Pharmacology and Therapeutics of Cough

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Pharmacology and Therapeutics of Cough

Format:  Hardcover,

375 pages

Publisher: Springer Verlag

Publish Date: Oct 2008

ISBN-13: 9783540798415

ISBN-10: 3540798412

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The last decade has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the pharmacological receptors on their membranes, the brainstem organization of the cough centre, and the involvement of the cerebral cortex in the sensations and the voluntary control of cough. This book shows that basic studies are pointing to many potentially valuable approaches to the treatment of cough, based on understanding the basic peripheral receptor mechanisms, the brainstem pathways in the control of cough, and the sensitization processes that may apply in disease.

Specifications

Editor:
Contribution by:
Publisher: Springer Verlag
Publish Date: Oct 2008
ISBN-13: 9783540798415
ISBN-10: 3540798412
Format: Hardcover
Number of Pages: 375
Shipping Weight (in pounds): 1.4
Product in Inches (L x W x H): 6.2 x 0.7 x 9.3
Walmart No.: 9783540798415

Chapter outline

Cough: Setting the Scenep. 1
Cough Sensors. I. Physiological and Pharmacological Properties of the Afferent Nerves Regulating Coughp. 23
Cough Sensors. II. Transient Receptor Potential Membrane Receptors on Cough Sensorsp. 49
Cough Sensors. III. Opioid and Cannabinoid Receptors on Vagal Sensory Nervesp. 63
Cough Sensors. IV. Nicotinic Membrane Receptors on Cough Sensorsp. 77
Cough Sensors. V. Pharmacological Modulation of Cough Sensorsp. 99
Peripheral Mechanisms I: Plasticity of Peripheral Pathwaysp. 129
Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugsp. 155
Central Mechanisms I: Plasticity of Central Pathwaysp. 187
Central Mechanisms II: Pharmacology of Brainstem Pathwaysp. 203
Central Mechanisms III: Neuronal Mechanisms of Action of Centrally Acting Antitussives Using Electrophysiological and Neurochemical Study Approachesp. 219
Central Mechanisms IV: Conscious Control of Cough and the Placebo Effectp. 241
Clinical Cough I: The Urge-To-Cough: A Respiratory Sensationp. 263
Clinical Cough II: Therapeutic Treatments and Management of Chronic Coughp. 277
Clinical Cough III: Measuring the Cough Response in the Laboratoryp. 297
Clinical Cough IV: What is the Minimal Important Difference for the Leicester Cough Questionnaire?p. 311
Clinical Cough V: Complementary and Alternative Medicine: Therapy of Coughp. 321
Clinical Cough VI: The Need for New Therapies for Cough: Disease-Specific and Symptom-Related Antitussivesp. 343
Indexp. 369

Book description

The last decade has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the pharmacological receptors on their membranes, the brain stem organization of the 'cough centre', and the involvement of the cerebral cortex in the sensations and the voluntary control of cough. This book shows that basic studies are pointing to many potentially valuable approaches to the treatment of cough, based on understanding the basic peripheral receptor mechanisms, the brain stem pathways in the control of cough, and the sensitization processes that may apply in disease.

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