Hero image 0 of Equate Max Strength Severe Cold & Flu Relief Daytime and Nighttime Combo Pack, 12 fl oz, 0 of 7
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Equate Max Strength Severe Cold & Flu Relief Daytime and Nighttime Combo Pack, 12 fl oz
Key item features
- Compare this daytime and nighttime cold medicine to Vicks® DayQuil® Severe and Vicks NyQuil® Severe active ingredients
- Temporarily relieves nasal and sinus congestion and sinus pressure
- Soothes cough from minor throat and bronchial irritation
- Daytime contains Acetaminophen, Dextromethorphan HBr, Guaifenesin, and Phenylephrine HCl for effective relief
- Nighttime contains Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, and Phenylephrine HCl to help you rest
- Alcohol-free, gluten-free; day formula thins mucus, night formula reduces sneezing and runny nose for better sleep
Specs
- Health concernCold
- SymptomsCough, Cold, Flu
- Ingredient preferenceAlcohol-Free
- Medicine strength650 mg / 325 mg
- Age groupAdult
- FormLiquid
Reviews summary
Pros
- : Offers great value for the product's functionality.
Neutral
- : Can be rich and smooth, but also bitter or unpleasant for some.
Generated by AI
Current price is USDNow $11.67
You save $3.31
was $14.98$14.98
48.6 ¢/fl ozYou save$3.31
Price when purchased online
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FSA and HSA eligible
About this item
Product details
Get multi-symptom relief with Equate Max Strength Severe Cold & Flu Relief combo. Compare to Vicks® DayQuil®and NyQuil®* Severe active ingredients. The Daytime formula relieves nasal and sinus congestion, cough, headache, fever, sore throat, and chest congestion while thinning mucus for easier coughing. The Nighttime formula soothes aches, sneezing, runny nose, and helps you get the rest you need. Both are alcohol-free and gluten-free, relieving sinus pressure, minor pain, and cough from throat and bronchial irritation. Daytime is antihistamine free; Nighttime is sugar-free and mixed berry flavored. This combo pack offers trusted relief to keep you comfortable day and night with same active ingredients as the leading brands,at a lower price. * Vicks® NyQuil® and DayQuil® are registered trademarks of The Procter & Gamble Company
- Compare this daytime and nighttime cold medicine to Vicks® DayQuil® Severe and Vicks NyQuil® Severe active ingredients
- Temporarily relieves nasal and sinus congestion and sinus pressure
- Soothes cough from minor throat and bronchial irritation
- Daytime contains Acetaminophen, Dextromethorphan HBr, Guaifenesin, and Phenylephrine HCl for effective relief
- Nighttime contains Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, and Phenylephrine HCl to help you rest
- Alcohol-free, gluten-free; day formula thins mucus, night formula reduces sneezing and runny nose for better sleep
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Health concern
Cold
Symptoms
Cough, Cold, Flu
Ingredient preference
Alcohol-Free
Medicine strength
650 mg / 325 mg
Indications
Stop Use Indications
Nighttime Severe Cold & Flu: Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; heart disease; high blood pressure; thyroid disease; diabetes; glaucoma; cough that occurs with too much phlegm (mucus); a breathing problem such as emphysema or chronic bronchitis; trouble urinating due to an enlarged prostate gland; persistent or chronic cough such as occurs with smoking, asthma, or emphysema; a sodium-restricted diet. Ask a doctor or pharmacist before use if you are: taking sedatives or tranquilizers; taking the blood thinning drug warfarin. When using this product: do not use more than directed; excitability may occur, especially in children; marked drowsiness may occur; avoid alcoholic drinks; be careful when driving a motor vehicle or operating machinery; alcohol, sedatives, and tranquilizers may increase drowsiness. Stop use and ask a doctor if: you get nervous, dizzy or sleepless; pain, nasal congestion, or cough gets worse or lasts more than 7 days; fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. Daytime Severe Cold & Flu: Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if: adult takes more than 4,000 mg of acetaminophen in 24 hours; child takes more than 5 doses in 24 hours; taken with other drugs containing acetaminophen; adult has 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; heart disease; thyroid disease; diabetes; high blood pressure; trouble urinating due to an enlarged prostate gland; cough that occurs with too much phlegm (mucus); persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema. Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin. When using this product do not use more than directed. Stop use and ask a doctor if: you get nervous, dizzy or sleepless; pain, nasal congestion or cough gets worse or lasts more than 5 days (children) or 7 days (adults); fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Cold
Directions
Dosage
Nighttime: Active Pharmaceutical Ingredient: Acetaminophen 650 mg Dextromethorphan HBr 20 mg Doxylamine succinate 12.5 mg Phenylephrine HCl 10 mg Daytime: Active Pharmaceutical Ingredient: Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg
Instructions
Nighttime Severe Cold & Flu: Directions: Take only as directed – see Overdose warning; only use the dose cup provided; do not exceed 4 doses per 24 hrs. Adults & children 12 yrs & over: 30 mL every 4 hours; children 4 to under 12 yrs: ask a doctor; children under 4 yrs: do not use. Daytime Severe Cold & Flu: Directions: Take only as directed – see Overdose warning; only use the dose cup provided; do not exceed 4 doses per 24 hrs. Adults & children 12 yrs & over: 30 mL every 4 hours; children 6 to under 12 yrs: 15 mL every 4 hrs; children 4 to under 6 yrs: ask a doctor; children under 4 yrs: do not use.
Ingredients
Inactive Ingredients
Daytime: butylated hydroxyanisole, edetate disodium, FD&C yellow #6, flavor, glycerin, menthol, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum Nighttime: butylated hydroxyanisole, edetate disodium, FD&C blue #1, FD&C red #40, flavor, glycerin, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum
Ingredients
Nighttime Severe Cold & Flu: Active ingredients (in each 30 mL): Acetaminophen 650 mg; Dextromethorphan HBr 20 mg; Doxylamine succinate 12.5 mg; Phenylephrine HCl 10 mg. Inactive ingredients: anhydrous citric acid, edetate disodium, FD&C blue #1, FD&C red #40, flavor, glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol solution, sucralose, xanthan gum. Daytime Severe Cold & Flu: Active ingredients (in each 15 mL): Acetaminophen 325 mg; Dextromethorphan HBr 10 mg; Guaifenesin 200 mg; Phenylephrine HCl 5 mg. Inactive ingredients: butylated hydroxyanisole, edetate disodium, FD&C yellow #6, flavor, glycerin, menthol, monobasic sodium phosphate, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sucrose, xanthan gum.
Active Ingredients
Phenylephrine HCl 5 mg Guaifenesin HBr 10 mg Dextromethorphan HBr 10 mg Acetaminophen 325 mg
Active Ingredient Name
Acetaminophen Dextromethorphan HBr Doxylamine succinate Phenylephrine HCl
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$897current price $8.9744.9 ¢/countEquate Maximum Strength Non Drowsy Daytime Severe Cold & Flu Softgels, 24 Count, Compare to Maximum Strength Mucinex® FAST-MAX® Daytime Cold & Flu & Night Time Cold & Flu Active Ingredients
774.6 out of 5 Stars. 77 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Maximum Strength Daytime & Nighttime Sinus Relief Softgels Combo Pack, 20 Count, Compare to Mucinex® Sinus-MAX® Day and Night Maximum Strength Active Ingredients $11.94 49.8 ¢/count
$1194current price $11.9449.8 ¢/countEquate Maximum Strength Daytime & Nighttime Sinus Relief Softgels Combo Pack, 20 Count, Compare to Mucinex® Sinus-MAX® Day and Night Maximum Strength Active Ingredients
1824.6 out of 5 Stars. 182 reviewsSave withShipping, arrives tomorrowTheraflu Max Strength Flu Symptom Relief - 20 Caplets Plus Theraflu Max Strength Nighttime Flu Medicine for Flu Symptom Relief- 20 Caplets Combo Pack $13.97 34.9 ¢/count
