Overall pick
Vicks PainQuil Pain Relief Acetaminophen 1000mg Max Strength Adult Pain Reliever Liquid 2x12oz, Backache Headache Relief, 1 Daytime Pain Reliever x 1 Nighttime Pain Relief + Sleep Aid
Key item features
- STARTS WORKING FAST: PainQuil & PainQuil PM Liquid Adult Pain Relievers start working fast for headache relief, backache relief, muscular ache relief, and relief of other minor aches & pains
- MAX STRENGTH PAIN RELIEVERS+: Use PainQuil max strength pain reliever (1000mg Acetaminophen) for pain relief anytime. At night, use PainQuil PM for max strength nighttime pain relief + sleep aid, with 1000mg Acetaminophen and 50mg DPH per dose
- LIQUID PAIN RELIEVER: PainQuil and PainQuil PM Liquids are easy to take and start working fast to relieve aches and pains
- NON-HABIT FORMING: both PainQuil and PainQuil PM are non-habit forming. They are also free of sugar and free of high fructose corn syrup
- FROM THE MAKERS OF VICKS: All PainQuil products are specifically formulated by our team of dedicated scientists, with over 130 years of health care expertise
Specs
- Medicine strength1000; 50MG
- FormLiquid
- SymptomsPain Reliever & Sleep Aid
- Age groupAdult
- Ingredient preferenceGluten-Free
- Treatment effective time4 h
Current price is USD$14.9762.4 ¢/fl oz
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About this item
Product details
FIGHT PAIN FAST with Vicks PainQuil and PainQuil PM adult liquid pain relievers! For pain relief anytime, PainQuil Liquid Pain Reliever starts working fast for max strength headache relief, backache relief, muscular ache relief, and relief of other minor aches & pains. For pain relief at night, PainQuil PM Liquid Pain Reliever starts working fast for headache relief, backache relief, muscular ache relief, and relief of other minor aches & pains + 50mg diphenhydramine HCl per dose to help you sleep soundly. PainQuil and PainQuil PM deliver max strength+ pain relief with 1000mg Acetaminophen per dose. These adult pain reliever liquids are easy to take & deliciously flavored; PainQuil is black cherry flavored, and PainQuil PM is midnight cherry flavored. Both PainQuil and PainQuil PM are non-habit forming. They are also free of high fructose corn syrup and free of sugar. PainQuil and PainQuil PM Liquid Pain Relievers are from the makers of Vicks, with 130 years of health care expertise. +Maximum strength dose of active ingredients per dosing interval, only use as directed.
- STARTS WORKING FAST: PainQuil & PainQuil PM Liquid Adult Pain Relievers start working fast for headache relief, backache relief, muscular ache relief, and relief of other minor aches & pains
- MAX STRENGTH PAIN RELIEVERS+: Use PainQuil max strength pain reliever (1000mg Acetaminophen) for pain relief anytime. At night, use PainQuil PM for max strength nighttime pain relief + sleep aid, with 1000mg Acetaminophen and 50mg DPH per dose
- LIQUID PAIN RELIEVER: PainQuil and PainQuil PM Liquids are easy to take and start working fast to relieve aches and pains
- NON-HABIT FORMING: both PainQuil and PainQuil PM are non-habit forming. They are also free of sugar and free of high fructose corn syrup
- FROM THE MAKERS OF VICKS: All PainQuil products are specifically formulated by our team of dedicated scientists, with over 130 years of health care expertise
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Medicine strength
1000; 50MG
Form
Liquid
Symptoms
Pain Reliever & Sleep Aid
Age group
Adult
Indications
Stop Use Indications
PainQuil PM Pain Reliever + Nighttime Sleep-Aid: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 3 doses (30 mL each) in 24 hours, which is the maximum daily amount for this product, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product. Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening, blisters, rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription), If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; for children under 12 years of age; with any other product containing diphenhydramine, even one used on skin. Ask a doctor before use if you have liver disease, a breathing problem such as emphysema or chronic bronchitis, glaucoma, difficulty in urination due to enlargement of the prostate gland, a sodium-restricted diet. Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin, taking sedatives or tranquilizers. Stop use and ask a doctor if: pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, redness or swelling is present, new symptoms occur, sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. These could be signs of a serious condition. When using this product: avoid alcoholic beverages, drowsiness will occur, do not drive a motor vehicle or operate machinery. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. PainQuil Pain Reliever: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 3 doses (30 mL each) in 24 hours, which is the maximum daily amount for this product, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product. Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening, blisters, rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor before use if you have liver disease, a sodium-restricted diet. Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin. Stop use and ask a doctor if: pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, redness or swelling is present, new symptoms occur. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Body Aches & Pains Sleep Support
Directions
Dosage
Adults & children 12 yrs & over 30 mL at bedtime.
