Chemical Biology Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering, Book 9, (Hardcover)

Disulphide bonds are important post-translational modifications of proteins that can covalently link cysteine residues far apart in the primary sequence of a protein. This can convey the needed stability to protein structures, but when incorrectly formed, these bonds interfere with folding or even cause aggregation, leading to disease. This book will begin with basic principles of disulphide bond formation. It then connects these to recent cell biological developments and ultimately the engineering of biomolecules and cells. This book will be an essential reference for advanced students and researchers in chemical biology and related fields who wish to gain the latest overview of this field.