Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
Hero image 0 of Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps, 0 of 12
500+ bought since yesterday, try a subscriptionOverall pick
Equate

Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps

4.8 stars out of 1188 reviews
(4.8)|
1,188 ratings

Key item features

  • Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg and Diphenhydramine HCL 25 mg, 80 Gelcaps
  • Extra strength pain reliever/nighttime sleep-aid
  • Non-habit forming
  • Suitable for adults and children 12 years and over
  • Active ingredient (in each caplet): Diphenhydramine Hydrochloride 25 mg (nighttime sleep-aid), Acetaminophen 500 mg (pain reliever)
  • Compare to Extra Strength Tylenol PM active ingredients
Current price is $5.677.1 ¢/count
Price when purchased online
  • Free 90-day returns
Subscribe, Your usuals, on your schedule, Save time and stay stocked!, $5.67
Your usuals, on your schedule
Save time and stay stocked!
One-time purchase $5.67

How do you want your item?

Try 30 days of Free Shipping with Walmart+! Choose plan at checkout.
How do you want your item?
Columbus, 43215
Arrives by Today
.
Order within 4 hr 47 min
Sold and shipped by Walmart.com
Free 90-day returns
This item is gift eligible
walmart plus

Get free delivery, shipping and more*

*Restrictions apply
Try Walmart+ now

About this item

Product details

Specifications

Indications

Directions

Ingredients

Warnings

Compare with similar items

Comparison Overview:
Product

Viewing this item

Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
current price $5.67
Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
4.8 out of 5 Stars. 1188 reviews
Equate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
Equate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
current price $9.94
Equate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
4.8 out of 5 Stars. 6472 reviews
Comparison Chart:
Over-the-counter medicine typePain ReliefEquate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 GelcapsHeadache ReliefEquate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
Health concernMuscle ReliefEquate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 GelcapsArthritisEquate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
Active ingredientsAcetaminophenEquate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 GelcapsAcetaminophenEquate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
Medicine strength500mg; 25mgEquate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps500mgEquate Extra Strength Pain Reliever Acetaminophen Gel Caps, 500mg, Pain Reliever/Fever Reducer, Easy Open Cap, 225 Count, Compare to Tylenol® Extra Strength Rapid Release Gels Active Ingredient
Now hiding additional rows in the Table

Customer ratings & reviews

4.8 out of 5 stars
stars1,188 ratings102 reviews
How item rating is calculated
  1. 5 stars87% (1,030)
  2. 4 stars8% (93)
  3. 3 stars3% (35)
  4. 2 stars1% (11)
  5. 1 star2% (19)

Reviews summary

Pros
  • : Relieves discomfort during rest and sleep.
  • : Helps users fall asleep quickly.
  • : Offers similar quality at a lower price.
Generated by AI

Customer images

Filtered and sorted results would be available on the new 'Customer ratings & reviews' page.
Sort by |

Showing 1-3 of 102 reviews

Jun 3, 2025
SARAH
Top Reviewer
5 out of 5 stars review

Verified Purchase

ENABLES ME TO SLEEP NO BACK PAIN NON HABIT FORMING

I'VE BEEN USING THESE FOR YEARS... THEY WORK MUCH BETTER THAN THE "NAME BRANDS" AT "HUGE SAVINGS." "THEY'VE NOT BEEN HABIT FORMING, SO THAT'S ALWAYS GOOD. THEY WORK TO HELP ME SLEEP AND RELIEVE MY BACK PAIN THAT I'VE SUFFERED WITH FOR DECADES. I HIGHLY RECOMMEND. smh

Helpful?7CMSW0A53FMW10534002807
Feb 6, 2026
Dif
Top Reviewer
5 out of 5 stars review

Verified Purchase

When my arthritis is acting up late in the day, the only thing that helps is Equate extra pain relief PM Acetaminophen. I have been using it for many years to relieve my pain. I have been given prescriptions after prescription that never worked for me until I tried this. One of the best things it helps me to sleep. I wouldn't say this if it wasn't true. I hope it helps you to.

Helpful?7CMSW0A53FMW10534002807
Oct 11, 2025
Walmart customer
Top Reviewer
5 out of 5 stars review

Verified Purchase

I bought these as I have before. Acetaminophen works for my aches and pains. I will continue to use it. With all the misinformation that is out there, people should make their own decisions about what is factual and what is not.

Helpful?7CMSW0A53FMW10534002807

Frequently bought together

Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps $5.67 7.1 ¢/count

Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps
current price $5.67
7.1 ¢/count

Equate Extra Strength Pain Reliever PM, Acetaminophen 500 mg & Diphenhydramine HCL 25 mg, 80 Gelcaps

4.8 out of 5 Stars. 1188 reviews

Best seller Equate Immune Support Dietary Supplement Effervescent Tablets, Orange Flavor, 10 Count, Compare to Airborne® Immunity Support Dietary Ingredients $5.47 54.7 ¢/count

Best seller
Equate Immune Support Dietary Supplement Effervescent Tablets, Orange Flavor, 10 Count, Compare to Airborne® Immunity Support Dietary Ingredients
current price $5.47
54.7 ¢/count

Equate Immune Support Dietary Supplement Effervescent Tablets, Orange Flavor, 10 Count, Compare to Airborne® Immunity Support Dietary Ingredients

4.8 out of 5 Stars. 351 reviews

Best seller Equate Extra Strength Cool & Heat Medicated Patch 5% Menthol, 5 Count, Compare to Extra Strength Icy Hot® Back Patch $4.66 93.2 ¢/count

Best seller
Equate Extra Strength Cool & Heat Medicated Patch 5% Menthol, 5 Count, Compare to Extra Strength Icy Hot® Back Patch
current price $4.66
93.2 ¢/count

Equate Extra Strength Cool & Heat Medicated Patch 5% Menthol, 5 Count, Compare to Extra Strength Icy Hot® Back Patch

4.4 out of 5 Stars. 1551 reviews

Equate Makeup Remover Cleansing Towelette Wipes for Face Care, Fragrance Free & Alcohol Free, 40 Count, Compare to Neutrogena® Makeup Remover Cleansing Towelettes Fragrance Free $3.74 9.4 ¢/count

Equate Makeup Remover Cleansing Towelette Wipes for Face Care, Fragrance Free & Alcohol Free, 40 Count, Compare to Neutrogena® Makeup Remover Cleansing Towelettes Fragrance Free
current price $3.74
9.4 ¢/count

Equate Makeup Remover Cleansing Towelette Wipes for Face Care, Fragrance Free & Alcohol Free, 40 Count, Compare to Neutrogena® Makeup Remover Cleansing Towelettes Fragrance Free

4.3 out of 5 Stars. 611 reviews
Current price is $19.54
Items may be delivered on different dates