500+ bought since yesterdayRollbackOverall pick
Equate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients
Key item features
- Active Ingredients: Compare to the active ingredients of Vicks NyQuil Cold and Flu, Acetaminophen 650 mg, Dextromethorphan HBr 30 mg and Doxylamine Succinate 12.5 mg
- Nighttime Relief: This liquid medicine provides powerful nighttime relief so you can rest
- Effective: Each dose contains a pain reliever, fever reducer, cough suppressant, antihistamine and ten percent alcohol to calm your cold and flu symptoms to help you sleep
- Powerful Liquid: This cherry flavored liquid medicine provides powerful, multi-symptom relief; for adults and children 12 and over; gluten free
- Maximum Strength: Equate Nighttime Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, sneezing, runny nose and cough
Specs
- Over-the-counter medicine typePain Relief, Fever Reducer, Cough & Cold, Flu Relief, Acetaminophen, Antihistamines
- Health concernCold, Flu, Body Aches & Pains
- BrandEquate
- Age groupAdult
- FormLiquid
- FlavorCherry
Reviews summary
Pros
- : Offers significant savings compared to competitors.
Neutral
- : Can be rich, but also watery.
Generated by AI
Current price is USDNow $9.97
You save $3.01
was $12.98$12.98
41.5 ¢/fl ozYou save$3.01
Price when purchased online
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About this item
Product details
Equate Nighttime Cold and Flu Relief is a powerful liquid medicine that provides maximum strength relief for common cold and flu-like symptoms so you can rest. Each dose combines Acetaminophen 650 mg (Pain Reliever/Fever Reducer), Dextromethorphan HBr 30 mg (Cough Suppressant) and Doxylamine Succinate 12.5 mg (Antihistamine) with ten percent alcohol to calm your nighttime cold and flu symptoms to help you sleep. This cherry flavored liquid medicine provides maximum strength relief of minor aches and pains, fever, sore throat, cough, runny nose and sneezing. For adults and children 12 years and over, this gluten-free medicine comes with a dosage cup. Compare to Vicks NyQuil active ingredients. Get the rest you need with Equate Nighttime Cold and Flu Relief.
Making the right health decisions can be challenging. With a complete range of products and simple solutions, Equate allows you to take care of your family with confidence.
- Active Ingredients: Compare to the active ingredients of Vicks NyQuil Cold and Flu, Acetaminophen 650 mg, Dextromethorphan HBr 30 mg and Doxylamine Succinate 12.5 mg
- Nighttime Relief: This liquid medicine provides powerful nighttime relief so you can rest
- Effective: Each dose contains a pain reliever, fever reducer, cough suppressant, antihistamine and ten percent alcohol to calm your cold and flu symptoms to help you sleep
- Powerful Liquid: This cherry flavored liquid medicine provides powerful, multi-symptom relief; for adults and children 12 and over; gluten free
- Maximum Strength: Equate Nighttime Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, sneezing, runny nose and cough
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Over-the-counter medicine type
Pain Relief, Fever Reducer, Cough & Cold, Flu Relief, Acetaminophen, Antihistamines
Health concern
Cold, Flu, Body Aches & Pains
Active ingredients
Acetaminophen 650mg, Dextromethorphan HBr 30mg, Doxylamine succinate 12.5mg
Medicine strength
Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, Doxylamine succinate 12.5 mg
Indications
Stop Use Indications
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; glaucoma; cough that occurs with too much phlegm (mucus); a breathing problem such as emphysema or chronic bronchitis; trouble urinating due to an enlarged prostate gland; persistent or chronic cough as occurs with smoking, asthma, or emphysema; a sodium-restricted diet. Ask a doctor or pharmacist before use if you are: taking sedatives or tranquilizers; taking the blood thinning drug warfarin. When using this product: excitability may occur, especially in children; marked drowsiness may occur; avoid alcoholic drinks; be careful when driving a motor vehicle or operating machinery; alcohol, sedatives, and tranquilizers may increase drowsiness. Stop use and ask a doctor if: pain or cough gets worse or lasts more than 7 days; fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Cold Flu Body Aches & Pains
Directions
Dosage
Do not take more than directed (see Overdose warning). Do not take more than 4 doses in any 24-hour period. Measure only with dosing cup provided. Do not use any other dosing device. mL = milliliter. Keep dosing cup with product. Adults and children 12 years and over: 30 mL every 6 hours. Children under 12 years of age: do not use. When using other Daytime or Nighttime products, carefully read each label to ensure correct dosing.
Instructions
Do not take more than directed (see Overdose warning). Do not take more than 4 doses in any 24-hour period. Measure only with dosing cup provided. Do not use any other dosing device. mL = milliliter. Keep dosing cup with product. Adults and children 12 years and over: 30 mL every 6 hours. Children under 12 years of age: do not use. When using other Daytime or Nighttime products, carefully read each label to ensure correct dosing.
