THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
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THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules

4.7 stars out of 92 reviews
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92 ratings

Key item features

  • Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
  • Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
  • Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health
  • Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
  • Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Current price is $62.00
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THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
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Comparison Chart:
Vitamin & supplement typeVitamin SupplementsTHORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 CapsulesVitamin SupplementsTHORNE - Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12 - 180 CapsulesVitamin SupplementsTHORNE - Vitamin C 500 mg - Blend of Vitamin C and Citrus Bioflavonoids from Oranges - Supports Immune System* - Third-Party Certified - 90 ServingsVitamin SupplementsSeeking Health B Complex Plus - Vitamin B Complex Supplement with Choline & Riboflavin - Supports Brain Health, Digestion, & Energy - 100 CapsulesVitamin SupplementsTHORNE - Stress B-Complex - Vitamins B2, B6, B12, and Folate in Highly-Absorbable and Active Forms - Extra Vitamin B5 for Adrenal Support, Stress Management and Immune Function* - 60 CapsulesVitamin SupplementsTHORNE - Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep* - Gluten-Free - 180 CapsulesVitamin SupplementsTHORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health, Red Blood Cell Formation* - Gluten & Dairy-Free - 60 CapsulesVitamin SupplementsTHORNE - B-Complex #12 - Vitamin B Complex with Active B12 and Folate - 60 CapsulesVitamin SupplementsTHORNE - B-Complex #6 - Vitamin B Complex with Active Forms of Essential B Vitamins and Extra B6 - 60 CapsulesDietary SupplementsNOW Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
Primary ingredientVitamin B-ComplexTHORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules-THORNE - Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12 - 180 CapsulesVitamin CTHORNE - Vitamin C 500 mg - Blend of Vitamin C and Citrus Bioflavonoids from Oranges - Supports Immune System* - Third-Party Certified - 90 Servings-Seeking Health B Complex Plus - Vitamin B Complex Supplement with Choline & Riboflavin - Supports Brain Health, Digestion, & Energy - 100 CapsulesVitamin B-ComplexTHORNE - Stress B-Complex - Vitamins B2, B6, B12, and Folate in Highly-Absorbable and Active Forms - Extra Vitamin B5 for Adrenal Support, Stress Management and Immune Function* - 60 CapsulesNiacinamideTHORNE - Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep* - Gluten-Free - 180 CapsulesVitamin B ComplexTHORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health, Red Blood Cell Formation* - Gluten & Dairy-Free - 60 CapsulesAquaTHORNE - B-Complex #12 - Vitamin B Complex with Active B12 and Folate - 60 CapsulesVitamin B6THORNE - B-Complex #6 - Vitamin B Complex with Active Forms of Essential B Vitamins and Extra B6 - 60 CapsulesVitamin B12NOW Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
Health concernHeart HealthTHORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 CapsulesBone & Joint HealthTHORNE - Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12 - 180 Capsules-THORNE - Vitamin C 500 mg - Blend of Vitamin C and Citrus Bioflavonoids from Oranges - Supports Immune System* - Third-Party Certified - 90 ServingsEnergy SupportSeeking Health B Complex Plus - Vitamin B Complex Supplement with Choline & Riboflavin - Supports Brain Health, Digestion, & Energy - 100 CapsulesEnergy SupportTHORNE - Stress B-Complex - Vitamins B2, B6, B12, and Folate in Highly-Absorbable and Active Forms - Extra Vitamin B5 for Adrenal Support, Stress Management and Immune Function* - 60 CapsulesSleep SupportTHORNE - Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep* - Gluten-Free - 180 CapsulesEnergy SupportTHORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health, Red Blood Cell Formation* - Gluten & Dairy-Free - 60 CapsulesHair HealthTHORNE - B-Complex #12 - Vitamin B Complex with Active B12 and Folate - 60 CapsulesSupplementationTHORNE - B-Complex #6 - Vitamin B Complex with Active Forms of Essential B Vitamins and Extra B6 - 60 CapsulesEnergy SupportNOW Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
Serv per cont30THORNE - Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules-THORNE - Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12 - 180 Capsules90THORNE - Vitamin C 500 mg - Blend of Vitamin C and Citrus Bioflavonoids from Oranges - Supports Immune System* - Third-Party Certified - 90 Servings-Seeking Health B Complex Plus - Vitamin B Complex Supplement with Choline & Riboflavin - Supports Brain Health, Digestion, & Energy - 100 Capsules60THORNE - Stress B-Complex - Vitamins B2, B6, B12, and Folate in Highly-Absorbable and Active Forms - Extra Vitamin B5 for Adrenal Support, Stress Management and Immune Function* - 60 Capsules180THORNE - Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep* - Gluten-Free - 180 Capsules60THORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health, Red Blood Cell Formation* - Gluten & Dairy-Free - 60 Capsules60THORNE - B-Complex #12 - Vitamin B Complex with Active B12 and Folate - 60 Capsules60THORNE - B-Complex #6 - Vitamin B Complex with Active Forms of Essential B Vitamins and Extra B6 - 60 Capsules-NOW Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
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4.7 out of 5 stars
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Dec 23, 2025
J
Sold byPatternDelivered byWalmart
5 out of 5 stars review

Verified Purchase

Recommend Highly

Seller is Excellent. Product is just what my doctor ordered. Excellent Product %26 Seller. Will BUY AGAIN %26 I Highly recommended THORNE - Methyl-Guard Plus - Active folate (5-MTHF) to others. Tolerate this product well, no taste or fizziness.

Incentivized Review
Helpful?6ZFU6103YF6O148311295
Jun 9, 2025
mary
Sold byPatternDelivered byWalmart
5 out of 5 stars review

Verified Purchase

Because of MTHFR gene differenial, I must take methylated B vitamin complex 2x day per neuro doc. i have tried many brands over many years. in my humble opinion, Thorne digests easiest, thereby providing me w said B vitamins.

Helpful?6ZFU6103YF6O148311295
Jan 29, 2026
Elaine
Sold byPatternDelivered byWalmart
5 out of 5 stars review

Verified Purchase

The recipient of my gift was very happy with the quality

Incentivized Review
Helpful?6ZFU6103YF6O148311295

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