Instaflex Extra Strength Pain Relief Cream, with 2X The Pain-Fighting Ingredients, Rubs Out Your Toughest Muscle and Joint Pain (2 oz)
Instaflex Extra Strength Pain Relief Cream, with 2X The Pain-Fighting Ingredients, Rubs Out Your Toughest Muscle and Joint Pain (2 oz)
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Instaflex Extra Strength Pain Relief Cream, with 2X The Pain-Fighting Ingredients, Rubs Out Your Toughest Muscle and Joint Pain (2 oz)

About this item

  • INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM DELIVERS TWICE the menthol power of original Instaflex Pain Relief Cream, plus 2X the pain fighting ingredients. This formula also contains a proprietary blend of the same essential oxygenated oil included in original Instaflex, but with even more menthol and a new ingredient—methyl salicylate.
  • THE EXCLUSIVE OXYGENATED OIL IN INSTAFLEX, along with an ideal amount of soothing menthol, goes to work right at the source of your pain, working quickly to relieve pains, strains and joint and muscle pain. And it’s great for nighttime pain!
  • INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM HAS A PLEASANT SMELL AND NO GREASY FEEL. You will enjoy the pleasant, citrus scent, and non-greasy, easily absorbable formula with no burning, irritation, or harmful side effects.
  • DOCTOR DEVELOPED INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM was formulated by internationally recognized Dr. Joseph Pergolizzi, an actively practicing physician, and highly sought-after pain relief instructor, treating patients in his advanced Florida practice.

At a glance

Over-the-counter medicine type
Pain Relief
Product line
Instaflex
Age group
Adult
Form
Cream
Symptoms
Muscle & Joint Pain
Flavor
Citrus
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About this item

Product details

Doctor developed and formulated with an exclusive oxygenated oil to provide fast, extra strength relief from tough arthritis, back pain, strains, and joint/muscle pain that lasts for hours. Instaflex Extra Strength Pain Relief Cream delivers more menthol power than original Instaflex, plus 2X the pain-fighting ingredients.
  • INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM DELIVERS TWICE the menthol power of original Instaflex Pain Relief Cream, plus 2X the pain fighting ingredients. This formula also contains a proprietary blend of the same essential oxygenated oil included in original Instaflex, but with even more menthol and a new ingredient—methyl salicylate.
  • THE EXCLUSIVE OXYGENATED OIL IN INSTAFLEX, along with an ideal amount of soothing menthol, goes to work right at the source of your pain, working quickly to relieve pains, strains and joint and muscle pain. And it’s great for nighttime pain!
  • INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM HAS A PLEASANT SMELL AND NO GREASY FEEL. You will enjoy the pleasant, citrus scent, and non-greasy, easily absorbable formula with no burning, irritation, or harmful side effects.
  • DOCTOR DEVELOPED INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM was formulated by internationally recognized Dr. Joseph Pergolizzi, an actively practicing physician, and highly sought-after pain relief instructor, treating patients in his advanced Florida practice.
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Specifications

Over-the-counter medicine type

Pain Relief

Health concern

Arthritis, Bone & Joint Health

Active ingredients

Menthol (2.5%) Methyl Salicylate (10%)

Medicine strength

Menthol (2.5%) Methyl Salicylate (10%)

Indications

Stop Use Indications

If skin redness or excessive skin irritation develops Condition worsens or symptoms persist for more than 7 days Symptoms clear up and occur again in a few days

Health Concern

Arthritis Bone & Joint Health

Directions

Dosage

Directions Adults and children 12 years of age and older: Apply to affected area no more than 3-4 times daily. Children under 12 years of age: Consult a doctor.

Instructions

Apply to affected area no more than 3-4 times daily

Warranty

Warranty information

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Customer ratings & reviews

4.3 out of 5 stars
stars138 ratings45 reviews
How item rating is calculated

Reviews summary

Pros

  • : Relieves pain throughout the body.

Neutral

  • : Can be overpowering, but also subtle and pleasant.
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Showing 1-3 of 45 reviews

Nov 24, 2025
NS
5 out of 5 stars review

Seller Verified Purchase

It works

I purchased and within 7-10 days I felt a difference in the pain on my thigh/hip area. Recently, I took a fall causing a break of the hip. The pain lingered even after the wound healed, therefore I purchased Instaflex, so far it's working and has the pain at a minimum.

Review from Healthy Directions
Helpful?3B9FH107BBOK611746642
reply from Healthy Directions

Thank you for sharing your experience. We’re truly glad to hear that Instaflex Extra Strength Pain Relief Cream has been helping ease the lingering discomfort following your injury. Recovering from a fall and hip fracture can be a long journey, and it’s encouraging to know the product is bringing you some relief. If you ever have questions or need support with your order, we’re always here to help. Wishing you continued comfort and steady healing.

Feb 10, 2026
Walmart customer
5 out of 5 stars review

Seller Verified Purchase

The best cream.

I have used probably every pain relieving cream available and nothing has worked as well as Instaflex.

Review from Healthy Directions
Helpful?3B9FH107BBOK611746642
reply from Healthy Directions

Thank you for sharing that. Hearing that Instaflex Extra Strength Pain Relief Cream stands out compared to everything else you’ve tried really means a lot. We know how frustrating it can be to go through product after product without getting real relief, so it’s great to hear this one is making a noticeable difference for you. That’s exactly what it’s designed to do. We truly appreciate you taking the time to leave your feedback and are glad Instaflex is delivering the results you were looking for.

Nov 16, 2020
Thomas
5 out of 5 stars review

Seller Verified Purchase

Instaflex Cream

I have been using this daily for several months plus PT twice a week and am certain that the cream is an important factor in feeling more relief doubled with the PT,

Review from Healthy Directions
Helpful?3B9FH107BBOK611746642