Ingredients
Inactive Ingredients
Inactive ingredients: acesulfame potassium, alcohol, citric acid, FD&C blue #1, FD&C red #40, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate
Ingredients
Active Ingredients: Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, Doxylamine succinate 12.5 mg. Inactive ingredients: acesulfame potassium, alcohol, citric acid, FD&C blue #1, FD&C red #40, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate
Active Ingredients
Acetaminophen 650mg Dextromethorphan HBr 30mg Doxylamine succinate 12.5mg
Compare with similar items
| Product | Viewing this itemEquate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients  Now $9.97 current price Now $9.97, Was $12.98$12.98 19164.7 out of 5 Stars. 1916 reviews | Equate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients  Now $9.97 current price Now $9.97, Was $12.98$12.98 18774.7 out of 5 Stars. 1877 reviews | Equate Daytime Cold and Flu Relief, Non-Drowsy, Multi-Symptom Medicine for Cough, 12 fl oz  Now $5.47 current price Now $5.47, Was $6.98$6.98 16424.7 out of 5 Stars. 1642 reviews |
|---|
| Over-the-counter medicine type | Pain ReliefEquate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | Pain ReliefEquate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | Cough & ColdEquate Daytime Cold and Flu Relief, Non-Drowsy, Multi-Symptom Medicine for Cough, 12 fl oz |
|---|---|---|---|
| Health concern | ColdEquate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | ColdEquate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | ColdEquate Daytime Cold and Flu Relief, Non-Drowsy, Multi-Symptom Medicine for Cough, 12 fl oz |
| Age group | AdultEquate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | AdultEquate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | AdultEquate Daytime Cold and Flu Relief, Non-Drowsy, Multi-Symptom Medicine for Cough, 12 fl oz |
| Form | LiquidEquate Nighttime Cold and Flu Relief Liquid, Cherry Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | LiquidEquate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients | LiquidEquate Daytime Cold and Flu Relief, Non-Drowsy, Multi-Symptom Medicine for Cough, 12 fl oz |
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4154.8 out of 5 Stars. 415 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Max Strength Non-Drowsy Daytime Severe Cold Flu Softgels, 325mg, 24 Count $7.98 33.3 ¢/count
$798current price $7.9833.3 ¢/countEquate Max Strength Non-Drowsy Daytime Severe Cold Flu Softgels, 325mg, 24 Count
3864.6 out of 5 Stars. 386 reviewsSave withShipping, arrives in 3+ daysRollback Equate Maximum Strength 12 Hour Mucus Relief DM Guaifenesin and Dextromethorphan Extended Release Tablets, 1200 mg/60 mg, 14 Count, Compare to Maximum Strength Mucinex® DM Active Ingredients $6.37 Was $8.92 45.5 ¢/count
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Now$637current price Now $6.37, Was $8.92$8.9245.5 ¢/countEquate Maximum Strength 12 Hour Mucus Relief DM Guaifenesin and Dextromethorphan Extended Release Tablets, 1200 mg/60 mg, 14 Count, Compare to Maximum Strength Mucinex® DM Active Ingredients
18494.6 out of 5 Stars. 1849 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Children's Diphenhydramine Allergy Relief Oral Solution, 12.5 mg, Cherry Flavor, Ages 6 to 11 Years, 8 fl oz, Compare to Children's Benadryl® Allergy Active Ingredient $6.23
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4644.8 out of 5 Stars. 464 reviewsSave withPickup todayDelivery todayShipping, arrives todayEquate Effervescent Cold Relief, 48 Tablets, Compare to Alka-Seltzer Plus® Cold Active Ingredients $5.54
2 optionsAvailable in additional 2 options$554current price $5.54Equate Effervescent Cold Relief, 48 Tablets, Compare to Alka-Seltzer Plus® Cold Active Ingredients
26014.8 out of 5 Stars. 2601 reviewsSave withPickup todayDelivery todayShipping, arrives todayVicks DayQuil Severe Cold and Flu Liquid, Cold and Flu Medicine for Adults, Honey, 12 Fl oz $11.97
3 optionsAvailable in additional 3 options$1197current price $11.97Vicks DayQuil Severe Cold and Flu Liquid, Cold and Flu Medicine for Adults, Honey, 12 Fl oz
12484.6 out of 5 Stars. 1248 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowBest seller Equate Extra Strength Heartburn Relief + Gas Relief Chews, Mixed Berry, 54 Chewable Tablets $5.58
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33534.7 out of 5 Stars. 3353 reviewsSave withPickup todayDelivery todayShipping, arrives todayEquate Ultra Strength Upset Stomach Relief Bismuth Liquid, 12 fl oz, Compare to Pepto-Bismol® Ultra Active Ingredient $4.38
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12614.7 out of 5 Stars. 1261 reviewsSave withPickup todayDelivery todayShipping, arrives today
Customer ratings & reviews
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Reviews summary
Pros
- : Offers significant savings compared to competitors.
Neutral
- : Can be rich, but also watery.
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Showing 1-3 of 214 reviews
Dec 11, 2025
Pam
Top Reviewer
5 out of 5 stars review
Verified Purchase
Nyquil has met its match.
Taking Equate Nighttime Cold and Flu Relief has given me quick relief, making it so much easier to get a good night's sleep. And a capful of the cherry flavor is tasty. The Equate brand is so much cheaper and just as good, if not better than the Brand name products.
Helpful?7FHQY07CIBA81892882346
Jan 3, 2026
Terri
5 out of 5 stars review
Verified Purchase
This is a very good value and it works.. taste nice and takes effect in about 20 minutes 💤 I'm even able to breathe better with my CPAP.. maybe because I'm more relaxed... it's something I use when I just can't fall sleep because it helps me turn off my brain from thinking about stuff... so I can rest well..I do recommend it to my friends and family..it works as good as the name brand and less money
Helpful?7FHQY07CIBA81892882346
Dec 18, 2025
Franz
Top Reviewer
5 out of 5 stars review
Verified Purchase
Works well for flu and cold and a better night
Works well for flu relief and a better, quieter night's sleep. Like any cold or flu medication, it will help ease your symptoms, but if they persist, see a doctor.
Helpful?7FHQY07CIBA81892882346
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