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Equate Allergy Relief Diphenhydramine HCl 25 mg Antihistamine Tablets, 2x100 Count, Compare to Benadryl® Allergy Ultra tab® Active Ingredient

4.8 stars out of 5020 reviews
(4.8)|
5,020 ratings

Key item features

  • Equate antihistamine tablets are easy to swallow
  • Twin pack - two 100-count bottles inside
  • Diphenhydramine HCI, 25mg
  • Antihistamine
  • Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose, itchy watery eyes, sneezing, itching of the nose or throat
  • For adults and children 6 years of age and older
Current price is $7.443.7 ¢/count
Price when purchased online
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One-time purchase $7.44

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Customer ratings & reviews

4.8 out of 5 stars
stars5,020 ratings1,200 reviews
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Reviews summary

Pros
  • : Offers similar quality at a lower price point.
  • : Helps users fall asleep and stay asleep throughout the night.
  • : Helps alleviate seasonal and skin allergies in them.
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Showing 1-3 of 1,200 reviews

Jan 23, 2026
Dustin
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Works Great

This works just as good if not better then benadryl. I find that the price for the amount of pills you get is very good. Medicine is reliable, it helps decongest terrible allergies fast, clears out mucus and stops sneezing and allergy drawn headaches.

Helpful?4FAK0U0L0PK320629924
Oct 30, 2025
connie
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Good product for over the counter help

Still depend on Benadryl tablets. Not for sinus issues but for allergies with changing seasons. Never does it fail I itch in back of my knees or my nose itches. Sounds silly but it's true. Not to mention bug bites cause havoc with my skin and Benadryl only takes 15 minutes and I am good to go. Cant stop in my old years neither ! So Benadryl is the one !

Helpful?4FAK0U0L0PK320629924
Dec 28, 2025
Michael
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Good Anti-Histamine

As most people probably know this was originally a prescription only drug. That's why it is so effective. So to now have it over the counter and generic is a huge win for the consumer. Anti-histamines like all drugs are very effective for some but not so much for others. If you have allergies you know what a misery they can be. This works well for me with not too many side effects except it can cause a dry mouth and drowsiness pretty easily. So just be careful when you first start taking it. Heed the instructions and warnings on the box. Definitely worth a try!

Helpful?4FAK0U0L0PK320629924

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