Instructions
PainQuil PM Pain Reliever + Nighttime Sleep-Aid: Take only as directed. Do not exceed 3 doses (30 mL each) per day (24 hours). Only use the dose cup provided. Adults & children 12 yrs & over 30 mL at bedtime. Children under 12 yrs do not use. PainQuil Pain Reliever: Take only as directed. Do not exceed 3 doses (30 mL each) per day (24 hours). Only use the dose cup provided. Adults & children 12 yrs & over 30 mL every 6 hours. Children under 12 yrs ask a doctor.
Warranty
Warranty information
Please be aware that the warranty terms on items offered for sale by third party Marketplace sellers may differ from those displayed in this section (if any). To confirm warranty terms on an item offered for sale by a third party Marketplace seller, please use the 'Contact seller' feature on the third party Marketplace seller's information page and request the item's warranty terms prior to purchase.
Ingredients
Inactive Ingredients
Alcohol, Anhydrous Citric Acid, FD&C Blue No. 1, FD&C Red No. 40, Flavor, Polysorbate 20, Propylene Glycol, Saccharin Sodium, Sodium Benzoate, Sodium Chloride, Sodium Citrate, Sorbitol, Sucralose, Water, Xanthan Gum
Ingredients
Acetaminophen 1000 Mg, Diphenhydramine HCl 50 Mg
Active Ingredients
PainQuil PM Pain Reliever
Active Ingredient Name
In Each 30 mL: Active Ingredients: Acetaminophen (1000 mg), Pain Reliever; Diphenhydramine HCI (50 mg), Nighttime Sleep-Aid. Inactive Ingredients: Alcohol, Anhydrous Citric Acid, FD&C Blue 1, FD&C Red 40, Flavor, Polysorbate 20, Propylene Glycol, Saccharin Sodium, Sodium Benzoate, Sodium Chloride, Sodium Citrate, Sorbitol, Sucralose, Water, Xanthan Gum. In Each 30 mL: Active Ingredients: Acetaminophen (1000 mg), Pain Reliever. Inactive Ingredients: Alcohol, Anhydrous Citric Acid, FD&C Red 40, Flavor, Polysorbate 20, Propylene Glycol, Saccharin Sodium, Sodium Benzoate, Sodium Chloride, Sodium Citrate, Sorbitol, Sucralose, Water, Xanthan Gum. In Each 30 mL: Active Ingredients: Acetaminophen (1000 mg), Pain Reliever; Diphenhydramine HCI (50 mg), Nighttime Sleep-Aid. Inactive Ingredients: Alcohol, Anhydrous Citric Acid, FD&C Blue 1, FD&C Red 40, Flavor, Polysorbate 20, Propylene Glycol, Saccharin Sodium, Sodium Benzoate, Sodium Chloride, Sodium Citrate, Sorbitol, Sucralose, Water, Xanthan Gum. In Each 30 mL: Active Ingredients: Acetaminophen (1000 mg), Pain Reliever. Inactive Ingredients: Alcohol, Anhydrous Citric Acid, FD&C Red 40, Flavor, Polysorbate 20, Propylene Glycol, Saccharin Sodium, Sodium Benzoate, Sodium Chloride, Sodium Citrate, Sorbitol, Sucralose, Water, Xanthan Gum.
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554.6 out of 5 Stars. 55 reviewsSave withShipping, arrives tomorrowBest seller Equate ClearLAX Polyethylene Glycol 3350 Powder for Solution, Unflavored, 7 Doses, Compare to MiraLAX Active Ingredient $4.88
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8 optionsAvailable in additional 8 options$488current price $4.88Options from $4.88 – $56.64Equate ClearLAX Polyethylene Glycol 3350 Powder for Solution, Unflavored, 7 Doses, Compare to MiraLAX Active Ingredient
220444.7 out of 5 Stars. 22044 reviewsSave withPickup todayDelivery todayShipping, arrives in 3+ daysRollback Equate Children's Ibuprofen Oral Suspension, 100 mg, Berry Flavor, Ages 2 to 11 Years, 4 fl oz, Compare to Children's Motrin® Active Ingredient $4.16
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7 optionsAvailable in additional 7 options$416current price $4.16Options from $4.16 – $19.44Equate Children's Ibuprofen Oral Suspension, 100 mg, Berry Flavor, Ages 2 to 11 Years, 4 fl oz, Compare to Children's Motrin® Active Ingredient
43124.8 out of 5 Stars. 4312 reviewsSave withPickup todayDelivery todayShipping, arrives in 3+ daysBest seller Equate Non-Medicated Vapor Inhaler Stick, Menthol Scent, 1 Count, Compare to Vicks® VapoInhaler™ $3.94
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2 optionsAvailable in additional 2 options$394current price $3.94Options from $3.94 – $11.82Equate Non-Medicated Vapor Inhaler Stick, Menthol Scent, 1 Count, Compare to Vicks® VapoInhaler™
29054.7 out of 5 Stars. 2905 reviewsSave withPickup todayDelivery todayShipping, arrives todayBest seller Emergen-C Immune+ Triple Action Immune Support Powder, Betavia (R), 1000Mg Vitamin C, B Vitamins, Vitamin D and Antioxidants, Super Orange, Back to School Essentials – 30 Count $15.98