$1397current price $13.9734.9 ¢/countTheraflu Max Strength Flu Symptom Relief - 20 Caplets Plus Theraflu Max Strength Nighttime Flu Medicine for Flu Symptom Relief- 20 Caplets Combo Pack
9924.8 out of 5 Stars. 992 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Maximum Strength Mucus Relief DM Cough Suppressant and Expectorant Liquid, 6 fl oz $9.83 $1.64/fl oz
$983current price $9.83$1.64/fl ozEquate Maximum Strength Mucus Relief DM Cough Suppressant and Expectorant Liquid, 6 fl oz
5914.5 out of 5 Stars. 591 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Maximum Strength Day and Night Cold and Flu Relief Mini Softgels, 325mg, 16 Count $5.47 34.2 ¢/count
$547current price $5.4734.2 ¢/countEquate Maximum Strength Day and Night Cold and Flu Relief Mini Softgels, 325mg, 16 Count
1644.6 out of 5 Stars. 164 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Nighttime Max Strength Cold Flu Softgels, Compare to NyQuil Severe, 24 Count $7.98 33.3 ¢/count
$798current price $7.9833.3 ¢/countEquate Nighttime Max Strength Cold Flu Softgels, Compare to NyQuil Severe, 24 Count
4224.7 out of 5 Stars. 422 reviewsSave withShipping, arrives in 3+ daysRollback Equate Nighttime Severe Cold & Flu Relief, Sinus & Cough Relief, Honey, 12 fl oz $6.47 Was $8.98 53.9 ¢/fl oz
Rollback
Now$647current price Now $6.47, Was $8.98$8.9853.9 ¢/fl ozEquate Nighttime Severe Cold & Flu Relief, Sinus & Cough Relief, Honey, 12 fl oz
3374.5 out of 5 Stars. 337 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow500+ bought since yesterday Equate Daytime & Nighttime Multi-Symptom Cold Relief Caplets Combo Pack, 24 Count (2x12 Count) $4.98 20.8 ¢/count
500+ bought since yesterday
$498current price $4.9820.8 ¢/countEquate Daytime & Nighttime Multi-Symptom Cold Relief Caplets Combo Pack, 24 Count (2x12 Count)
25464.6 out of 5 Stars. 2546 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowEquate Maximum Strength Severe Congestion and Cough Liquid, 6 fl oz $8.62 $1.44/fl oz
$862current price $8.62$1.44/fl ozEquate Maximum Strength Severe Congestion and Cough Liquid, 6 fl oz
8704.6 out of 5 Stars. 870 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrowTheraflu Max Strength Cough Cold and Flu Day and Nighttime Relief Medicine Powder With Acetaminophen, 12 Count $13.97 $1.16/count
$1397current price $13.97$1.16/countTheraflu Max Strength Cough Cold and Flu Day and Nighttime Relief Medicine Powder With Acetaminophen, 12 Count
12304.8 out of 5 Stars. 1230 reviewsSave withPickup todayDelivery todayShipping, arrives tomorrow
Customer ratings & reviews
How item rating is calculated
Reviews summary
Pros
- : Offers great value for the product's functionality.
Neutral
- : Can be rich and smooth, but also bitter or unpleasant for some.
Generated by AI
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Showing 1-3 of 177 reviews
Oct 25, 2025
Alexis
5 out of 5 stars review
Verified Purchase
The relief was great.
I'm not a fan of most syrups of this type, but the cherry flavor was palatable for the time I used it. The soothing effect on my throat was immediate, and my coughing subsided in about 10 minutes. I would compare it well to its name brand counterpart. It helped me greatly through my serious fever.
Helpful?15QWD15FNR7639661521
Feb 3, 2026
Ruby
Top Reviewer
5 out of 5 stars review
Verified Purchase
Highly recommend
So my whole family and myself got sick, and I decided to buy this kind of medication, and I was very surprised of how fast the medication help us are get well fast. So if you or your family get sick of a cold flu or stuffy nose or a sore throat, this is going to help you get better very very fast so I highly recommend recommended to you and you to your family
Helpful?15QWD15FNR7639661521
Dec 20, 2025
Lisa
Top Reviewer
5 out of 5 stars review
Verified Purchase
Feel better fast for less
Works just as good as the absurdly priced name brands but can actually afford this one to start feeling better fast. Taste doesn't gag you like so many others do.
Helpful?15QWD15FNR7639661521
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