When using this product mild increase in vaginal burning, itching or irritation may occur. All Perrigo products must meet approved specifications for identity and strength prior to release for public use. Individual will vary in the way they respond to the same dose of a single drug. The difference in response can result from a number of factors responsible for altering the drug effect that include genetics, disease, age and use of other drugs at the same time. We would like to thank you for the opportunity to address your concern. As you may already know, we are required by the Food and Drug Administration (FDA) to obtain as much information as possible on adverse events associated with the use of our products. In order for us to better understand the events that occurred and file a complete report, we are asking for you to contact us. Please contact us and use the case number 653392 as a reference for this issue. We can be reached by phone at 866-634-9120, Monday through Friday 7:30am - 5pm ET. If we do not hear from you within two weeks, we will consider this matter closed.