Superstar genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in splicing DNA from different animals to create incredible new hybrids. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But when the pharmaceutical company that funds their research forbids it, they secretly take their experiment underground - risking their careers to push the boundaries of science and serve their own curiosity and ambition. The result is Dren, who exceeds their wildest dreams - and threatens to become their worst nightmare.
Featurette; "A Director's Playground: Vicenzo Natali on the Set of 'Splice'".
Language: English and Spanish; Subtitles: English and Spanish.