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2 optionsAvailable in additional 2 optionsSponsored$1598current price $15.98More options from $7.98Emergen-C Immune+ Triple Action Immune Support Powder, Betavia (R), 1000Mg Vitamin C, B Vitamins, Vitamin D and Antioxidants, Super Orange, Back to School Essentials – 30 Count
24524.8 out of 5 Stars. 2452 reviewsSave withPickup todayDelivery todayShipping, arrives in 3+ daysBest seller Nature's Bounty Optimal Solutions Advanced Hair, Skin and Nail Biotin & Vitamins A, C, & E, Women's Multivitamin, Softgels, 120 Ct $9.96 8.3 ¢/count
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Sponsored$996current price $9.968.3 ¢/countNature's Bounty Optimal Solutions Advanced Hair, Skin and Nail Biotin & Vitamins A, C, & E, Women's Multivitamin, Softgels, 120 Ct
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5 optionsAvailable in additional 5 options$198current price $1.98Options from $1.98 – $35.82Equate Upset Stomach Relief Bismuth Liquid, Regular Strength, 8 fl oz, Compare to Pepto-Bismol® Active Ingredient
84164.7 out of 5 Stars. 8416 reviewsSave withPickup todayDelivery todayShipping, arrives today1000+ bought since yesterday Q-tips Cotton Swabs, Original, For Home, First Aid and Beauty, 100% Cotton, 500 Count $3.87
1000+ bought since yesterday
4 optionsAvailable in additional 4 options$387current price $3.87Options from $3.87 – $11.61Q-tips Cotton Swabs, Original, For Home, First Aid and Beauty, 100% Cotton, 500 Count
369444.8 out of 5 Stars. 36944 reviewsSave withPickup todayDelivery todayBest seller Nature's Bounty Hair Skin and Nail Vitamins With Biotin, Women's Multivitamin, Strawberry Gummies, 90 Ct $7.88
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2 optionsAvailable in additional 2 options$788current price $7.88Options from $7.88 – $15.76Nature's Bounty Hair Skin and Nail Vitamins With Biotin, Women's Multivitamin, Strawberry Gummies, 90 Ct
284814.2 out of 5 Stars. 28481 reviewsSave withPickup todayDelivery todayShipping, arrives in 3+ days1000+ bought since yesterday Hanhoo Blemish Patch with Hydrocolloid, for All Skin Types, Acne Treatment, 36 Ct. $2.56
1000+ bought since yesterday
3 optionsAvailable in additional 3 options$256current price $2.56Options from $2.56 – $7.68Hanhoo Blemish Patch with Hydrocolloid, for All Skin Types, Acne Treatment, 36 Ct.
34894.4 out of 5 Stars. 3489 reviewsSave withPickup todayDelivery today1000+ bought since yesterday Children's Motrin Ibuprofen Kids Medicine, Berry Flavored, 8 fl. oz $11.97
1000+ bought since yesterday
2 optionsAvailable in additional 2 options$1197current price $11.97More options from $7.68Children's Motrin Ibuprofen Kids Medicine, Berry Flavored, 8 fl. oz
37884.8 out of 5 Stars. 3788 reviewsSave withPickup todayDelivery todayShipping, arrives todayIn 50+ people's carts Neutrogena Fragrance Free Makeup Remover Wipes, Face Cleansing Towelettes, 25 Count, 2 Pack $5.67
In 50+ people's carts
2 optionsAvailable in additional 2 options$567current price $5.67Options from $5.67 – $9.97Neutrogena Fragrance Free Makeup Remover Wipes, Face Cleansing Towelettes, 25 Count, 2 Pack
240854.6 out of 5 Stars. 24085 reviewsSave withPickup todayDelivery todayShipping, arrives today
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Showing 1-3 of 153 reviews
Sep 29, 2025
anyi722
5 out of 5 stars review
Verified Purchase
Excellent product!
Helped my 13 year old Grandson so much after his Orthodontia appointment to tighten his braces! Thank you for rapid service to alleviate his pain and make his appetite return %26 his pain decrease! His smile return within a day instead of a week or two! Thank you again! ;)))
Helpful?5B2PKFA1PY355322135456
Nov 4, 2025
Deborah
Top Reviewer
5 out of 5 stars review
Verified Purchase
The PM does s great job. I have pain in various places but the back is the worst. Sciatica nerve is horrible but this calms it and I get to sleep quickly. I've been using Equate for Arthritis 650 mg and it does a great job but with the added sleep med this is definitely my new Pm treatment.
Helpful?5B2PKFA1PY355322135456
Jan 31, 2026
stephanie
5 out of 5 stars review
Verified Purchase
great product
yes would recommend......felt like my arms were going to break off these past two weeks....this showed up after the snow storm. took some of it...20 minutes later felt relief. came here to order more for the future and decided to write this. felt like the pain went from a 9 to a 5/6. very happy with the result. wheelchair user.
Helpful?5B2PKFA1PY355322135456
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