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100+ bought since yesterdayPopular pick
Alka-Seltzer Plus Maximum Strength Cold & Flu Medicine, Day + Night, Liquid Gels, 20 Count
Key item features
- Provides temporary daytime relief from nasal congestion, cough, headache & body ache, sore throat, sinus pressure, and fever
- Provides temporary nighttime relief from runny nose, nasal congestion, cough, headache & body ache, sore throat, and fever
- Daytime and nighttime medication in one convenient package
- Package contains 20 liquid gels, 1 dose (2 liquid gels)
- Use as directed
Specs
- Health concernCold
- Over-the-counter medicine typeCough & Cold
- FormGel
- Age groupAdult, Teen, Senior, Tween
Reviews summary
Pros
- : Relieves nasal congestion and sinus issues.
- : Provides quick symptom relief within a short period.
- : Provides fast and long-lasting relief from symptoms.
- : Arrives at moments that meet user needs.
- : Contain liquid-gel fillings and have a compact size.
Neutral
- : Can be convenient with dual-formula packs, but relief duration varies.
Generated by AI
Current price is USD$7.4737.4 ¢/count
Price when purchased online
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FSA and HSA eligible
About this item
Product details
When you need daytime relief from your cold or flu symptoms – and a restful night so you can tackle the next day – turn to Alka-Seltzer Plus Maximum Strength* Day & Night Cold & Flu Liquid Gels for fast, effective relief. In one convenient package you get: Daytime cold and flu symptom relief from: Nasal Congestion, Cough, Headache & Body Ache, Sore Throat, Sinus Pressure & Fever and Nighttime cold and flu medicine for relief from: Runny Nose, Nasal Congestion, Cough, Headache & Body Ache, Sore Throat & Fever. *Based on 4 hour dosing.
- Provides temporary daytime relief from nasal congestion, cough, headache & body ache, sore throat, sinus pressure, and fever
- Provides temporary nighttime relief from runny nose, nasal congestion, cough, headache & body ache, sore throat, and fever
- Daytime and nighttime medication in one convenient package
- Package contains 20 liquid gels, 1 dose (2 liquid gels)
- Use as directed
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Health concern
Cold
Over-the-counter medicine type
Cough & Cold
Form
Gel
Age group
Adult, Teen, Senior, Tween
Indications
Stop Use Indications
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, or 3 or more alcoholic drinks every day while using this product.Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening, blisters, rash, hives, facial swelling, asthma (wheezing), or shock. If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Do not use if you have ever had an allergic reaction to this product or any of its ingredients. Do not use in children under 12 years of age.Ask a doctor before use if you have: liver disease, heart disease, high blood pressure, thyroid disease, diabetes, cough with excessive phlegm (mucus), difficulty in urination due to enlargement of the prostate gland, or persistent or chronic cough such as occurs with smoking, asthma, or emphysema.Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin.When using this product do not exceed the recommended dosage.Stop use and ask a doctor if pain, cough, or nasal congestion gets worse or lasts more than 7 days. Stop use and ask a doctor if your fever gets worse or lasts more than 3 days, redness or swelling is present, new symptoms occur, or your cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occurs.If you are pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of an overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Cold
Directions
Dosage
Do not take more than the recommended dose. Do not exceed 10 capsules in 24 hours or as directed by a doctor.
Instructions
DAY: Adults and children 12 years and over: Take 2 capsules with water every 4 hours. Children under 12 years: Do not use NIGHT: Adults and children 12 years and over: Take 2 capsules with water every 4 hours. Children under 12 years: Do not use
Warranty
Warranty information
Questions or comments? Please call 1-800-986-0369 (Mon-Fri 8am-8pm ET)
Warranty url
Ingredients
Inactive Ingredients
DAY: FD&C red #40, FD&C yellow #6, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide NIGHT:FD&C blue #1, D&C yellow #10, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide
Ingredients
DAY: Acetaminophen 325 mg Dextromethorphan hydrobromide 10 mg Phenylephrine hydrochloride 5 mg NIGHT: Acetaminophen 325 mg Dextromethorphan hydrobromide 10 mg Doxylamine succinate 6.25 mg Phenylephrine hydrochloride 5 mg
Active Ingredients
Alka-Seltzer Plus® Night Cold & Flu Formula Liquid Gels: Acetaminophen 325 mg, Dextromethorphan Hydrobromide 10 mg, Doxylamine Succinate 6.25 mg, Phenylephrine Hydrochloride 5 mg
Active Ingredient Name
Alka-Seltzer Plus® Night Cold & Flu Formula Liquid Gels: Acetaminophen 325 mg, Dextromethorphan Hydrobromide 10 mg, Doxylamine Succinate 6.25 mg, Phenylephrine Hydrochloride 5 mg
Warnings
Warning Text
Alka-Setler Plus® Day Non-Drowsy Cold & Flu Formula Liquid Gels. WARNINGS. LIVER WARNING: This product contains acetaminophen. Severe liver damage may occur if you take. ? more than 10 capsules in 24 hours, which is the maximum daily amount for this product. ? with other drugs containing acetaminophen. ? 3 or more alcoholic drinks every day while using this product. ALLERGY ALERT: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:. ? skin reddening. ? blister. ? rash. ? hives. ? facial swelling. ? asthma (wheezing). ? shock. If a skin or general allergic reaction occurs, stop use and seek medical help right away. SORE THROAT WARNING: If sore throat is severe, persists for more than 2 days, is accompanied, or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Alka-Setler Plus® Night Cold & Flu Formula Liquid Gels. WARNINGS. LIVER WARNING: This product contains acetaminophen. Severe liver damage may occur if you take. ? more than 10 capsules in 24 hours, which is the maximum daily amount for this product. ? with other drugs containing acetaminophen. ? 3 or more alcoholic drinks every day while using this product. ALLERGY ALERT: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:. ? skin reddening. ? blister. ? rash. ? hives. ? facial swelling. ? asthma (wheezing). ? shock. If a skin or general allergic reaction occurs, stop use and seek medical help right away. SORE THROAT WARNING: If sore throat is severe, persists for more than 2 days, is accompanied, or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. DO NOT USE TO SEDATE CHILDREN. DO NOT USE. ? with vary other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. DO NOT TAKE THESE PRODUCTS AT THE SAME TIME. DO NOT USE IF BLISTER IS CUT OR BROKEN,. DOES NOT CONTAIN ASPIRIN
State Chemical Disclosure
n/a
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Customer ratings & reviews
How item rating is calculated
Reviews summary
Pros
- : Relieves nasal congestion and sinus issues.
