Vetoquinol Zylkene Calming Behavior Support Supplement, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief, Dog or Cat, 22-65lbs, 225mg, 120ct
Vetoquinol Zylkene Calming Behavior Support Supplement, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief, Dog or Cat, 22-65lbs, 225mg, 120ct
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Vetoquinol Zylkene Calming Behavior Support Supplement, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief, Dog or Cat, 22-65lbs, 225mg, 120ct

Pet Size:Medium
Count Per Pack:120

Key item features

  • Help Your Pet Cope With External Stress - Zylkene helps your pet cope with changes in their daily routine, such as travel, celebrations, vet visits, home alone, boarding, loud noises, and more
  • Alpha-Casozephine - A naturally occurring milk protein found in cow's milk that helps promote calming effects in your pet without drowsiness or other side effects found in other calming chews for dogs
  • Lactose-Free and Easy on Sensitive Stomachs - Zylkene's dog calming and cat calming supplements are lactose-free and made with natural ingredients that are easy on sensitive stomachs
  • Veterinarian Recommended Daily Calming Support - Zylkene promotes calming in dogs and cats and can be given daily for behavior support and to help deal with unexpected external stresses
  • Easy to Administer - Open the capsule of Zylkene and add it to your pet's food daily to help them cope with external stresses like separation and improve daily behavior
Current price is $185.99$1.55/count
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Customer ratings & reviews

4.3 out of 5 stars
stars462 ratings418 reviews
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Reviews summary

Pros

  • : Reduces anxiety and stress in pets.
  • : Reduces stress and anxiety during travel.
  • : Helps minimize excessive barking in various situations.
  • : Reduces anxiety and hyperactivity in pets.
  • : Helps reduce anxiety in pets without sedation.

Cons

  • : Struggles in loud environments.
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Showing 1-3 of 418 reviews

Jan 11, 2026
Pamelyn
Item details
Pet size: Extra Small
Count per pack: 30
5 out of 5 stars review

Verified Purchase

Great product for cat's anxiety

I have a 7 pound cat that was experiencing anxiety after I went back to work. She's a beautiful long hair cat who began over-grooming so badly that there were hair chuncks all over the house and she suddenly went from looking like a floofy puff ball to a thin shadow of what she was. The vet recommended those pheromones that you plug into the outlet. They had no effect. Then I found this suppliment. She's been taking it for 2 months now and she's becoming much closer to her previous floof ball self. I talk one capsule, open it up and mix into a small amout of wet food. She loves it as a treat and I'm so happy that her anxiety is so much better. I definitely recommend this product.

Helpful?5CLLJJU39X3O890842396
Dec 15, 2025
Mia
Top Reviewer
Item details
Pet size: Extra Small
Count per pack: 14
5 out of 5 stars review

Verified Purchase

Works great

My dog has PTSD and became addicted to cheese, after researching why %26 how cheese gives the brain dopamine I realized why he was addicted. Unfortunely he is lactose intolerant so I had to cut him off of cheese and put him on a special home cooked diet. I tried every otc suppliment to help him with his anxiety and could not find anything that worked. I saw these and realized they contain the active ingredient in the cheese that was giving my dog the dopamine he needed to feel calm and motivated. I'm am so grateful for the scientist who came to the same conclusion and formulated these capsules because they are a life saver for my dog and for my stress managment. I recommend this to any pet owner who has pets with ADHD sympthoms or anxiety.

Helpful?5CLLJJU39X3O890842396
Apr 14, 2025
Robin
5 out of 5 stars review

Seller Verified Purchase

Calmer Cats, Less Agression

I added a 3rd cat (not kitten) to my home. Despite slow introductions and pheromones running 24/7 throughout the house tensions and agressions were high. At my vets suggestion I began adding Zylkene to their wet food each night. It has made a big difference. Cats are much calmer, they don't love each other, but the agression is minor.

Review from Vetoquinol U.S.A., Inc.
Helpful?5CLLJJU39X3O890842396