Advantage II Vet-Recommended Flea Prevention for Large Cats 9 lbs+, 4-Monthly Treatments
Advantage II Vet-Recommended Flea Prevention for Large Cats 9 lbs+, 4-Monthly Treatments
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Advantage II Vet-Recommended Flea Prevention for Large Cats 9 lbs+, 4-Monthly Treatments

4.4 stars out of 4972 reviews
(4.4)|
4,972 ratings
Size:9 lbs+
Multipack Quantity:1
Count Per Pack:4

Key item features

  • Advantage II Large Cat is a leading brand in cat flea treatment and prevention for large cats over 9 lbs., at least 8 weeks of age
  • Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
  • Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
  • Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
  • Fragrance-free formula, waterproof after 24 hours of application
Current price is $51.9936.1 ¢/oz
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One-time purchase $51.99

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Customer ratings & reviews

4.4 out of 5 stars
stars4,972 ratings1,688 reviews
How item rating is calculated

Reviews summary

Pros
  • : Application process is straightforward.
  • : Provides quick relief from itching within hours or days.
  • : Reduces or stops scratching in cats.
  • : Pricing is comparable to or lower than others.
Neutral
  • : Can be odorless, but some users detect a strong or chemical smell.
  • : Effective against some pests, but struggles with others.
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Showing 1-3 of 1,688 reviews

Mar 8, 2025
Katheryn
Top Reviewer
Item details
Size: 9 lbs+
Multipack quantity: 1
Count per pack: 2
5 out of 5 stars review

Verified Purchase

The Best Flea Killer For A Big Kitty

I love the way this product takes care of my big boy! He knows when it is time for more, and he will stay in for a day because he cannot go out and get wet for 24 hrs after. He does it on his own. He is probably the smartest cat I have ever had, and I have had several for many years. I spent a lot of money on various flea remedies, and none worked on him. Advantage was great for some of my other animals, so I tried this one because my kitty is a big boy. It WORKS! No fleas, finally, after putting him through all those other sprays, pills, etc. So, I still need a tick killer cuz when I used this product, it was not enough! He is a 2 yr old that goes out and in every day. I got a tick collar, and he does well now without all the bugs. There is no smell either. The little vial that comes with the medication inside is REAL easy to apply. It is so easy to use; I love it. Just open the package, get the vial and put it on the cat's neck after pulling fur back. It may tickle the kitty for a minute or so. Also, it is normal that some liquid drains into the fur, but no worries.

Helpful?f2517840-427f-11ef-a3e2-e7329a6176f936650183
Oct 23, 2025
Maureen
Item details
Size: 5-9 lbs
Multipack quantity: 1
Count per pack: 2
5 out of 5 stars review

Verified Purchase

No more fleas. Happy cats.

I have used the other name brand for years. It is now starting to fail. It didn't even last for three weeks. So I decided to try Advantage II. I use this on all three of my cats as we recently somehow got a flea infestation. It worked wonderful. My cats have all stop scratching, and I can't find a single flea on them. I have found many dead fleas around their water dishes, but no life please. It works great and I definitely recommend this product.

Helpful?f2517840-427f-11ef-a3e2-e7329a6176f936650183
Nov 14, 2020
Sasha631
Item details
Size: 5-9 lbs
Multipack quantity: 1
Count per pack: 6
5 out of 5 stars review

Verified Purchase

Worked perfectly

I bought this when my 5 month old ragdoll cat wouldn’t stop scratching, and I found fleas on him. I put it on the back of his neck as directed and by the next day he had completely stopped scratching and he is very clearly much happier. I combed through his hair several times since putting it on (avoiding the area that was treated) and got out several fleas and flea dirt, and found flea eggs on my black desk (yuck)! But I’ll continue to use this once a month, it worked great and we had no side effects. We just make sure to vacuum several times a day, vacuum all sofas and surfaces, and spray with flea killer organic home spray. Very happy with the product.

Helpful?f2517840-427f-11ef-a3e2-e7329a6176f936650183