CETAPHIL Deep Hydration 48 Hour Activation Serum | 1 fl oz | 48 Hour Dry Skin Face Moisturizer for Sensitive Skin | With Hyaluronic Acid, Vitamin E & Vitamin B5 | Dermatologist Recommended
CETAPHIL Deep Hydration 48 Hour Activation Serum | 1 fl oz | 48 Hour Dry Skin Face Moisturizer for Sensitive Skin | With Hyaluronic Acid, Vitamin E & Vitamin B5 | Dermatologist Recommended
Hero image 0 of CETAPHIL Deep Hydration 48 Hour Activation Serum | 1 fl oz | 48 Hour Dry Skin Face Moisturizer for Sensitive Skin | With Hyaluronic Acid, Vitamin E & Vitamin B5 | Dermatologist Recommended, 0 of 8
Visit the Cetaphil Store

CETAPHIL Deep Hydration 48 Hour Activation Serum | 1 fl oz | 48 Hour Dry Skin Face Moisturizer for Sensitive Skin | With Hyaluronic Acid, Vitamin E & Vitamin B5 | Dermatologist Recommended

Key item features

  • Exclusive HydroSensitiv Complex deepens dynamic hydration and soothes skin sensitivity 
  • Deeply Replenishes Skin's Hydration for 48 Hours: To restore skin's appearance and improve the quality of sensitive skin over time
  • Instantly Absorbs & Layerable: Lightweight serum can be used alone or layered under face lotion or cream to provide a deep boost to skin's hydration
  • Ideal for Dry Skin and Dehydrated Skin: With Hyaluronic Acid, Vitamin B5 & Antioxidant Vitamin E to rehydrate and soothe
  • Designed for Sensitive Skin: Effective yet gentle skin care that won't clog pores or irritate skin; features a gentle scent & clinically tested on sensitive skin
  • From the #1 Doctor Recommended Sensitive Skincare Brand
Current price is $28.00$28.00/fl oz
Price when purchased online
Out of stock

How do you want your item?

How do you want your item?
Out of stock

About this item

Product details

Specifications

Indications

Directions

Ingredients

Refine your search

Customer ratings & reviews

4.4 out of 5 stars
stars280 ratings255 reviews
How item rating is calculated
  1. 5 stars67% (187)
  2. 4 stars20% (57)
  3. 3 stars5% (13)
  4. 2 stars4% (10)
  5. 1 star5% (13)

Reviews summary

Pros

  • : Leaves skin hydrated without greasiness.
  • : Provides long-lasting moisture without residue.
  • : Absorbs rapidly into skin without residue.
  • : Absorbs into skin quickly without leaving residue.
  • : Has a subtle fragrance.
Generated by AI

Customer photos

  • +129 images
Filtered and sorted results would be available on the new 'Customer ratings & reviews' page.
Sort by |

Showing 1-3 of 255 reviews

Jan 29, 2026
nahomism_4605
5 out of 5 stars review

Lightweight serum that absorbs fast and delivers l

I've been using the Cetaphil Deep Hydration 48 Hour Activation Serum and it has been amazing for my skin. It absorbs quickly, feels lightweight, and provides long-lasting hydration without feeling greasy. My skin feels softer, smoother, and more comfortable all day. It works great for sensitive skin and layers well under moisturizer or makeup.

Review from influenster.com
Helpful?7HQ8GEJRMLAB147005277
Jan 27, 2026
leahp295_2736
5 out of 5 stars review

Must have

This is a great product! I truly enjoy the feel of the serum on my skin it's extremely hydrating!!I love this company I have t tried anything I haven't loved. Get this!

Review from influenster.com
Helpful?7HQ8GEJRMLAB147005277
Sep 23, 2025
mennadelvey_2715
5 out of 5 stars review

Long-Lasting Hydration Boost

Cetaphil Deep Hydration 48 Hour Activation Serum provides intense, lasting hydration with hyaluronic acid and HydroSensitiv Complex. It strengthens the skin barrier, leaving skin soft, plump, and refreshed for up to 48 hours. Lightweight, fast-absorbing, and perfect for daily use.

Review from influenster.com
Helpful?7HQ8GEJRMLAB147005277