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Excedrin Extra Strength, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever Caplets for Headache Relief, 100 Count

4.8 stars out of 9412 reviews
(4.8)|
9,412 ratings

Key item features

  • One bottle of 100 Excedrin Extra Strength Caplets
  • Extra strength pain reliever that relieves pain associated with headache, colds, menstrual cramps, tooth pain, muscle pain and arthritis
  • Excedrin Extra Strength works in 3 ways: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance pain relief effect
  • Pain medicine that is a clinically proven headache pain reliever
  • Excedrin Extra Strength caplets contain two pain relievers and a booster for enhanced effect
  • Pain reliever available in convenient caplet form
  • For some, headache relief can start in 15 minutes
Current price is $12.7812.8 ¢/count
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Customer ratings & reviews

4.8 out of 5 stars
stars9,412 ratings6,446 reviews
How item rating is calculated

Reviews summary

Pros
  • : Offers excellent relief at a reasonable cost.
  • : Relieves pain quickly.
  • : Relieves various types of pain temporarily.
  • : Small enough to fit in a purse for on-the-go use.
  • : Made to withstand daily use.
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Showing 1-3 of 6,446 reviews

Oct 28, 2025
Mel
Item details
Count per pack: 24
5 out of 5 stars review

Verified Purchase

Wow! I rarely ever get headaches, but got a 2 day migraine out of nowhere. A friend suggested this and within the hour I could already feel relief. By my 2nd dose my severe migraine was completely gone. Great item at a reasonable price. Everyone is different; this was just my personal great experience.

Helpful?3RDVD0L61F4J10294261
Dec 9, 2025
Patricia
Item details
Count per pack: 200
5 out of 5 stars review

Verified Purchase

This combination of medications works better for my pain management than any other OTC or prescription medication I have ever used. Have had a lot of falls and injuries over the years (I am 77) and I have relied on it all of my adult life. It also works for headaches. I take it as prescribed and don't expect it to completely relieve pain…nothing does. But it enables me to do what I need to do and keep functioning better than without.

Helpful?3RDVD0L61F4J10294261
Sep 7, 2025
Kris
Item details
Count per pack: 100
5 out of 5 stars review

Verified Purchase

Excedrin doesn't disappoint

Nothing else on earth could come close to the power of excedrin. Knocked out headaches %26 body pains like no other. I've tried many different store brands to save a few dollars but ended up wasting money cuz they never work. The caffeine is also a pickup when I'm a bit sluggish.

Helpful?3RDVD0L61F4J10294261

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