuprofen Kids Medicine, Berry Flavored, 8 fl. oz
current price $11.97
$1.50/fl oz
Children's Motrin Ibuprofen Kids Medicine, Berry Flavored, 8 fl. oz
4.8 out of 5 Stars. 3853 reviews
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Voltaren Topical Arthritis Medicine Gel Pain Reliever for Arthritis,1.7 Oz
Voltaren Topical Arthritis Medicine Gel Pain Reliever for Arthritis,1.7 Oz
current price $11.98
$7.05/oz
Voltaren Topical Arthritis Medicine Gel Pain Reliever for Arthritis,1.7 Oz
4.5 out of 5 Stars. 21315 reviews
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Voltaren Arthritis Pain Relief Gel Diclofenac Sodium 1% NSAID 100g
Voltaren Arthritis Pain Relief Gel Diclofenac Sodium 1% NSAID 100g
current price $19.98
$5.71/oz
Voltaren Arthritis Pain Relief Gel Diclofenac Sodium 1% NSAID 100g
4.5 out of 5 Stars. 21315 reviews
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Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 300 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
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Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 300 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
current price $15.48
5.2 ¢/count
Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 300 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
4.8 out of 5 Stars. 9986 reviews
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Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 80 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
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Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 80 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
current price $6.47
8.1 ¢/count
Equate Ibuprofen Mini Liquid Filled Softgel Capsules, 200 mg, Pain Relief & Fever Reducer, 80 Count, Compare to Advil LIQUI-GELS Minis Active Ingredient
4.8 out of 5 Stars. 9986 reviews
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Vicks DayQuil and NyQuil Severe Cold and Flu Liquid, Cold and Flu Medicine for Adults, 2x12 Fl oz
Vicks DayQuil and NyQuil Severe Cold and Flu Liquid, Cold and Flu Medicine for Adults, 2x12 Fl oz
current price $21.97
91.5 ¢/fl oz
Vicks DayQuil and NyQuil Severe Cold and Flu Liquid, Cold and Flu Medicine for Adults, 2x12 Fl oz
4.7 out of 5 Stars. 6114 reviews
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Advil Pain Relief and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 100 Count
Advil Pain Relief and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 100 Count
current price $10.98
11.0 ¢/count
Advil Pain Relief and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 100 Count
4.7 out of 5 Stars. 15103 reviews
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Advil Pain Relievers and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 50 Count
Advil Pain Relievers and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 50 Count
current price $7.28
14.6 ¢/count
Advil Pain Relievers and Fever Reducer Coated Tablets, 200 Mg Ibuprofen, 50 Count
4.7 out of 5 Stars. 15103 reviews
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Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 24 Count
Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 24 Count
current price $5.97
24.9 ¢/count
Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 24 Count
4.7 out of 5 Stars. 15012 reviews
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Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 100 Count
Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 100 Count
current price $13.97, Was $17.56
14.0 ¢/count
Tylenol PM Extra Strength Pain Reliever & Sleep Aid Caplets, 100 Count
4.7 out of 5 Stars. 15012 reviews
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Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 24 Count
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 24 Count
current price $4.97
20.7 ¢/count
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 24 Count
4.8 out of 5 Stars. 12010 reviews
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Equate Witch Hazel Flushable Hemorrhoidal Medicated Wipes, 48 Count
Equate Witch Hazel Flushable Hemorrhoidal Medicated Wipes, 48 Count
current price $4.24
$8.83/per 100 count
Equate Witch Hazel Flushable Hemorrhoidal Medicated Wipes, 48 Count
4.6 out of 5 Stars. 2724 reviews
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Equate Maximum Strength Urinary Pain Relief Phenazopyridine Tablets, 99.5 mg, 24 Count, Compare to AZO Urinary Pain Relief Maximum Strength Active Ingredient
