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Equate Extra Strength Acetaminophen and Diphenhydramine HCl Nighttime Pain Relief Gelcaps, 20 Count

4.7 stars out of 4096 reviews
(4.7)|
4,096 ratings

Key item features

  • Equate Extra Strength Acetaminophen and Diphenhydramine HCI Pain Reliever PM Gelcaps, 20 Count
  • Extra strength pain reliever / nighttime sleep-aid
  • For the temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness
  • Active ingredients (in each gelcap): Acetaminophen 500 mg (pain reliever), Diphenhydramine HCl 25 mg (nighttime sleep-aid)
  • Suitable for adults and children 12 years and over
  • Compare to Extra Strength Tylenol PM active ingredients
  • Non-habit forming
Current price is $2.3811.9 ¢/count
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Customer ratings & reviews

4.7 out of 5 stars
stars4,096 ratings815 reviews
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Reviews summary

Pros

  • : Offers same quality at lower cost.
  • : Relieves various types of pain.
  • : Helps to calm the mind and body for sleep.
  • : Relieves headaches and promotes sleep.
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Showing 1-3 of 815 reviews

Apr 1, 2026
Mary
Top Reviewer
Item details
Count per pack: 80
5 out of 5 stars review

Verified Purchase

Great For Arthritis Pain

I have arthritis so bad, sleeping was almost impossible. Doctor prescribed a muscle relaxer that was only good for a few hours. My sister suggested I try these and so glad I did. Finally got a good night sleep. Even woke up with less pain for about an hour. Now using Equate version of arthritis strength Tylenol in daytime. No side effects thus far.

Helpful?5A23Q1D7LBVL730528912
Apr 10, 2026
Ashleigh
Top Reviewer
Item details
Count per pack: 80
5 out of 5 stars review

Verified Purchase

Equate Extra Strength PM Caplets

I usually only buy these when my regular brand isn't available, but they work the same. These caplets help take the edge off headaches and mild migraines, and the PM formula helps some people (not me) relax enough to actually get some rest instead of tossing and turning in pain. Getting good sleep when you're hurting makes a big difference, and these help with that. I'm not a huge fan of the pill size because they can be a little difficult to swallow sometimes, especially when you're already not feeling well. That said, the effectiveness makes up for it. They work very similar to the more expensive name brand versions, but at a much more affordable price. Overall, this is a solid budget-friendly option if you need nighttime pain relief. You don't always have to spend extra money just for the brand name when the Equate version provides the same relief and helps you get the rest you need.

Helpful?5A23Q1D7LBVL730528912
Jan 3, 2025
Karen
Top Reviewer
Item details
Count per pack: 80
5 out of 5 stars review

Verified Purchase

Easy prevention of pain waking you up

For a long time, if I woke up in the middle of the night because of pain. I thought I might try this instead of my prescription anti inflammatory. With my regular medicine I would have to get up and eat something so it wouldn't bother my stomach. Now, I know that acetaminophen isn't an anti inflammatory, but mix that with a sleep aid is a good idea for me.

Helpful?5A23Q1D7LBVL730528912