I've been using Azo Yeast for years, taking one pill daily to prevent yeast infections & it has worked like a charm. However, upon trying the new Azo Yeast Plus, I soon developed a yeast infection. There have been no other changes since switching to the Plus formula (same diet, hygiene, exersize & cotton clothing, etc.) However, now that I've compared the two boxes, the ingredients are different! I've gone to area stores & stocked up on the old version before it is completely replaced. I am sad to see this change & will sorely miss the regular Azo Yeast formula (no pun intended).