Equate Maximum Strength Urinary Pain Relief Phenazopyridine Tablets, 99.5 mg, 24 Count, Compare to AZO Urinary Pain Relief Maximum Strength Active Ingredient
current price $5.48
22.8 ¢/count
Equate Maximum Strength Urinary Pain Relief Phenazopyridine Tablets, 99.5 mg, 24 Count, Compare to AZO Urinary Pain Relief Maximum Strength Active Ingredient
4.7 out of 5 Stars. 3388 reviews
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Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
current price $12.78
12.8 ¢/count
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
4.8 out of 5 Stars. 12010 reviews
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Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 32 Count, Compare to Unisom SleepGels Active Ingredient
Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 32 Count, Compare to Unisom SleepGels Active Ingredient
current price $4.98
15.6 ¢/count
Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 32 Count, Compare to Unisom SleepGels Active Ingredient
4.6 out of 5 Stars. 11469 reviews
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Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 100 Count, Compare to Unisom SleepGels Active Ingredient
Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 100 Count, Compare to Unisom SleepGels Active Ingredient
current price $9.97
10.0 ¢/count
Equate Maximum Strength Nighttime Sleep-Aid Diphenhydramine HCl Sleep Support Softgels, 50 mg, 100 Count, Compare to Unisom SleepGels Active Ingredient
4.6 out of 5 Stars. 11469 reviews
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Equate Children's Ibuprofen Oral Suspension 100 mg per 5 mL, Grape Flavor, 4 Fluid ounce (US)
Equate Children's Ibuprofen Oral Suspension 100 mg per 5 mL, Grape Flavor, 4 Fluid ounce (US)
current price $4.16
$1.04/fl oz
Equate Children's Ibuprofen Oral Suspension 100 mg per 5 mL, Grape Flavor, 4 Fluid ounce (US)
4.8 out of 5 Stars. 4378 reviews
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Infants' Tylenol Acetaminophen Medicine, Dye-Free Cherry, 1 fl. oz
Infants' Tylenol Acetaminophen Medicine, Dye-Free Cherry, 1 fl. oz
current price $6.77
$6.77/fl oz
Infants' Tylenol Acetaminophen Medicine, Dye-Free Cherry, 1 fl. oz
4.8 out of 5 Stars. 2566 reviews
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Equate Children's Ibuprofen Oral Suspension, 100 mg, Bubble Gum Flavor, Ages 2 to 11 Years, 8 fl oz, Compare to Children's Motrin Active Ingredient
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Equate Children's Ibuprofen Oral Suspension, 100 mg, Bubble Gum Flavor, Ages 2 to 11 Years, 8 fl oz, Compare to Children's Motrin Active Ingredient
current price $6.48, Was $7.24
81.0 ¢/fl oz
Equate Children's Ibuprofen Oral Suspension, 100 mg, Bubble Gum Flavor, Ages 2 to 11 Years, 8 fl oz, Compare to Children's Motrin Active Ingredient
4.8 out of 5 Stars. 4378 reviews
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Tylenol Extra Strength 500mg Acetaminophen Caplets, Value Size, 100 Count
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Tylenol Extra Strength 500mg Acetaminophen Caplets, Value Size, 100 Count
current price $10.97
11.0 ¢/count
Tylenol Extra Strength 500mg Acetaminophen Caplets, Value Size, 100 Count
4.8 out of 5 Stars. 26844 reviews
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Children's Tylenol Pain + Fever Medicine, Dye-Free, Cherry, 8 fl. oz
Children's Tylenol Pain + Fever Medicine, Dye-Free, Cherry, 8 fl. oz
current price $11.47
$1.43/fl oz
Children's Tylenol Pain + Fever Medicine, Dye-Free, Cherry, 8 fl. oz
4.8 out of 5 Stars. 10242 reviews
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Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 12 Fl oz
Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 12 Fl oz
current price $9.96
83.0 ¢/fl oz
Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 12 Fl oz
4.7 out of 5 Stars. 5964 reviews
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Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 24 Fl oz
Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 24 Fl oz
current price $15.97
66.5 ¢/fl oz
Vicks ZzzQuil Nighttime Sleep Aid Liquid, Diphenhydramine HCI 50mg, Warming Berry, 24 Fl oz
4.7 out of 5 Stars. 5964 reviews
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Tylenol Cold + Flu Severe Caplets for Multi-Symptom Relief, 24 Count.
Tylenol Cold + Flu Severe Caplets for Multi-Symptom Relief, 24 Count.
current price $7.67
32.0 ¢/count
Tylenol Cold + Flu Severe Caplets for Multi-Symptom Relief, 24 Count.
