Hero image 0 of Equate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients, 0 of 9
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Equate Nighttime Cold and Flu Relief Liquid, Original Flavor, 24 fl oz (2x12 fl oz), Compare to Vicks® Nyquil® Cold & Flu Active Ingredients
Key item features
- Active Ingredients: Compare to NyQuil Cold and Flu active ingredients: Acetaminophen (pain reliever and fever reducer), Dextromethorphan HBr (cough suppressant), and Doxylamine Succinate (antihistamine)
- Maximum Strength: Equate Nighttime Cold and Flu Relief provides maximum strength, multi-symptom relief to help you sleep
- Powerful Nighttime Relief: Each dose relieves minor aches and pains, fever, sore throat, sneezing, runny nose and cough for up to 6 hours so you can rest
- Liquid Medicine: Equate Nighttime Cold and Flu Relief is a liquid medicine in original flavor; get the relief you need in a liquid
- Ages 12 and Over: This cold and flu medicine is safe for adults and children ages 12 and over; gluten free
Specs
- Over-the-counter medicine typePain Relief, Fever Reducer, Cough & Cold, Flu Relief, Acetaminophen, Antihistamines
- Health concernCold, Flu, Body Aches & Pains
- BrandEquate
- Age groupAdult
- FormLiquid
- FlavorOriginal
Reviews summary
Pros
- : Helps promote restful night's sleep.
- : Costs less than similar products.
- : Relieves cold and flu symptoms quickly.
- : Works similarly to nyquil at a lower price point.
Cons
- : May be too intense for some users' preferences.
- : Lacks richness and density in its consistency.
Generated by AI
Current price is USDNow $9.97
You save $3.01
was $12.98$12.98
41.5 ¢/fl ozYou save$3.01
Price when purchased online
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About this item
Product details
Compare to NyQuil Cold and Flu active ingredients. Calm your cold and flu symptoms so you can get the rest you need. Equate Nighttime Cold and Flu provides powerful relief for your minor aches and pains, fever, sore throat, sneezing, runny nose and cough. Each dose combines Acetaminophen (pain reliever/fever reducer), Dextromethorphan HBr (cough suppressant) and Doxylamine Succinate (antihistamine) with ten percent alcohol to give you maximum strength, multi-symptom relief. This cold and flu liquid medicine in original flavor helps relieve major flu symptoms for up to 6 hours so you can rest. Dosage cup included. For ages 12 and over. This product does not contain gluten.
- Active Ingredients: Compare to NyQuil Cold and Flu active ingredients: Acetaminophen (pain reliever and fever reducer), Dextromethorphan HBr (cough suppressant), and Doxylamine Succinate (antihistamine)
- Maximum Strength: Equate Nighttime Cold and Flu Relief provides maximum strength, multi-symptom relief to help you sleep
- Powerful Nighttime Relief: Each dose relieves minor aches and pains, fever, sore throat, sneezing, runny nose and cough for up to 6 hours so you can rest
- Liquid Medicine: Equate Nighttime Cold and Flu Relief is a liquid medicine in original flavor; get the relief you need in a liquid
- Ages 12 and Over: This cold and flu medicine is safe for adults and children ages 12 and over; gluten free
info:
We aim to show you accurate product information. Manufacturers, suppliers and others provide what you see here, and we have not verified it.
