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Nexium 24HR Acid Reducer Heartburn Relief Capsules for All-Day and All-Night Protection From Frequent Heartburn With Esomeprazole Magnesium, 42 Count

Key item features

  • Contents: One 42 day course of treatment: 42 Nexium 24HR Acid Reducer Heartburn Relief Capsules with Esomeprazole Magnesium
  • Blocks Acid at the Source for complete relief from frequent heartburn
  • Once Daily Heartburn Medicine: Just one Nexium 24HR a day gives you all day, all night relief from frequent heartburn
  • 20 mg NEXIUM 24HR delivers greater acid suppression for a longer period of time than omeprazole, the leading ingredient in other OTC PPI brands (3)
  • Blocks acid directly at the source to provide complete relief from frequent heartburn – no matter what triggers it
  • Join the millions who have chosen Nexium 24HR for their frequent heartburn.
  • Trusted Brand: From the makers of Advil, Centrum and Voltaren
  • HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
Current price is Now $25.00
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was $32.43
59.5 ¢/count
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4.405629139072848 stars out of 5, based on 608 seller reviews(4.4)
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Customer ratings & reviews

4.7 out of 5 stars
stars5,743 ratings1,791 reviews
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Reviews summary

Pros

  • : Relieves heartburn and acid reflux symptoms.
  • : Lasts throughout the day after morning intake.
  • : Simple to use and swallow without difficulty.
  • : Provides relief for a complete 24-hour period.
  • : Provides relief from heartburn with minimal side effects.

Neutral

  • : Offers competitive pricing, but can be pricey for some users.
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Showing 1-3 of 1,791 reviews

May 12, 2026
Bryan
Item details
Health concern: Acid Reflux
Multipack quantity: 3
5 out of 5 stars review

Verified Purchase

All day relief

Nexium is the solution for my acid reflux. I take one pill on an empty stomach at least an hour before I eat. Then, I have no symptoms for a whole day! It changed my life. I can eat and drink whatever and whenever I want without worrying about my acid reflux. It was prescribed by my doctor because I had developed Barrett's esophagus and was on the way to throat cancer. The Nexium hasn't given me any side effects whatsoever. I know studies have found some long-term side effects with proton pump inhibitors (of which Nexium is one). But, I've been taking it for 17 years without any problems.

Helpful?506L1H2XSTLH35284453
May 31, 2026
Benjamin
Item details
Health concern: Acid Reflux
Multipack quantity: 3
5 out of 5 stars review

Verified Purchase

Great Price and works well

I have acid reflux that inflamed my throat and made me cough constantly. My ENT recommended Nexium and it worked in just a few days along with a lower acid diet. I was on Famtodine but it wasn't working very well by itself. Walmart has a great price and value for the two bottle package.

Helpful?506L1H2XSTLH35284453
Feb 28, 2026
Mimi
Top Reviewer
Item details
Health concern: Acid Reflux
Multipack quantity: 3
5 out of 5 stars review

Verified Purchase

Dr recommended

When a surgical procedure done 25 years ago develops scars and medication causes discomfort when i swallow it after only 2-3 minutes that causes me to raise up to work through the pain, I need help. I was ordered an endoscopy colonoscopy and postoperatively prescribed Nexium minis. The gastroenterologist said he had no idea what they were?! Hmmmm

Helpful?506L1H2XSTLH35284453