4.7 out of 5 Stars. 2560 reviews
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Vicks NyQuil Cold and Flu Liquid, Nighttime Cold Medicine for Adults, Original, 12 fl oz
Vicks NyQuil Cold and Flu Liquid, Nighttime Cold Medicine for Adults, Original, 12 fl oz
current price $10.97
91.4 ¢/fl oz
Vicks NyQuil Cold and Flu Liquid, Nighttime Cold Medicine for Adults, Original, 12 fl oz
4.8 out of 5 Stars. 3143 reviews
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Vicks VapoRub, Topical Chest Rub & Analgesic Ointment, 1.76 oz
Vicks VapoRub, Topical Chest Rub & Analgesic Ointment, 1.76 oz
current price $7.47
$4.24/oz
Vicks VapoRub, Topical Chest Rub & Analgesic Ointment, 1.76 oz
4.8 out of 5 Stars. 5758 reviews
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Tylenol 8 Hour Arthritis & Joint Pain Acetaminophen Caplets, 100 Count
Tylenol 8 Hour Arthritis & Joint Pain Acetaminophen Caplets, 100 Count
current price $12.47
12.5 ¢/count
Tylenol 8 Hour Arthritis & Joint Pain Acetaminophen Caplets, 100 Count
4.8 out of 5 Stars. 21560 reviews
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Equate Non-Drowsy Severe Sinus Congestion & Pain Caplets, 24 Count
Equate Non-Drowsy Severe Sinus Congestion & Pain Caplets, 24 Count
current price $4.42
18.4 ¢/count
Equate Non-Drowsy Severe Sinus Congestion & Pain Caplets, 24 Count
4.6 out of 5 Stars. 5832 reviews
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Advil Dual Action Pain Relievers Coated Caplets, 125Mg Ibuprofen and 250Mg Acetaminophen, 72 Count
Advil Dual Action Pain Relievers Coated Caplets, 125Mg Ibuprofen and 250Mg Acetaminophen, 72 Count
current price $10.98
15.3 ¢/count
Advil Dual Action Pain Relievers Coated Caplets, 125Mg Ibuprofen and 250Mg Acetaminophen, 72 Count
4.8 out of 5 Stars. 14890 reviews
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Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Relief Caplets, 24 Count
Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Relief Caplets, 24 Count
current price $7.64
31.8 ¢/count
Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Relief Caplets, 24 Count
4.7 out of 5 Stars. 3072 reviews
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Equate Sore Throat and Cough Relief Menthol Cough Drops, Honey Lemon Flavor, 160 Count
Equate Sore Throat and Cough Relief Menthol Cough Drops, Honey Lemon Flavor, 160 Count
current price $4.48
2.8 ¢/count
Equate Sore Throat and Cough Relief Menthol Cough Drops, Honey Lemon Flavor, 160 Count
4.7 out of 5 Stars. 7133 reviews
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Vicks Vapo Shower Tablets, Menthol Scent Soothing Non-Medicated Shower Steamers, 3 Count
Vicks Vapo Shower Tablets, Menthol Scent Soothing Non-Medicated Shower Steamers, 3 Count
current price $6.47, Was $14.08
$2.16/count
Vicks Vapo Shower Tablets, Menthol Scent Soothing Non-Medicated Shower Steamers, 3 Count
4.4 out of 5 Stars. 2051 reviews
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Advil Pain Reliever and Fever Reducer Coated Tablets, Ibuprofen 200Mg Pain Relief, 10 Count
Advil Pain Reliever and Fever Reducer Coated Tablets, Ibuprofen 200Mg Pain Relief, 10 Count
current price $2.00
20.0 ¢/count
Advil Pain Reliever and Fever Reducer Coated Tablets, Ibuprofen 200Mg Pain Relief, 10 Count
4.7 out of 5 Stars. 9596 reviews
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About Pain Relievers - Walmart.com

What can I do if a fever does not respond to ibuprofen?

If your fever is not responding well to ibuprofen, you might want to try alternating ibuprofen and acetaminophen. Take a dose of ibuprofen followed by acetaminophen four hours later and repeat until your fever drops. If your fever does not respond to alternating pain medications, consult a doctor.

What type of over-the-counter pain reliever works to relieve arthritis pain?

Any over-the-counter anti-inflammatory pain reliever should provide relief from arthritis pain. Acetaminophen, naproxen, or ibuprofen are all non-steroidal anti-inflammatory drugs, or NSAIDs, and any of these should work. Try each and see which works best for you as it sometimes comes down to personal preference.

Does aspirin prevent heart attacks?

Low doses of aspirin have been shown as being effective in helping to prevent heart attack or stroke if you are at an increased risk for such conditions. A doctor should consult with you on the appropriate dosage and frequency of taking the medication. Work with a doctor to discuss any potential side effects and benefits before starting an aspirin regime.