- : Provides quick symptom relief within a short period.
- : Provides fast and long-lasting relief from symptoms.
- : Arrives at moments that meet user needs.
- : Contain liquid-gel fillings and have a compact size.
Neutral
- : Can be convenient with dual-formula packs, but relief duration varies.
Generated by AI
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Showing 1-3 of 726 reviews
Dec 30, 2025
c
Top Reviewer
Item details
Count: 20
5 out of 5 stars review
Verified Purchase
Good product, good results
This is tried and true. I have used Alka Seltzer cold for years. Every time I try some new cold and flu relief, I always end up buying Alka Seltzer again. Ye!=son the market but for me, the best results
Helpful?e32a62e0-d40b-11f0-ac61-41720b250fb934718113
Apr 27, 2025
Paula
Top Reviewer
Item details
Count: 20
5 out of 5 stars review
Verified Purchase
Only Cold Medicine I buy
A friend introduced me to this cold medicine years ago. It is the only one I use now. I know recent reports came out about combo cold medicine but what i like about this one is that decongestant that is in it. If you have the nose drips then this will help to dry you out. You can tell it's time for the next dose when your nose starts running again. I used to use Dayquil but it never dried me out. It's great especially if you don't' want to use the stuff they keep behind the counter. That stuff makes me too jumpy so this dries me out without jumping at every loud noise!
Helpful?e32a62e0-d40b-11f0-ac61-41720b250fb934718113
Nov 13, 2025
Terri
Item details
Count: 20
5 out of 5 stars review
Verified Purchase
Soothing to my throat
I have a scratchy, achy throat because of nose drainage and head congestion. The cough drops really soothe my symtoms and has a great taste
Helpful?e32a62e0-d40b-11f0-ac61-41720b250fb934718113
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5254.7 out of 5 Stars. 525 reviewsSave withPickup tomorrowDelivery todayShipping, arrives in 2 daysAlka-Seltzer Plus Powermax Sinus & Cold Medicine, Liquid Gels, 24 Count $9.47
2 optionsAvailable in additional 2 options$947current price $9.47Alka-Seltzer Plus Powermax Sinus & Cold Medicine, Liquid Gels, 24 Count
3944.6 out of 5 Stars. 394 reviewsSave withPickup tomorrowDelivery todayShipping, arrives in 2 daysBest seller Advil Multi-Symptom Cold and Flu Medicine Fever Reducer Coated Tablets, 20 Count $9.48
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2 optionsAvailable in additional 2 options$948current price $9.48Options from $9.48 – $28.44Advil Multi-Symptom Cold and Flu Medicine Fever Reducer Coated Tablets, 20 Count
52034.7 out of 5 Stars. 5203 reviewsSave withPickup tomorrowDelivery todayShipping, arrives in 2 daysAlka-Seltzer Plus Cold Formula Sparkling Original Effervescent Tablets, 36 Ct $21.46 59.6 ¢/ea
$2146current price $21.4659.6 ¢/eaAlka-Seltzer Plus Cold Formula Sparkling Original Effervescent Tablets, 36 Ct
2804.6 out of 5 Stars. 280 reviewsShipping, arrives in 3+ daysMucinex Fast-Max Adult Nighttime Cold and Flu Liquid, 6 fl oz $22.13 $3.69/fl oz
$2213current price $22.13$3.69/fl ozMucinex Fast-Max Adult Nighttime Cold and Flu Liquid, 6 fl oz
244.7 out of 5 Stars. 24 reviewsShipping, arrives in 3+ daysTheraflu Max Strength Cough Cold and Flu Daytime Relief Medicine Powder, Honey Lemon Flavored, 6 Count $7.98 $1.33/count
$798current price $7.98$1.33/countTheraflu Max Strength Cough Cold and Flu Daytime Relief Medicine Powder, Honey Lemon Flavored, 6 Count
40074.6 out of 5 Stars. 4007 reviewsSave withTheraflu Max Strength Cough Cold and Flu Day and Nighttime Relief Medicine Powder With Acetaminophen, 12 Count $13.48 $1.12/count
$1348current price $13.48$1.12/countTheraflu Max Strength Cough Cold and Flu Day and Nighttime Relief Medicine Powder With Acetaminophen, 12 Count
12174.8 out of 5 Stars. 1217 reviewsSave withMucinex Fast-Max Cold & Flu & Nightshift Severe Cold & Flu Medicine, OTC Cough Relief, 2x6 fl oz $22.44 $1.87/fl oz
$2244current price $22.44$1.87/fl ozMucinex Fast-Max Cold & Flu & Nightshift Severe Cold & Flu Medicine, OTC Cough Relief, 2x6 fl oz
6974.7 out of 5 Stars. 697 reviewsSave withPickup tomorrowDelivery todayShipping, arrives in 2 days