Specifications
Over-the-counter medicine type
Pain Relief, Fever Reducer, Cough & Cold, Flu Relief, Acetaminophen, Antihistamines
Health concern
Cold, Flu, Body Aches & Pains
Active ingredients
Acetaminophen 650mg, Dextromethorphan HBr 30mg, Doxylamine succinate 12.5mg
Medicine strength
Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, Doxylamine succinate 12.5 mg
Indications
Stop Use Indications
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while using this product. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening; blisters; rash. If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist; if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product; if you have ever had an allergic reaction to this product or any of its ingredients. Ask a doctor before use if you have: liver disease; glaucoma; cough that occurs with too much phlegm (mucus); a breathing problem such as emphysema or chronic bronchitis; trouble urinating due to an enlarged prostate gland; persistent or chronic cough as occurs with smoking, asthma, or emphysema; a sodium-restricted diet. Ask a doctor or pharmacist before use if you are: taking sedatives or tranquilizers; taking the blood thinning drug warfarin. When using this product: excitability may occur, especially in children; marked drowsiness may occur; avoid alcoholic drinks; be careful when driving a motor vehicle or operating machinery; alcohol, sedatives, and tranquilizers may increase drowsiness. Stop use and ask a doctor if: pain or cough gets worse or lasts more than 7 days; fever gets worse or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Health Concern
Cold Flu Body Aches & Pains
Directions
Dosage
Do not take more than directed (see Overdose warning). Do not take more than 4 doses in any 24-hour period. Measure only with dosing cup provided. Do not use any other dosing device. mL = milliliter. Keep dosing cup with product. Adults and children 12 years and over: 30 mL every 6 hours. Children under 12 years of age: do not use. When using other Daytime or Nighttime products, carefully read each label to ensure correct dosing.
Instructions
Do not take more than directed (see Overdose warning). Do not take more than 4 doses in any 24-hour period. Measure only with dosing cup provided. Do not use any other dosing device. mL = milliliter. Keep dosing cup with product. Adults and children 12 years and over: 30 mL every 6 hours. Children under 12 years of age: do not use. When using other Daytime or Nighttime products, carefully read each label to ensure correct dosing.
Warranty
Warranty information
Ingredients
Inactive Ingredients
Inactive ingredients: acesulfame potassium, alcohol, citric acid, D&C yellow #10, FD&C green #3, FD&C yellow #6, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate. Each 30 mL contains: potassium 5 mg and sodium 19 mg.
Ingredients
Active Ingredients (in each 30 mL): Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, Doxylamine Succinate 12.5 mg. Inactive ingredients: acesulfame potassium, alcohol, citric acid, D&C yellow #10, FD&C green #3, FD&C yellow #6, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate. Each 30 mL contains: potassium 5 mg and sodium 19 mg.
Active Ingredients
Acetaminophen 650mg Dextromethorphan HBr 30mg Doxylamine succinate 12.5mg
Active Ingredient Name
Acetaminophen Dextromethorphan HBr Doxylamine succinate
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Customer ratings & reviews
How item rating is calculated
Reviews summary
Pros
- : Helps promote restful night's sleep.
- : Costs less than similar products.
- : Relieves cold and flu symptoms quickly.
- : Works similarly to nyquil at a lower price point.
Cons
- : May be too intense for some users' preferences.
- : Lacks richness and density in its consistency.
Generated by AI
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Showing 1-3 of 372 reviews
Jan 12, 2026
charles
Item details
Multipack quantity: 1
5 out of 5 stars review
Verified Purchase
Works
There is no reason that a signature should be required for delivery! I might could understand why if I ordered a pallet full, but just two bottles makes no sense what so ever!
Helpful?3Q8UFB5BQGEO21644823
Feb 4, 2026
Moirabeth
Item details
Multipack quantity: 1
5 out of 5 stars review
Verified Purchase
Great relief
Does not have a horrible taste like other. I mean, it's still medicine tasting. but doesn't turn my stomach. It works great! I could feel relief within 10-15 minutes.
Helpful?3Q8UFB5BQGEO21644823
May 24, 2025
MaryK
Item details
Multipack quantity: 1
5 out of 5 stars review
Verified Purchase
Relief-in-a-bottle!
When you feel awful-- especially with a cold-- Equate Nighttime Cold and Flu Liquid is no less than heaven-sent! Just like Nyquil, but it costs far less, this liquid relief-in-a-bottle covers all those awful symptoms that make you feel so terrible. This has been especially wonderful because my husband has been hit with spring allergies with a cold on top. He's finally gotten some relief and some sleep. (Yay!)
Helpful?3Q8UFB5BQGEO21644823
