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Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count

4.8 stars out of 11808 reviews
(4.8)|
11.8K ratings
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 CountExcedrin Migraine Caplets for Migraine Headache Relief 100 CountExcedrin Migraine Caplets for Migraine Headache Relief 200 CountExcedrin Migraine Medicine Caplets for Migraine Headache Relief 50 CountExcedrin Migraine Medicine Caplets for Migraine Headache Relief 24 Count
Count Per Pack:100
24, $4.97
20.7 ¢/count
50, $6.87, Out of stock
13.7 ¢/ea
selected, 100, $12.78
12.8 ¢/count
200, $19.73
9.9 ¢/count

Key item features

  • One bottle of 100 Excedrin Migraine Caplets for Migraine Headache Relief
  • Excedrin Migraine works in 3 ways: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance pain relief effect
  • Pain relievers that provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea
  • Excedrin migraine caplets for migraine pain relief combine acetaminophen, aspirin and caffeine
  • Delivers a powerful triple action formula with two pain relievers and an amplifier
  • Migraine relief medicine available in convenient caplet form
  • For some, these Excedrin Migraine caplets relieve migraine pain in 30 minutes
  • HSA and FSA eligible item
Current price is $12.7812.8 ¢/count
Price when purchased online
  • Free 90-day returns
Subscribe, Your usuals, on your schedule, Save time and stay stocked!, $12.78
Your usuals, on your schedule
Save time and stay stocked!
One-time purchase $12.78

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Columbus, 43215
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Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
current price $12.78
Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count
4.8 out of 5 Stars. 11808 reviews
Aleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
Aleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
current price $4.97
Aleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
4.7 out of 5 Stars. 5154 reviews
Comparison Chart:
Over-the-counter medicine typePain ReliefExcedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 CountNaproxen SodiumAleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
Health concernBody Aches & PainsExcedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 CountBody Aches & PainsAleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
Medicine strengthMigraineExcedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 CountNaproxen Sodium 220mgAleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
Dosage2Excedrin Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count-Aleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 24 Count
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Customer ratings & reviews

4.8 out of 5 stars
stars11.8K ratings6,179 reviews
How item rating is calculated
  1. 5 stars86% (10.1K)
  2. 4 stars9% (1,043)
  3. 3 stars2% (279)
  4. 2 stars1% (77)
  5. 1 star2% (222)

Reviews summary

Pros
  • : Fits easily in small bags for on-the-go use.
  • : Relieves migraine symptoms in a short time frame.
  • : Combination of acetaminophen, aspirin, and caffeine.
  • : Designed to fit in small spaces, such as cabinets or purses.
  • : Offers great value at a lower cost.
Neutral
  • : Can be mild, but also bitter or strong.
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Showing 1-3 of 6,179 reviews

Oct 16, 2025
Maggie
Item details
Count per pack: 24
5 out of 5 stars review

Verified Purchase

Fast and effective relief

This is my family's and i's go-to for our headaches. Mine can get pretty bad but it's not a migraine. This takes it away right away. Both my kids and I will take Tylenol ES but it doesn't do the job quite effectively as this does. Just 1 and taken with food and we're all set! Love it and thankful for it <3

Helpful?2E2I9ZJXG9VI10294267
Oct 25, 2025
Monika
Item details
Count per pack: 100
5 out of 5 stars review

Verified Purchase

To me its on the pricier side (100 pills for $13) but this is my go to when i feel a migraine coming on or sometimes when i already have one. If you take it as soon as you feel a migraine coming on it starts to work (at least on me) within 30 minutes. I am a chronic migraine sufferer and i always keep this on hand.

Helpful?2E2I9ZJXG9VI10294267
Sep 9, 2025
Laura
Item details
Count per pack: 100
5 out of 5 stars review

Verified Purchase

does help if you take them right when you feel a migraine coming. but if you suffer with bad migraines like me, it may not work all the time. but it has helped with some and also with them cluster headaches and just down right headaches that want to stay around. just drink plenty of water. always helps with any medicine

Helpful?2E2I9ZJXG9VI10294267

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